Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Niklas A. Schmacke"'
Autor:
Meiyue Wang, Heinrich Flaswinkel, Abhinav Joshi, Matteo Napoli, Sergi Masgrau-Alsina, Julia M. Kamper, Antonia Henne, Alexander Heinz, Marleen Berouti, Niklas A. Schmacke, Karsten Hiller, Elisabeth Kremmer, Benedikt Wefers, Wolfgang Wurst, Markus Sperandio, Jürgen Ruland, Thomas Fröhlich, Veit Hornung
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Innate immune responses are linked to key metabolic pathways, yet the proximal signaling events that connect these systems remain poorly understood. Here we show that phosphofructokinase 1, liver type (PFKL), a rate-limiting enzyme of glycol
Externí odkaz:
https://doaj.org/article/1927e1207bb440388975d052a11a059b
Autor:
Niklas A. Schmacke, Fionan O’Duill, Moritz M. Gaidt, Inga Szymanska, Julia M. Kamper, Jonathan L. Schmid-Burgk, Sophia C. Mädler, Timur Mackens-Kiani, Tatsuya Kozaki, Dhruv Chauhan, Dennis Nagl, Che A. Stafford, Hartmann Harz, Adrian L. Fröhlich, Francesca Pinci, Florent Ginhoux, Roland Beckmann, Matthias Mann, Heinrich Leonhardt, Veit Hornung
Publikováno v:
Immunity
The NLRP3 inflammasome plays a central role in antimicrobial defense as well as in the context of sterile inflammatory conditions. NLRP3 activity is governed by two independent signals: the first signal primes NLRP3, rendering it responsive to the se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20fe4f997deab4854711117bc7a9c46
https://europepmc.org/articles/PMC7614333/
https://europepmc.org/articles/PMC7614333/
Autor:
Veit Hornung, Patricia M. Spaeth, Benedikt Sandmeyer, Kristina Adorjan, Tonina T. Mueller, Matthias Klein, Jochen Rech, Hella Thun, Burak Karakoc, Niklas A. Schmacke, Andreas Osterman, Philipp Kressirer, Peter Falkai, Oliver T. Keppler, Lars Kaderali, Paul R. Wratil, Marcel Stern, Mira Zeilberger, Tobias Weinberger, B. Grabein, Julia Reinbold, Manuel Albanese, Julius Steffen
Publikováno v:
Infection
Purpose To determine risk factors for coronavirus disease 2019 (COVID-19) in healthcare workers (HCWs), characterize symptoms, and evaluate preventive measures against SARS-CoV-2 spread in hospitals. Methods In a cross-sectional study conducted betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c5cfcb41dd03c81d94a600c8a69be04
https://doi.org/10.1007/s15010-021-01672-z
https://doi.org/10.1007/s15010-021-01672-z
Autor:
Annkristin Heine, Stefanie Andrea Erika Held, Jonas Schulte-Schrepping, Julia Friederike Andrea Wolff, Kathrin Klee, Thomas Ulas, Niklas Arndt Schmacke, Solveig Nora Daecke, Kati Riethausen, Joachim L. Schultze, Peter Brossart
Publikováno v:
OncoImmunology, Vol 6, Iss 4 (2017)
Myeloid-derived suppressor cells (MDSC) are critical in regulating immune responses by suppressing antigen presenting cells (APC) and T cells. We previously observed that incubation of peripheral blood monocytes with interleukin (IL)-10 during their
Externí odkaz:
https://doaj.org/article/05729484c95e41738353d29a559913f2
Autor:
Manuel, Albanese, Adrian, Ruhle, Jennifer, Mittermaier, Ernesto, Mejías-Pérez, Madeleine, Gapp, Andreas, Linder, Niklas A, Schmacke, Katharina, Hofmann, Alexandru A, Hennrich, David N, Levy, Andreas, Humpe, Karl-Klaus, Conzelmann, Veit, Hornung, Oliver T, Fackler, Oliver T, Keppler
Publikováno v:
Nature methods. 19(1)
CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c653f3b52fc9afd40225f6a86eca6968
https://pubmed.ncbi.nlm.nih.gov/34949808
https://pubmed.ncbi.nlm.nih.gov/34949808
Autor:
Veit Hornung, Niklas A. Schmacke
Publikováno v:
Nature. 581:266-267
Toll-like receptors can initiate an immune response when they detect signs of a viral or microbial threat. New insight into how such receptor activation drives defence programs should aid our efforts to understand autoimmune diseases. Key adaptor pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::347faa21eff955cfef1e50b24a0151f9
https://doi.org/10.1038/d41586-020-01336-2
https://doi.org/10.1038/d41586-020-01336-2
Autor:
Kathrin Klee, Peter Brossart, Solveig Nora Daecke, Joachim L. Schultze, Annkristin Heine, Kati Riethausen, Stefanie Andrea Erika Held, Julia Friederike Andrea Wolff, Niklas Arndt Schmacke, Thomas Ulas, Jonas Schulte-Schrepping
Publikováno v:
OncoImmunology 6(4), e1295203 (2017). doi:10.1080/2162402X.2017.1295203
OncoImmunology, Vol 6, Iss 4 (2017)
OncoImmunology, Vol 6, Iss 4 (2017)
Myeloid-derived suppressor cells (MDSC) are critical in regulating immune responses by suppressing antigen presenting cells (APC) and T cells. We previously observed that incubation of peripheral blood monocytes with interleukin (IL)-10 during their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4adf5c2da146aa7174627de1fa817692
https://pub.dzne.de/record/139232
https://pub.dzne.de/record/139232