Zobrazeno 1 - 10
of 263
pro vyhledávání: '"Niklas K, Björkström"'
Autor:
Kaisa Hofwimmer, Joyce de Paula Souza, Narmadha Subramanian, Milica Vujičić, Leila Rachid, Hélène Méreau, Cheng Zhao, Erez Dror, Emelie Barreby, Niklas K. Björkström, Ingrid Wernstedt Asterholm, Marianne Böni-Schnetzler, Daniel T. Meier, Marc Y. Donath, Jurga Laurencikiene
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Postprandial IL-1β surges are predominant in the white adipose tissue (WAT), but its consequences are unknown. Here, we investigate the role of IL-1β in WAT energy storage and show that adipocyte-specific deletion of IL-1 receptor 1 (IL1R1
Externí odkaz:
https://doaj.org/article/ba5db9b693c1401681bcd5953d8aed76
Autor:
Christian Niehaus, Sebastian Klein, Benedikt Strunz, Erich Freyer, Benjamin Maasoumy, Heiner Wedemeyer, Niklas K. Björkström, Anke R.M. Kraft, Markus Cornberg
Publikováno v:
JHEP Reports, Vol 6, Iss 6, Pp 101074- (2024)
Background & Aims: Patients with advanced cirrhosis often develop hepatic decompensation, which is accompanied by systemic inflammation and may eventually lead to acute-on-chronic liver failure. One important cause of systemic hyperinflammation is a
Externí odkaz:
https://doaj.org/article/25f9b1d137a244d5b0daaf623a9be220
Autor:
Marte Holmberg, Hans Christian D. Aass, Olav Dalgard, Ellen Samuelsen, Dan Sun, Niklas K. Björkström, Asgeir Johannessen, Dag Henrik Reikvam
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Patients with HBeAg-negative chronic hepatitis B may experience an immune response after stopping nucleos(t)ide analogue (NA)therapy, which may potentially trigger HBsAg loss or off-therapy sustained viral control. The immunological mechanis
Externí odkaz:
https://doaj.org/article/70606df5208e42f38a5470d163d0ab66
Autor:
Bonnie Bengtsson, Christopher Maucourant, Johan K Sandberg, Niklas K Björkström, Hannes Hagström
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0294695 (2024)
Background and aimsInfection is a serious complication in patients with cirrhosis. Mucosal-associated invariant T (MAIT) cells are involved in the immune defense against infections and known to be impaired in several chronic conditions, including cir
Externí odkaz:
https://doaj.org/article/75241782ae954a029ae9471c7474e565
Autor:
Laura M. Palma Medina, Haris Babačić, Majda Dzidic, Åsa Parke, Marina Garcia, Kimia T. Maleki, Christian Unge, Magda Lourda, Egle Kvedaraite, Puran Chen, Jagadeeswara Rao Muvva, Martin Cornillet, Johanna Emgård, Kirsten Moll, Karolinska K. I./K. COVID-19 Study Group, Jakob Michaëlsson, Malin Flodström-Tullberg, Susanna Brighenti, Marcus Buggert, Jenny Mjösberg, Karl-Johan Malmberg, Johan K. Sandberg, Sara Gredmark-Russ, Olav Rooyackers, Mattias Svensson, Benedict J. Chambers, Lars I. Eriksson, Maria Pernemalm, Niklas K. Björkström, Soo Aleman, Hans-Gustaf Ljunggren, Jonas Klingström, Kristoffer Strålin, Anna Norrby-Teglund
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-19 (2023)
Abstract Background COVID-19 remains a major public health challenge, requiring the development of tools to improve diagnosis and inform therapeutic decisions. As dysregulated inflammation and coagulation responses have been implicated in the pathoph
Externí odkaz:
https://doaj.org/article/d9502f7d22f248878bad4b825dd78148
Autor:
Hannes Jansson, Martin Cornillet, Dan Sun, Iva Filipovic, Christian Sturesson, Colm J. O’Rourke, Jesper B. Andersen, Niklas K. Björkström, Ernesto Sparrelid
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionSystemic inflammatory markers have been validated as prognostic factors for patients with biliary tract cancer (BTC). The aim of this study was to evaluate specific immunologic prognostic markers and immune responses by analyzing preopera
Externí odkaz:
https://doaj.org/article/c3e7658b689242a6818b06ca97885cc3
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Background and aimsNon-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease. The prognosis may vary from simple steatosis to more severe outcomes such as nonalcoholic steatohepatitis (NASH), liver cirrhosis, and hepatocellul
Externí odkaz:
https://doaj.org/article/16a52c2c1efd4aefb802ca99e201fe8a
Autor:
Angelica Cuapio, Caroline Boulouis, Iva Filipovic, David Wullimann, Tobias Kammann, Tiphaine Parrot, Puran Chen, Mira Akber, Yu Gao, Quirin Hammer, Benedikt Strunz, André Pérez Potti, Olga Rivera Ballesteros, Joshua Lange, Jagadeeswara Rao Muvva, Peter Bergman, Ola Blennow, Lotta Hansson, Stephan Mielke, Piotr Nowak, Gunnar Söderdahl, Anders Österborg, C. I. Edvard Smith, Gordana Bogdanovic, Sandra Muschiol, Fredrika Hellgren, Karin Loré, Michal J. Sobkowiak, Giorgio Gabarrini, Katie Healy, Margaret Sällberg Chen, Evren Alici, Niklas K. Björkström, Marcus Buggert, Per Ljungman, Johan K. Sandberg, Soo Aleman, Hans-Gustaf Ljunggren
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-12 (2022)
Abstract Adaptive immune responses have been studied extensively in the course of mRNA vaccination against COVID-19. Considerably fewer studies have assessed the effects on innate immune cells. Here, we characterized NK cells in healthy individuals a
Externí odkaz:
https://doaj.org/article/385ad681ef5c4016a17b2e4b36257493
Autor:
Martha E. Haugstøyl, Martin Cornillet, Kristina Strand, Natalie Stiglund, Dan Sun, Laurence Lawrence-Archer, Iren D. Hjellestad, Christian Busch, Gunnar Mellgren, Niklas K. Björkström, Johan Fernø
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Natural killer (NK) cells have emerged as key mediators of obesity-related adipose tissue inflammation. However, the phenotype of NK cell subsets residing in human adipose tissue are poorly defined, preventing a detailed understanding of their role i
Externí odkaz:
https://doaj.org/article/4425378e299f4445bd9f93ddad9f75c0
Autor:
Martin Cornillet, Helen Zemack, Hannes Jansson, Ernesto Sparrelid, Ewa Ellis, Niklas K. Björkström
Publikováno v:
Cells, Vol 12, Iss 12, p 1663 (2023)
Alpha-1 antitrypsin deficiency (A1ATD) is underdiagnosed and associated with liver diseases. Here, we genotyped 130 patients with biliary tract cancer (BTC) scheduled for liver resection and found A1ATD in 10.8% of the patients. A1ATD was found in al
Externí odkaz:
https://doaj.org/article/c88495c91488457fb8edcf59b2c3f1bc