Výsledky vyhledávání - "Nikol Jankovska"

Akademický článek

Biomarkers Analysis and Clinical Manifestations in Comorbid Creutzfeldt–Jakob Disease: A Retrospective Study in 215 Autopsy Cases

Autor: Nikol Jankovska, Robert Rusina, Jiri Keller, Jaromir Kukal, Magdalena Bruzova, Eva Parobkova, Tomas Olejar, Radoslav Matej

Publikováno v: Biomedicines, Vol 10, Iss 3, p 680 (2022)

Creutzfeldt–Jakob disease (CJD), the most common human prion disorder, may occur as “pure” neurodegeneration with isolated prion deposits in the brain tissue; however, comorbid cases with different concomitant neurodegenerative diseases have be

Externí odkaz: https://doaj.org/article/12872e8d15424f4893994aa58940fd61

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Akademický článek

Human Prion Disorders: Review of the Current Literature and a Twenty-Year Experience of the National Surveillance Center in the Czech Republic

Autor: Nikol Jankovska, Robert Rusina, Magdalena Bruzova, Eva Parobkova, Tomas Olejar, Radoslav Matej

Publikováno v: Diagnostics, Vol 11, Iss 10, p 1821 (2021)

Human prion disorders (transmissible spongiform encephalopathies, TSEs) are unique, progressive, and fatal neurodegenerative diseases caused by aggregation of misfolded prion protein in neuronal tissue. Due to the potential transmission, human TSEs a

Externí odkaz: https://doaj.org/article/760cf9e50f9e4926824bcfb6b79e2ff8

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Akademický článek

Molecular Pathology of ALS: What We Currently Know and What Important Information Is Still Missing

Autor: Nikol Jankovska, Radoslav Matej

Publikováno v: Diagnostics, Vol 11, Iss 8, p 1365 (2021)

Despite an early understanding of amyotrophic lateral sclerosis (ALS) as a disease affecting the motor system, including motoneurons in the motor cortex, brainstem, and spinal cord, today, many cases involving dementia and behavioral disorders are re

Externí odkaz: https://doaj.org/article/8ca6951ee94449249c7989892f8e31a5

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Different Morphology of Neuritic Plaques in the Archicortex of Alzheimer’s Disease with Comorbid Synucleinopathy: A Pilot Study

Autor: Jaromir Kukal, Nikol Jankovska, Radoslav Matej, Tomas Olejar

Publikováno v: Current Alzheimer Research. 17:948-958

Background: Bulbous neuritic changes in neuritic plaques have already been described, and their possible effect on the clinical course of the disease has been discussed. Objective: In our study, we focused on the location and density of these structu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0123305906ec2690414d556ec85ec1
https://doi.org/10.2174/1875692117999201215162043

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Extracellular Prion Protein Aggregates in Nine Gerstmann–Sträussler–Scheinker Syndrome Subjects with Mutation P102L: A Micromorphological Study and Comparison with Literature Data

Autor: Tomas Olejar, Radoslav Matej, Nikol Jankovska

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 13303, p 13303 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13303

Gerstmann–Sträussler–Scheinker syndrome (GSS) is a hereditary neurodegenerative disease characterized by extracellular aggregations of pathological prion protein (PrP) forming characteristic plaques. Our study aimed to evaluate the micromorpholo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33035cb7759434410735efe7f5776af7
https://www.mdpi.com/1422-0067/22/24/13303

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Extracellular Protein Aggregates Colocalization and Neuronal Dystrophy in Comorbid Alzheimer’s and Creutzfeldt–Jakob Disease: A Micromorphological Pilot Study on 20 Brains

Autor: Tomas Olejar, Radoslav Matej, Nikol Jankovska

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 2099, p 2099 (2021)

Alzheimer’s disease (AD) and sporadic Creutzfeldt–Jakob disease (sCJD) are both characterized by extracellular pathologically conformed aggregates of amyloid proteins—amyloid β-protein (Aβ) and prion protein (PrPSc), respectively. To investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414083bfa4bde3ff20cbcada7d6c4da3
http://europepmc.org/articles/PMC7924045

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Human Prion Disorders: Review of the Current Literature and a Twenty-Year Experience of the National Surveillance Center in the Czech Republic

Autor: Tomas Olejar, Magdalena Bruzova, Nikol Jankovska, Eva Parobkova, Radoslav Matej, Robert Rusina

Publikováno v: Diagnostics
Diagnostics, Vol 11, Iss 1821, p 1821 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227adcdc3cb10d1e352fedb6259defda
https://doi.org/10.3390/diagnostics11101821

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Extracellular Amyloid Deposits in Alzheimer’s and Creutzfeldt–Jakob Disease: Similar Behavior of Different Proteins?

Autor: Radoslav Matej, Tomas Olejar, Nikol Jankovska

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 7, p 7 (2021)
International Journal of Molecular Sciences

Neurodegenerative diseases are characterized by the deposition of specific protein aggregates, both intracellularly and/or extracellularly, depending on the type of disease. The extracellular occurrence of tridimensional structures formed by amyloido

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbab6fe7c2c1a44d8e7c29cfb1c292b0
https://doi.org/10.3390/ijms22010007

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