Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Niklas Tötsch"'
Autor:
Neda Rafieiolhosseini, Matthias Killa, Thorben Neumann, Niklas Tötsch, Jean-Noël Grad, Alexander Höing, Thies Dirksmeyer, Jochen Niemeyer, Christian Ottmann, Shirley K. Knauer, Michael Giese, Jens Voskuhl, Daniel Hoffmann
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 18, Iss 1, Pp 1322-1331 (2022)
The 14-3-3 protein family, one of the first discovered phosphoserine/phosphothreonine binding proteins, has attracted interest not only because of its important role in the cell regulatory processes but also due to its enormous number of interactions
Externí odkaz:
https://doaj.org/article/d60fc9a2fd0f4a07b702ee811fd82535
Publikováno v:
BioData Mining, Vol 14, Iss 1, Pp 1-22 (2021)
Abstract Evaluating binary classifications is a pivotal task in statistics and machine learning, because it can influence decisions in multiple areas, including for example prognosis or therapies of patients in critical conditions. The scientific com
Externí odkaz:
https://doaj.org/article/911cd56ee24f47179e672a013ce9dc67
Autor:
Niklas Tötsch, Daniel Hoffmann
Publikováno v:
ACS Omega, Vol 5, Iss 25, Pp 15162-15168 (2020)
Externí odkaz:
https://doaj.org/article/85c02ff562a1430da80103f0d857deee
Autor:
Niklas Tötsch, Daniel Hoffmann
Publikováno v:
PeerJ Computer Science, Vol 7, p e398 (2021)
Classifiers are often tested on relatively small data sets, which should lead to uncertain performance metrics. Nevertheless, these metrics are usually taken at face value. We present an approach to quantify the uncertainty of classification performa
Externí odkaz:
https://doaj.org/article/ce0317b75cc6455789ec6681e6fb630b
Autor:
Daniel Hoffmann, Niklas Tötsch
Publikováno v:
ACS Omega, Vol 5, Iss 25, Pp 15162-15168 (2020)
ACS Omega
ACS Omega
We combine Bayesian data integration with kinetic modeling to rigorously identify reaction mechanisms. This approach forces models to be consistent not only with kinetic measurements but with all available information. We revisit a classic study on t
Autor:
Christian Ottmann, Jean-Noël Grad, Shirley K. Knauer, Neda Rafieiolhosseini, Niklas Tötsch, Daniel Hoffmann, Matthias Killa, Jens Voskuhl, Alexander Höing
The 14-3-3 protein family, one of the first discovered phosphoserine/phosphothreonine binding proteins, has attracted interest not only because of its important role in the cell regulatory processes but also due to its enormous number of interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::419c99e2fad3b60f925fe87e30e32dee
https://doi.org/10.3762/bxiv.2021.11.v1
https://doi.org/10.3762/bxiv.2021.11.v1
Autor:
Daniel Hoffmann, Niklas Tötsch, Jean-Noël Grad, Daniel Smolin, Markus Kaiser, Jürgen Linders, Thomas Schrader, Michael Kirsch, Farnusch Kaschani
Self-cleavage of proteins is an important natural process that is difficult to control externally. Recently a new mechanism for the accelerated autolysis of trypsin was discovered involving polyanionic template polymers; however it relies on unspecif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8484d32fe2dd886f0a82919c5b1a62bd
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85089665124
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85089665124
Autor:
Mark A. Johnson, Aaron J. Bloomfield, Hans-Jörg Krüger, Niklas Tötsch, Subrata Ghosh, Fabian S. Menges, Stephanie M. Craig
Publikováno v:
Angewandte Chemie. 128:1304-1307
We describe a systematic method for the preparation and spectroscopic characterization of a CO2 molecule coordinated to an activated bisphenoidal nickel(I) compound containing a tetraazamacrocyclic ligand in the gas phase. The resulting complex was t
p-Tolyl(trifluoromethyl)carbene and the related fluorenyl(trifluoromethyl)carbene were synthesized in solid argon and characterized by IR, UV-vis, and electron paramagnetic resonance spectroscopy as well as by quantum mechanical calculations. The car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4cf89fa67008150eed33b0df5c2b7c
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85028920987
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85028920987
Autor:
Fabian S. Menges, Niklas Tötsch, Joseph A. Fournier, Mark A. Johnson, Stephanie M. Craig, Arron B. Wolk
Publikováno v:
Proceedings of the 70th International Symposium on Molecular Spectroscopy.