Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nikola Kaludov"'
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125593 (2015)
Without quantum theory any understanding of molecular interactions is incomplete. In principal, chemistry, and even biology, can be fully derived from non-relativistic quantum mechanics. In practice, conventional quantum chemical calculations are com
Externí odkaz:
https://doaj.org/article/a4052666f84d40aab8f17892c4d30b4e
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9336 (2010)
Cell surface carbohydrates play an important role in virus entry and intracellular trafficking. Bovine Adeno-Associated Virus (BAAV) uses plasma membrane gangliosides for transduction and infection. In addition, independent of the infectious pathway,
Externí odkaz:
https://doaj.org/article/88ff38271da2466cbae6d5afce26a383
Autor:
Amatul Nasir Salma, Hemantkumar Tripathi, Yair Lotan, Gary D. Steinberg, Max Kates, Nikola Kaludov, M. Minhaj Siddiqui
Publikováno v:
Journal of Clinical Oncology. 37:e16008-e16008
e16008 Background: Urine tests such as urine cytology are commonly used for the diagnosis and monitoring of urothelial cancer. These tests are often limited by issues related to sensitivity or specificity. It is well known that derangement of cellula
Autor:
Jeffrey A. Johnson, Sara Amirahmadi, Delinda A. Johnson, Gururaj Joshi, Nikola Kaludov, Martin N. Martinov, Tracy P. Williamson
Publikováno v:
Chemical Biology & Drug Design. 80:810-820
Nuclear factor erythroid 2-related factor 2 (Nrf2) is the master transcription factor of the antioxidant response element pathway, coordinating the induction of detoxifying and antioxidant enzymes. Nrf2 is normally sequestered in the cytoplasm by Kel
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125593 (2015)
PLoS ONE
PLoS ONE
Without quantum theory any understanding of molecular interactions is incomplete. In principal, chemistry, and even biology, can be fully derived from non-relativistic quantum mechanics. In practice, conventional quantum chemical calculations are com
Autor:
Valorie D. Bowman, Eric Padron, Lakshmanan Govindasamy, Nikola Kaludov, Mavis Agbandje-McKenna, Hazel C. Levy, John A. Chiorini, Phillip Nick, Timothy S. Baker, Robert McKenna, Nicholas Muzyczka
Publikováno v:
Journal of Virology. 79:5047-5058
Adeno-associated virus (AAV) is a member of the Parvoviridae , belonging to the Dependovirus genus. Currently, several distinct isolates of AAV are in development for use in human gene therapy applications due to their ability to transduce different
Publikováno v:
Human Gene Therapy. 13:1235-1243
The availability of high-titer, high-purity, adeno-associated virus type 2 (AAV2) stocks has dramatically increased our understanding of this virus and its utility as a gene transfer vector. Current methods of purification take advantage of the stabl
Publikováno v:
Journal of Biological Chemistry. 272:15120-15127
H1 histones, found in all multicellular eukaryotes, associate with linker DNA between adjacent nucleosomes, presumably to keep the chromatin in a compact, helical state. The identification of multiple histone H1 subtypes in vertebrates suggests these
Publikováno v:
Nucleic Acids Research. 24:523-531
Replication-dependent histone genes of all four nucleosomal classes are coordinately up-regulated at the beginning of S phase of the eukaryotic cell cycle. The universality and importance of this process in eukaryotic cells suggest that common regula
Publikováno v:
Malaria Journal, Vol 10, Iss 1, p 274 (2011)
Malaria Journal
Malaria Journal
Background Developing resistance towards existing anti-malarial therapies emphasize the urgent need for new therapeutic options. Additionally, many malaria drugs in use today have high toxicity and low therapeutic indices. Gradient Biomodeling, LLC h