Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Niklas, Lindegardh"'
Autor:
Nelson Lee, Chun Kwok Wong, Paul K.S. Chan, Niklas Lindegardh, Nicholas J. White, Frederick G. Hayden, Edward H.C. Wong, Ka Shing Wong, Clive S. Cockram, Joseph J.Y. Sung, David S.C. Hui
Publikováno v:
Emerging Infectious Diseases, Vol 16, Iss 1, Pp 139-142 (2010)
We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios >3), and interleukin-6, CXCL10/IP-10, but no eviden
Externí odkaz:
https://doaj.org/article/b4bb3bc4327b4359a1890a2498e068b6
Autor:
Issaka Zongo, Fabrice A Somé, Serge A M Somda, Sunil Parikh, Noel Rouamba, Philip J Rosenthal, Joel Tarning, Niklas Lindegardh, François Nosten, Jean Bosco Ouédraogo
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103200 (2014)
One promising new Artemisinin-based combination therapies (ACTs) is dihydroartemisinin-piperaquine (DHA-PQ). However, the pharmacokinetics of piperaquine and the relationship between drug levels and clinical efficacy are incompletely characterized, p
Externí odkaz:
https://doaj.org/article/bb1f62425529479b81b8055b191c57eb
Autor:
Myat P Kyaw, Myat H Nyunt, Khin Chit, Moe M Aye, Kyin H Aye, Niklas Lindegardh, Joel Tarning, Mallika Imwong, Christopher G Jacob, Charlotte Rasmussen, Jamie Perin, Pascal Ringwald, Myaing M Nyunt
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57689 (2013)
Plasmodium falciparum resistance to artemisinins, the first line treatment for malaria worldwide, has been reported in western Cambodia. Resistance is characterized by significantly delayed clearance of parasites following artemisinin treatment. Arte
Externí odkaz:
https://doaj.org/article/2e3fd44ad3d045eb98e07ffcb7e6c9c9
Autor:
Fatai A. Fehintola, Kimberly K. Scarsi, Qing Ma, Sunil Parikh, Gene D. Morse, Babafemi Taiwo, Ibrahim Tope Akinola, Isaac F. Adewole, Niklas Lindegardh, Aphiradee Phakderaj, Oladosu Ojengbede, Robert L. Murphy, Olusegun O. Akinyinka, Francesca T. Aweeka
Publikováno v:
AIDS Research and Treatment, Vol 2012 (2012)
Background. Nevirapine- (NVP-) based antiretroviral therapy (ART) and artesunate-amodiaquine are frequently coprescribed in areas of HIV and malaria endemicity. We explored the impact of this practice on artesunate and dihydroartemisinin pharmacokine
Externí odkaz:
https://doaj.org/article/8fd88e5f56d5495086c7085b6967a458
Autor:
Heiman F L Wertheim, Pilaipan Puthavathana, Ngoc My Nghiem, H Rogier van Doorn, Trung Vu Nguyen, Hung Viet Pham, Decy Subekti, Syahrial Harun, Suhud Malik, Janet Robinson, Motiur Rahman, Walter Taylor, Niklas Lindegardh, Steve Wignall, Jeremy J Farrar, Menno D de Jong
Publikováno v:
PLoS Medicine, Vol 7, Iss 4, p e1000231 (2010)
Externí odkaz:
https://doaj.org/article/74d135c2efe04c9599236e8f777df10b
Autor:
Rose McGready, Saw Oo Tan, Elizabeth A Ashley, Mupawjay Pimanpanarak, Jacher Viladpai-Nguen, Lucy Phaiphun, Katja Wüstefeld, Marion Barends, Natthapon Laochan, Lily Keereecharoen, Niklas Lindegardh, Pratap Singhasivanon, Nicholas J White, François Nosten
Publikováno v:
PLoS Medicine, Vol 5, Iss 12, p e253 (2008)
To date no comparative trials have been done, to our knowledge, of fixed-dose artemisinin combination therapies (ACTs) for the treatment of Plasmodium falciparum malaria in pregnancy. Evidence on the safety and efficacy of ACTs in pregnancy is needed
Externí odkaz:
https://doaj.org/article/059e6d457e504cdfa78dbba32543c7a1
Autor:
Walter R J Taylor, Bui Nghia Thinh, Giang Thuc Anh, Peter Horby, Heiman Wertheim, Niklas Lindegardh, Menno D de Jong, Kasia Stepniewska, Tran Thuy Hanh, Nguyen Duc Hien, Ngo Minh Bien, Ngo Quy Chau, Annette Fox, Nghiem My Ngoc, Martin Crusat, Jeremy J Farrar, Nicholas J White, Nguyen Hong Ha, Trinh Thi Lien, Nguyen Vu Trung, Nicholas Day, Nguyen Gia Binh
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3410 (2008)
In the absence of a parenteral drug, oral oseltamivir is currently recommended by the WHO for treating H5N1 influenza. Whether oseltamivir absorption is adequate in severe influenza is unknown. We measured the steady state, plasma concentrations of n
Externí odkaz:
https://doaj.org/article/5eef17a2ae3243e6be454a4608a846a9
Autor:
Jordan W. Tappero, Joel Tarning, Shelley A. McCormack, Li Yan, Nancy C. Sambol, François Nosten, Francesca T. Aweeka, Darren J. Creek, Emmanuel Arinaitwe, Sunil Parikh, Victor Bigira, Niklas Lindegardh, Abel Kakuru, Humphrey Wanzira
Publikováno v:
Clinical Pharmacology & Therapeutics. 98:87-95
This prospective trial investigated the population pharmacokinetics of piperaquine, given with dihydroartemisinin to treat uncomplicated malaria in 107 Ugandan children 6 months to 2 years old, an age group previously unstudied. Current weight-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4db1c4b216d2273bcda5739539bcf15
https://doi.org/10.1002/cpt.104
https://doi.org/10.1002/cpt.104
Autor:
Halidou Tinto, Laeticia C. Toe, Coulibaly, Joel Tarning, Innocent Valea, Jean-Pierre Van Geertruyden, Maminata Traore, Geraint Davies, Umberto D'Alessandro, Niklas Lindegardh, Stephen A. Ward
Publikováno v:
The journal of antimicrobial chemotherapy
Objectives Mefloquine/artesunate has recently been developed as a fixed-dose combination, providing a promising rescue/alternative treatment for malaria during pregnancy. However, limited data are available on the effect of pregnancy on its pharmacok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa7bb92307881a39ea453d9c0236997f
https://doi.org/10.1093/jac/dku154
https://doi.org/10.1093/jac/dku154
Autor:
Melvin N. Doster, Genoveffa Franchini, Zhong-Min Ma, Niklas Lindegardh, Monica Vaccari, Claudio Fenizia, Gene M. Shearer, Anna Hryniewicz, Joel Tarning, Christopher J. Miller, Adriano Boasso, Alan L. Landay
Publikováno v:
AIDS research and human retroviruses, vol 30, iss 4
Simian immunodeficiency virus (SIV) infection leads to AIDS in experimentally infected Rhesus macaques similarly to HIV-infected humans. In contrast, SIV infection of natural hosts is characterized by a down-regulation of innate acute responses to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f2b032f597887e9c99300b9c05ccc59
https://doi.org/10.1089/aid.2013.0218
https://doi.org/10.1089/aid.2013.0218