Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Niklas, Reimer"'
Autor:
Anke Fähnrich, Zhala Gasimova, Yamil Maluje, Fabian Ott, Helen Sievert, Stephanie Fliedner, Niklas Reimer, Axel Künstner, Niklas Gebauer, Maxim Kebenko, Nikolas von Bubnoff, Jutta Kirfel, Verena-Wilbeth Sailer, Christoph Röcken, Bjoern Konukiewitz, Wolfram Klapper, Alex Frydrychowicz, Sam Mogadas, Gerdt Huebner, Hauke Busch, Cyrus Khandanpour
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Tenosynovial giant cell tumor (TGCT) is a rare type of tumor that originates from the synovium of joints and tendon sheaths. It is characterized by recurring genetic abnormalities, often involving the CSF1 gene. Common symptoms include pain and swell
Externí odkaz:
https://doaj.org/article/40b1b72d680f47c2a37a910d9ae3158d
Autor:
Iryna Manuilova, Jan Bossenz, Annemarie Bianka Weise, Dominik Boehm, Cosima Strantz, Philipp Unberath, Niklas Reimer, Patrick Metzger, Thomas Pauli, Silke D Werle, Susann Schulze, Sonja Hiemer, Arsenij Ustjanzew, Hans A Kestler, Hauke Busch, Benedikt Brors, Jan Christoph
Publikováno v:
JMIR Research Protocols, Vol 13, p e58705 (2024)
BackgroundUnderstanding the similarities of patients with cancer is essential to advancing personalized medicine, improving patient outcomes, and developing more effective and individualized treatments. It enables researchers to discover important pa
Externí odkaz:
https://doaj.org/article/ee8f1cc375034ca5ac0d58a630db6022
Autor:
Christopher Renner, Niklas Reimer, Jan Christoph, Hauke Busch, Patrick Metzger, Melanie Boerries, Arsenij Ustjanzew, Dominik Boehm, Philipp Unberath
Publikováno v:
JMIR Medical Informatics, Vol 11, p e50017 (2023)
BackgroundIn molecular tumor boards (MTBs), patients with rare or advanced cancers are discussed by a multidisciplinary team of health care professionals. Software support for MTBs is lacking; in particular, tools for preparing and documenting MTB th
Externí odkaz:
https://doaj.org/article/bc23258d19c24846b4ee498076b1b64c
Autor:
Hanno M. Witte, Anke Fähnrich, Axel Künstner, Jörg Riedl, Stephanie M. J. Fliedner, Niklas Reimer, Nadine Hertel, Nikolas von Bubnoff, Veronica Bernard, Hartmut Merz, Hauke Busch, Alfred Feller, Niklas Gebauer
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionHematologic malignancies are currently underrepresented in multidisciplinary molecular-tumor-boards (MTB). This study assesses the potential of precision-oncology in primary-refractory plasmablastic-lymphoma (prPBL), a highly lethal blood
Externí odkaz:
https://doaj.org/article/d776783ddf504759bee0582b081ecc06
Autor:
Boerries, Patrick Metzger, Maria Elena Hess, Andreas Blaumeiser, Thomas Pauli, Vincent Schipperges, Ralf Mertes, Jan Christoph, Philipp Unberath, Niklas Reimer, Raphael Scheible, Anna L. Illert, Hauke Busch, Geoffroy Andrieux, Melanie
Publikováno v:
Cancers; Volume 15; Issue 13; Pages: 3456
(1) Background: Next-generation sequencing (NGS) of patients with advanced tumors is becoming an established method in Molecular Tumor Boards. However, somatic variant detection, interpretation, and report generation, require in-depth knowledge of bo
Searching of Clinical Trials Made Easier in cBioPortal Using Patients' Genetic and Clinical Profiles
Autor:
Philipp, Unberath, Lukas, Mahlmeister, Niklas, Reimer, Hauke, Busch, Melanie, Boerries, Jan, Christoph
Publikováno v:
Applied Clinical Informatics. 13:363-369
Background Molecular tumor boards (MTBs) cope with the complexity of an increased usage of genome sequencing data in cancer treatment. As for most of these patients, guideline-based therapy options are exhausted, finding matching clinical trials is c
Autor:
Lorenz Bastian, Alina M. Hartmann, Thomas Beder, Sonja Hänzelmann, Jan Kässens, Miriam Bultmann, Marc P. Hoeppner, Sören Franzenburg, Michael Wittig, Andre Franke, Inga Nagel, Malte Spielmann, Niklas Reimer, Hauke Busch, Stefan Schwartz, Björn Steffen, Andreas Viardot, Konstanze Döhner, Mustafa Kondakci, Gerald Wulf, Knut Wendelin, Andrea Renzelmann, Alexander Kiani, Heiko Trautmann, Martin Neumann, Nicola Gökbuget, Monika Brüggemann, Claudia D. Baldus
Publikováno v:
Leukemia. 36(6)
Autor:
Niklas, Reimer, Philipp, Unberath, Hauke, Busch, Melanie, Börries, Patrick, Metzger, Arsenij, Ustjanzew, Christopher, Renner, Hans-Ulrich, Prokosch, Jan, Christoph
Publikováno v:
Studies in health technology and informatics. 287
In Molecular Tumor Boards (MTBs), therapy recommendations for cancer patients are discussed. To aid decision-making based on the patient's molecular profile, the research platform cBioPortal was extended based on users' requirements. Additionally, a
Autor:
Niklas Reimer, Patrick Metzger, Philipp Unberath, Hauke Busch, Jan Christoph, Christopher Renner, Arsenij Ustjanzew, Hans-Ulrich Prokosch, Melanie Börries
In Molecular Tumor Boards (MTBs), therapy recommendations for cancer patients are discussed. To aid decision-making based on the patient’s molecular profile, the research platform cBioPortal was extended based on users’ requirements. Additionally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd3d77f320d78f0a07ba2de70c0366ca
https://doi.org/10.3233/shti210833
https://doi.org/10.3233/shti210833
Publikováno v:
Studies in health technology and informatics. 281
cBioPortal is a commonly used data warehousing solution for genomic cancer studies. The software is being extended for patient care application in a molecular tumor board by the MIRACUM consortium within the Medical Informatics Initiative Germany. A