Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nikola Skoupa"'
Publikováno v:
Biomolecules, Vol 10, Iss 1, p 77 (2020)
Lysosomal sequestration of anticancer therapeutics lowers their cytotoxic potential, reduces drug availability at target sites, and contributes to cancer resistance. Only recently has it been shown that lysosomal sequestration of weak base drugs indu
Externí odkaz:
https://doaj.org/article/bb1e6bafa63b4d62a61680ccf17db1ad
Publikováno v:
Biomolecules, Vol 9, Iss 11, p 675 (2019)
The Lysosomal sequestration of weak-base anticancer drugs is one putative mechanism for resistance to chemotherapy but it has never been directly proven. We addressed the question of whether the lysosomal sequestration of tyrosine kinase inhibitors (
Externí odkaz:
https://doaj.org/article/f5f6c1ee80514fdcb14acd203105c0f0
Publikováno v:
Biomolecules
Volume 10
Issue 1
Biomolecules, Vol 10, Iss 1, p 77 (2020)
Volume 10
Issue 1
Biomolecules, Vol 10, Iss 1, p 77 (2020)
Lysosomal sequestration of anticancer therapeutics lowers their cytotoxic potential, reduces drug availability at target sites, and contributes to cancer resistance. Only recently has it been shown that lysosomal sequestration of weak base drugs indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3fd2bb8eb28893f7c377378d4a3b75d
http://europepmc.org/articles/PMC7022710
http://europepmc.org/articles/PMC7022710
Publikováno v:
Environmental toxicology and pharmacology. 71
Although cadmium (Cd2+) is unable to form reactive oxygen species (ROS) directly, many of its adverse effects are connected to increased ROS generation resulting in cell death. In support of this supposition, a large number of studies have shown prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf16a8207a7f8d939647437938ba7fc
https://pubmed.ncbi.nlm.nih.gov/31288199
https://pubmed.ncbi.nlm.nih.gov/31288199
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2289 (2017)
International Journal of Molecular Sciences; Volume 18; Issue 11; Pages: 2289
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2289 (2017)
International Journal of Molecular Sciences; Volume 18; Issue 11; Pages: 2289
The synthetic curcumin analogue, 3,5-bis[(2-fluorophenyl)methylene]-4-piperidinone (EF-24), suppresses NF-κB activity and exhibits antiproliferative effects against a variety of cancer cells in vitro. Recently, it was reported that EF-24-induced apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925742af84ff446eb727e53593f03277
http://europepmc.org/articles/PMC5713259
http://europepmc.org/articles/PMC5713259
Publikováno v:
Drug Metabolism and Pharmacokinetics. 34:S21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff4d21c6102a1dd0620137377bb0c1cb
https://doi.org/10.1016/j.dmpk.2018.09.090
https://doi.org/10.1016/j.dmpk.2018.09.090
Publikováno v:
Drug Metabolism and Pharmacokinetics. 32:S69-S70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::730f9c0879b3c39c45e779d9ed8f6677
https://doi.org/10.1016/j.dmpk.2016.10.279
https://doi.org/10.1016/j.dmpk.2016.10.279