Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Niklas Boknäs"'
Autor:
Abigail S. McGovern, Pia Larsson, Volga Tarlac, Natasha Setiabakti, Leila Shabani Mashcool, Justin R. Hamilton, Niklas Boknäs, Juan Nunez-Iglesias
Publikováno v:
Platelets, Vol 35, Iss 1 (2024)
AbstractThe last decade has seen increasing use of advanced imaging techniques in platelet research. However, there has been a lag in the development of image analysis methods, leaving much of the information trapped in images. Herein, we present a r
Externí odkaz:
https://doaj.org/article/51906f3a1fa541c297ef889cc4fb0c1e
Publikováno v:
Platelets, Vol 34, Iss 1 (2023)
Pharmacological inhibition of the platelet ADP-receptor P2Y12 is a cornerstone in the prevention of atherothrombotic events in adult patients with acute coronary syndrome (ACS). Thienopyridines such as clopidogrel and prasugrel exert their antithromb
Externí odkaz:
https://doaj.org/article/e760f2e4c67d4a47b645b869275587b4
Autor:
Suryyani Deb, Niklas Boknäs, Clara Sjöström, Anjana Tharmakulanathan, Kourosh Lotfi, Sofia Ramström
Publikováno v:
Cancer Medicine, Vol 9, Iss 1, Pp 313-323 (2020)
Abstract Since their introduction, tyrosine kinase inhibitors (TKIs, eg, imatinib, nilotinib, dasatinib, bosutinib, ponatinib) have revolutionized the treatment of chronic myeloid leukemia (CML). However, long‐term treatment with TKIs is associated
Externí odkaz:
https://doaj.org/article/51984e92b7a34ea9a67fc4e7d29d2f61
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Heparin and bivalirudin are widely used as anticoagulants in the setting of acute thrombosis. In this study, we investigated how these drugs affect the ability of thrombin to generate a prothrombotic platelet response via activation of the protease-a
Externí odkaz:
https://doaj.org/article/fc670f561f194259b128000304fbb285
Publikováno v:
Platelets, Vol 29, Iss 5, Pp 512-519 (2018)
Platelet function disorders (PFDs) are common in patients with mild bleeding disorders (MBDs), yet the significance of laboratory findings suggestive of a PFD remain unclear due to the lack of evidence for a clinical correlation between the test resu
Externí odkaz:
https://doaj.org/article/eaaf4f9599e540e285b5e00b433cab46
Autor:
Ankit S. Macwan, Niklas Boknäs, Maria P. Ntzouni, Sofia Ramström, Jonathan M. Gibbins, Lars Faxälv, Tomas L. Lindahl
Publikováno v:
Haematologica, Vol 104, Iss 7 (2019)
As platelet activation is an irreversible and potentially harmful event, platelet stimulatory signaling must be tightly regulated to ensure the filtering-out of inconsequential fluctuations of agonist concentrations in the vascular milieu. Herein, we
Externí odkaz:
https://doaj.org/article/7411bea6610746999c8d5244d83d9193
Autor:
Abigail S McGovern, Pia Larsson, Volga Tarlac, Juan Nunez-Iglesias, Stephen Cody, Lars Faxälv, Justin R Hamilton, Niklas Boknäs
Publikováno v:
Blood. 140:1662-1663
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6dcd70467a7c73e0ba7113379a5e244
https://doi.org/10.1182/blood-2022-168838
https://doi.org/10.1182/blood-2022-168838
Autor:
Niklas Boknäs, Cia Laine, Andreas Hillarp, Ankit S. Macwan, Kerstin M. Gustafsson, Tomas L. Lindahl, Margareta Holmström
Publikováno v:
Thrombosis research. 213
In this single-center cohort study, we applied a panel of laboratory markers to characterize hemostatic function in 217 consecutive patients that underwent testing for COVID-19 as they were admitted to Linkoping ¨ University Hospital between April a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe03cf8532946f8db26655e2116f4c7f
https://pubmed.ncbi.nlm.nih.gov/35316719
https://pubmed.ncbi.nlm.nih.gov/35316719
Publikováno v:
Biochemical Society Transactions. 44:35-39
Platelet-derived polyphosphates (polyP), stored in dense granule and released upon platelet activation, have been claimed to enhance thrombin activation of coagulation factor XI (FXI) and to activate FXII directly. The latter claim is controversial a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::673117f78038f15f37aa1b93e36531c4
https://doi.org/10.1042/bst20150220
https://doi.org/10.1042/bst20150220
Autor:
Ankit S, Macwan, Niklas, Boknäs, Maria P, Ntzouni, Sofia, Ramström, Jonathan M, Gibbins, Lars, Faxälv, Tomas L, Lindahl
Publikováno v:
Haematologica
As platelet activation is an irreversible and potentially harmful event, platelet stimulatory signaling must be tightly regulated to ensure the filtering-out of inconsequential fluctuations of agonist concentrations in the vascular milieu. Herein, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::440c0611959ee03b19ffc74fd90dabee
https://pubmed.ncbi.nlm.nih.gov/30630981
https://pubmed.ncbi.nlm.nih.gov/30630981