Zobrazeno 1 - 10
of 257
pro vyhledávání: '"Nikola, Sprigg"'
Autor:
Chen Chen, Yapeng Lin, Feifeng Liu, Xiaoying Chen, Laurent Billot, Qiang Li, Yiija Guo, Hueiming Liu, Lei Si, Menglu Ouyang, Chunfang Zhang, Hisatomi Arima, Philip M. Bath, Gary A. Ford, Thompson Robinson, Else Charlotte Sandset, Jeffrey L. Saver, Nikola Sprigg, H. Bart van der Worp, Gang Liu, Lili Song, Jie Yang, Gang Li, Craig S. Anderson, for the INTERACT4 Investigators
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background and aims Uncertainty persists over the effects of blood pressure (BP) lowering in acute stroke. The INTEnsive ambulance-delivered blood pressure Reduction in hyper-Acute stroke Trial (INTERACT4) aims to determine efficacy and safe
Externí odkaz:
https://doaj.org/article/db70d4115dfe401397d3fbea50c3640b
Autor:
Rais Reskiawan A. Kadir, Kamini Rakkar, Othman A. Othman, Nikola Sprigg, Philip M. Bath, Ulvi Bayraktutan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Endothelial progenitor cells (EPCs), expressing markers for stemness (CD34), immaturity (CD133) and endothelial maturity (KDR), may determine the extent of post-stroke vascular repair. Given the prevalence of stroke in elderly, this study ex
Externí odkaz:
https://doaj.org/article/845536bb1a8c454b9ac61ee52e634038
Autor:
Lisa J. Woodhouse, Jason P. Appleton, Hanne Christensen, Rob A. Dineen, Timothy J. England, Marilyn James, Kailash Krishnan, Alan A. Montgomery, Anna Ranta, Thompson G. Robinson, Nikola Sprigg, Philip M. Bath
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Intensive antiplatelet therapy did not reduce recurrent stroke/transient ischaemic attack (TIA) events as compared with guideline treatment in the Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke (TARDIS) trial, but did in
Externí odkaz:
https://doaj.org/article/9c7b9b2006c74f83a10cb29284475d26
Autor:
Grant Mair, Philip White, Philip M. Bath, Keith Muir, Chloe Martin, David Dye, Francesca Chappell, Rüdiger vonKummer, Malcolm Macleod, Nikola Sprigg, Joanna M. Wardlaw, for the RITeS Collaboration
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 7, Pp 1072-1082 (2023)
Abstract Objective Software developed using artificial intelligence may automatically identify arterial occlusion and provide collateral vessel scoring on CT angiography (CTA) performed acutely for ischemic stroke. We aimed to assess the diagnostic a
Externí odkaz:
https://doaj.org/article/0ef113e3813d4edba87369cbfe618482
Autor:
Ellen V Backhouse, Lisa J Woodhouse, Fergus Doubal, Rosalind Brown, Philip M Bath, Terence J Quinn, Thompson Robinson, Hugh S Markus, Richard J McManus, John T O'Brien, David J Werring, Nikola Sprigg, Adrian Parry-Jones, Rhian M Touyz, Steven Williams, Yee-Haur Mah, Hedley Emsley, Joanna M Wardlaw
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100255- (2024)
Introduction: Cognitive decline and mood disorders are two major concerns of people affected by stroke. The extent to which cognition and mood relate to or are independent of stroke severity and post-stroke dependency are unclear. We examined the ass
Externí odkaz:
https://doaj.org/article/269e2a22e8064bf1905bce2fc9fc505b
Autor:
Kailash Krishnan, Paula Bermell Campos, Thanh N. Nguyen, Chia Wei Tan, Siang Liang Chan, Jason P. Appleton, ZheKang Law, Milo Hollingworth, Matthew A. Kirkman, Timothy J. England, Christine Roffe, Mary Joan Macleod, Jesse Dawson, Ulvi Bayraktutan, David J. Werring, Nikola Sprigg, Philip M. Bath
Publikováno v:
Frontiers in Stroke, Vol 2 (2023)
Acute intracerebral hemorrhage is the most devastating stroke subtype and is associated with significant morbidity and mortality. Poor prognosis is associated with primary brain injury from the presenting hematoma, and despite advances in clinical tr
Externí odkaz:
https://doaj.org/article/e796333981e4465c83dd7bdacb844ddb
Autor:
Vaanathi Sundaresan, Christoph Arthofer, Giovanna Zamboni, Andrew G. Murchison, Robert A. Dineen, Peter M. Rothwell, Dorothee P. Auer, Chaoyue Wang, Karla L. Miller, Benjamin C. Tendler, Fidel Alfaro-Almagro, Stamatios N. Sotiropoulos, Nikola Sprigg, Ludovica Griffanti, Mark Jenkinson
Publikováno v:
Frontiers in Neuroinformatics, Vol 17 (2023)
IntroductionCerebral microbleeds (CMBs) are associated with white matter damage, and various neurodegenerative and cerebrovascular diseases. CMBs occur as small, circular hypointense lesions on T2*-weighted gradient recalled echo (GRE) and susceptibi
Externí odkaz:
https://doaj.org/article/ee9b9d7ea4384217946165ef86d8997d
Autor:
Joanna M Wardlaw, Jeffrey L Saver, Philip M Bath, Thompson G Robinson, Keith Muir, Jason P Appleton, Lisa J Woodhouse, Nikola Sprigg, Marc Randall, Christine Roffe, Else C Sandset, Christopher I Price, Grant Mair, Stuart Pocock, Timothy J England, Aloysius Niroshan Siriwardena, Sandeep Ankolekar
Publikováno v:
BMJ Neurology Open, Vol 5, Iss 1 (2023)
Background The Rapid Intervention with Glyceryl Trinitrate in Hypertensive Stroke Trial-2 (RIGHT-2) reported no overall treatment difference between glyceryl trinitrate (GTN) and sham at day 90. Here we assess participants’ outcomes 1 year after ra
Externí odkaz:
https://doaj.org/article/ce3eabd18ce34e35918de9d48eace3e2
Autor:
Kailash Krishnan, Thanh N. Nguyen, Jason P. Appleton, Zhe Kang Law, Mark Caulfied, Claudia P. Cabrera, Rob Lenthall, David Hewson, Timothy England, Norman McConachie, Permesh Dhillon, Luqman Malik, Anna Podlasek, Craig J. Smith, Jesse Dawson, Thompson G. Robinson, Nikola Sprigg, Martin A. James, Phil White, Michael J.R. Desborough, Joannes Hermans, Philip M. Bath
Publikováno v:
Stroke: Vascular and Interventional Neurology, Vol 3, Iss 3 (2023)
Acute ischemic stroke is a leading cause of death and major disability worldwide. Approximately 50% of ischemic strokes are caused by atherothrombotic occlusion of the cerebral arteries, and antiplatelets are the mainstay of secondary stroke preventa
Externí odkaz:
https://doaj.org/article/5f82a26971f74550a4d586cf0a84660b
Autor:
Bronwyn Tunnage, Lisa J. Woodhouse, Mark Dixon, Craig Anderson, Sandeep Ankolekar, Jason Appleton, Lesley Cala, Timothy England, Kailash Krishnan, Diane Havard, Grant Mair, Keith Muir, Steve Phillips, John Potter, Christopher Price, Marc Randall, Thompson G. Robinson, Christine Roffe, Else Sandset, Niro Siriwardena, Polly Scutt, Joanna M. Wardlaw, Nikola Sprigg, Philip M. Bath, on behalf of the RIGHT-2 Investigators
Publikováno v:
BMC Emergency Medicine, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Prehospital stroke trials will inevitably recruit patients with non-stroke conditions, so called stroke mimics. We undertook a pre-specified analysis to determine outcomes in patients with mimics in the second Rapid Intervention w
Externí odkaz:
https://doaj.org/article/6a8c62c48ff74ee7a3ce59ad498c399a