Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Nikola Ojkic"'
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Bacteria have evolved to develop multiple strategies for antibiotic resistance by effectively reducing intracellular antibiotic concentrations or antibiotic binding affinities, but the role of cell morphology in antibiotic resistance remains
Externí odkaz:
https://doaj.org/article/a308c4d3314340db866268dd2eb3812c
Publikováno v:
Cell Reports, Vol 32, Iss 12, Pp 108183- (2020)
Summary: Cell size control emerges from a regulated balance between the rates of cell growth and division. In bacteria, simple quantitative laws connect cellular growth rate to ribosome abundance. However, it remains poorly understood how translation
Externí odkaz:
https://doaj.org/article/344c6ea999c14da9bb4dd3f8a6e3d618
Publikováno v:
eLife, Vol 8 (2019)
Rod-shaped bacterial cells can readily adapt their lengths and widths in response to environmental changes. While many recent studies have focused on the mechanisms underlying bacterial cell size control, it remains largely unknown how the coupling b
Externí odkaz:
https://doaj.org/article/8848dc2d0f454fecbd6d9e8f2aaf2851
Publikováno v:
eLife, Vol 5 (2016)
When starved, the Gram-positive bacterium Bacillus subtilis forms durable spores for survival. Sporulation initiates with an asymmetric cell division, creating a large mother cell and a small forespore. Subsequently, the mother cell membrane engulfs
Externí odkaz:
https://doaj.org/article/02f04063b2e04f23ad2182670e3c4dc6
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 10, p e1003912 (2014)
To survive starvation, the bacterium Bacillus subtilis forms durable spores. The initial step of sporulation is asymmetric cell division, leading to a large mother-cell and a small forespore compartment. After division is completed and the dividing s
Externí odkaz:
https://doaj.org/article/2e96d4cfac7c4f4a8314771b6bc1ae27
Autor:
Shiladitya Banerjee, Nikola Ojkic, Norbert F. Scherer, Roisin Stephens, Klevin Lo, Aaron R. Dinner
Publikováno v:
Nature Physics. 17:403-409
To maximize their fitness, cells must be able to respond effectively to stresses. This demands making trade-offs between processes that conserve resources to promote survival, and processes that use resources to promote growth and division. Understan
Autor:
Georgina Benn, Maxim G. Ryadnov, Irina V. Mikheyeva, Bart W. Hoogenboom, Joel C. Forster, Thomas J. Silhavy, Nikola Ojkic, Patrick George Inns, Colin Kleanthous, Christian Bortolini
Publikováno v:
Proceedings of the National Academy of Sciences. 118
Gram-negative bacteria are surrounded by a protective outer membrane (OM) with phospholipids in its inner leaflet and lipopolysaccharides (LPS) in its outer leaflet. The OM is also populated with many β-barrel outer-membrane proteins (OMPs), some of
Publikováno v:
Antimicrob Agents Chemother
Ojkic, N, Lilja, E, Oliveira Lebre Direito, S, Dawson, A, Allen, R J & Waclaw, B 2020, ' A roadblock-and-kill mechanism of action model for the DNA-targeting antibiotic ciprofloxacin ', Antimicrobial Agents and Chemotherapy, vol. 64, no. 9, e02487-19, pp. 1-17 . https://doi.org/10.1128/AAC.02487-19
Ojkic, N, Lilja, E, Oliveira Lebre Direito, S, Dawson, A, Allen, R J & Waclaw, B 2020, ' A roadblock-and-kill mechanism of action model for the DNA-targeting antibiotic ciprofloxacin ', Antimicrobial Agents and Chemotherapy, vol. 64, no. 9, e02487-19, pp. 1-17 . https://doi.org/10.1128/AAC.02487-19
Fluoroquinolones, antibiotics that cause DNA damage by inhibiting DNA topoisomerases, are clinically important, but their mechanism of action is not yet fully understood. In particular, the dynamical response of bacterial cells to fluoroquinolone exp
SUMMARY Cell size control emerges from a regulated balance between the rates of cell growth and division. In bacteria, simple quantitative laws connect cellular growth rate to ribosome abundance. However, it remains poorly understood how translation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84b34219190abd0dc9476c988e03aa8
Publikováno v:
bioRxiv
Fluoroquinolones - antibiotics that cause DNA damage by inhibiting DNA topoisomerases - are clinically important, but their mechanism of action is not yet fully understood. In particular, the dynamical response of bacterial cells to fluoroquinolone e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a8bfb6158b1d72ccebcac060ad162c
https://doi.org/10.1101/791145
https://doi.org/10.1101/791145