Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Nikolai, Fattakhov"'
Autor:
Silvia Torices, Leah Daire, Sierra Simon, Oandy Naranjo, Luisa Mendoza, Timea Teglas, Nikolai Fattakhov, Daniel Adesse, Michal Toborek
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Compromised structure and function of the blood-brain barrier (BBB) is one of the pathological hallmarks of brain infection by HIV-1. BBB damage during HIV-1 infection has been associated with modified expression of tight junction (TJ) prote
Externí odkaz:
https://doaj.org/article/be2bb48628934c6abf7b98937d2365e4
Autor:
Igor Y Iskusnykh, Nikolai Fattakhov, Yiran Li, Laure Bihannic, Matthew K Kirchner, Ekaterina Y Steshina, Paul A Northcott, Victor V Chizhikov
Publikováno v:
eLife, Vol 12 (2023)
Development of the nervous system depends on signaling centers – specialized cellular populations that produce secreted molecules to regulate neurogenesis in the neighboring neuroepithelium. In some cases, signaling center cells also differentiate
Externí odkaz:
https://doaj.org/article/a7a09d4cbfff4e7e96e2c9452b75695c
Autor:
Oandy Naranjo, Silvia Torices, Paul R. Clifford, Manav T. Daftari, Olivia M. Osborne, Nikolai Fattakhov, Michal Toborek
Publikováno v:
Retrovirology, Vol 19, Iss 1, Pp 1-9 (2022)
Abstract While HIV-1 is primarily an infection of CD4 + T cells, there is an emerging interest towards understanding how infection of other cell types can contribute to HIV-associated comorbidities. For HIV-1 to cross from the blood stream into tissu
Externí odkaz:
https://doaj.org/article/fe1d23929df24ad495c3baaceb18c726
Autor:
Silvia Torices, Rosalba Cabrera, Michael Stangis, Oandy Naranjo, Nikolai Fattakhov, Timea Teglas, Daniel Adesse, Michal Toborek
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background Neurological complications are common in patients affected by COVID-19 due to the ability of SARS-CoV-2 to infect brains. While the mechanisms of this process are not fully understood, it has been proposed that SARS-CoV-2 can infe
Externí odkaz:
https://doaj.org/article/03e20f5f5bf546eb8ba5d8aac9a127d7
Autor:
Victor V. Chizhikov, Igor Y. Iskusnykh, Ekaterina Y. Steshina, Nikolai Fattakhov, Anne G. Lindgren, Ashwin S. Shetty, Achira Roy, Shubha Tole, Kathleen J. Millen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The contribution of long-range signaling to cortical gyrification remains poorly understood. In this study, authors demonstrate that the combined genetic loss of transcription factors Lmx1a and Lmx1b, expressed in the telencephalic dorsal midline neu
Externí odkaz:
https://doaj.org/article/5e9a3cae7cdf4bcbae7688176c6be113
Autor:
Florian Freudenberg, Esin Candemir, Xufeng Chen, Li-Li Li, Dilhan Esen-Sehir, Nicole Schenk, Makoto Kinoshita, Lena Grünewald, Veronika Frerichs, Nikolai Fattakhov, Jessica Manchen, Solmaz Bikas, Anita Kumar, Aet OLeary, David A. Slattery, Jakob von Engelhardt, Michael J. Courtney, Andreas Reif
Publikováno v:
EBioMedicine, Vol 71, Iss , Pp 103565- (2021)
Background: Nitric oxide synthase 1 adaptor protein (NOS1AP; previously named CAPON) is linked to the glutamatergic postsynaptic density through interaction with neuronal nitric oxide synthase (nNOS). NOS1AP and its interaction with nNOS have been as
Externí odkaz:
https://doaj.org/article/38cf142210fc4beeb6a89b3aa32c23c7
Publikováno v:
Viruses, Vol 13, Iss 9, p 1883 (2021)
The neurovascular units (NVU) are the minimal functional units of the blood–brain barrier (BBB), composed of endothelial cells, pericytes, astrocytes, microglia, neurons, and the basement membrane. The BBB serves as an important interface for immun
Externí odkaz:
https://doaj.org/article/b126a91f02a94d23ac75f575b17a134b
Autor:
Ibolya E. András, Nelson Serrano, Irina Djuraskovic, Nikolai Fattakhov, Enze Sun, Michal Toborek
Brain endothelial extracellular vesicles carrying amyloid beta (EV-Aβ) can be transferred to neural progenitor cells (NPCs) leading to NPC dysfunction. However, the events involved in this EV-mediated Aβ pathology are unclear. EV-proteomics studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23edf4e739439b888d4b648062970aaf
https://doi.org/10.21203/rs.3.rs-2551245/v1
https://doi.org/10.21203/rs.3.rs-2551245/v1
Autor:
Igor Y. Iskusnykh, Evgenii D. Kryl’skii, Darya A. Brazhnikova, Tatyana N. Popova, Khidmet S. Shikhaliev, Konstantin K. Shulgin, Larisa V. Matasova, Sergey S. Popov, Dmitry A. Zhaglin, Anastasia A. Zakharova, Nelli R. Popova, Nikolai Fattakhov
Publikováno v:
Antioxidants, Vol 10, Iss 1, p 122 (2021)
Inflammation and an increase in antioxidant responses mediated by oxidative stress play an important role in the pathogenesis of acute liver injury (ALI). We utilized in silico prediction of biological activity spectra for substances (PASS) analysis
Externí odkaz:
https://doaj.org/article/89915621c26b47208c6a70c535c9e9b8
Autor:
Silvia Torices, Timea Teglas, Oandy Naranjo, Nikolai Fattakhov, Kristyna Frydlova, Rosalba Cabrera, Olivia M. Osborne, Enze Sun, Allan Kluttz, Michal Toborek
HIV-1-associated blood brain barrier (BBB) alterations and neurocognitive disorders are frequent clinical manifestations in HIV-1 infected patients. The BBB is formed by cells of the neurovascular unit (NVU) and sealed together by tight junction (TJ)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::651c5ff7dc058fbabcf09b25c708b72c
https://doi.org/10.21203/rs.3.rs-2501091/v1
https://doi.org/10.21203/rs.3.rs-2501091/v1