Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Niklas Daniel Åke Persson"'
Publikováno v:
Persson, N D Å, Uusalo, P, Nedergaard, M, Lohela, T J & Lilius, T O 2022, ' Could dexmedetomidine be repurposed as a glymphatic enhancer? ', Trends in Pharmacological Sciences, vol. 43, no. 12, pp. 1030-1040 . https://doi.org/10.1016/j.tips.2022.09.007
Cerebrospinal fluid (CSF) flows through the central nervous system (CNS) via the glymphatic pathway to clear the interstitium of metabolic waste. In preclinical studies, glymphatic fluid flow rate increases with low central noradrenergic tone and slo
Autor:
Evan Hunter Stanton, Niklas Daniel Åke Persson, Ryszard Stefan Gomolka, Tuomas Lilius, Björn Sigurðsson, Hedok Lee, Anna Lenice Ribeiro Xavier, Helene Benveniste, Maiken Nedergaard, Yuki Mori
Publikováno v:
Magnetic Resonance in Medicine. 85:3326-3342
Purpose Dynamic contrast-enhanced MRI (DCE-MRI) represents the only available approach for glymphatic cerebrospinal fluid (CSF) flow 3D mapping in the brain of living animals and humans. The purpose of this study was to develop a novel DCE-MRI protoc