Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nikko P Torres"'
Autor:
Brandon Ho, Ethan J Sanford, Raphael Loll-Krippleber, Nikko P Torres, Marcus B Smolka, Grant W Brown
Publikováno v:
eLife, Vol 12 (2023)
The replication checkpoint is essential for accurate DNA replication and repair, and maintenance of genomic integrity when a cell is challenged with genotoxic stress. Several studies have defined the complement of proteins that change subcellular loc
Externí odkaz:
https://doaj.org/article/237e6447f30d4f348e1780f7a1ef4b11
Autor:
Jacob N. Bonner, Koyi Choi, Xiaoyu Xue, Nikko P. Torres, Barnabas Szakal, Lei Wei, Bingbing Wan, Meret Arter, Joao Matos, Patrick Sung, Grant W. Brown, Dana Branzei, Xiaolan Zhao
Publikováno v:
Cell Reports, Vol 16, Iss 2, Pp 368-378 (2016)
Timely removal of DNA recombination intermediates is critical for genome stability. The DNA helicase-topoisomerase complex, Sgs1-Top3-Rmi1 (STR), is the major pathway for processing these intermediates to generate conservative products. However, the
Externí odkaz:
https://doaj.org/article/603817206fe94d348474bc7447aa4ea4
The replication checkpoint is essential for accurate DNA replication and repair, and maintenance of genomic integrity when a cell is challenged with genotoxic stress. Several studies have defined the complement of proteins that change subcellular loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::118183aac0485dad33c80fccb3b9e532
https://doi.org/10.1101/2022.08.04.502543
https://doi.org/10.1101/2022.08.04.502543
Autor:
Brandon Ho, Raphael Loll-Krippleber, Nikko P. Torres, Andreas Cuny, Fabian Rudolf, Grant W. Brown
Cells respond to environmental stressors by activating programs that result in protein abundance and localization changes. The DNA damage and DNA replication stress responses have been heavily studied and provide exemplars of the roles of protein loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a60ade30b7371c7186385307f60e223
https://doi.org/10.1101/2022.06.08.495346
https://doi.org/10.1101/2022.06.08.495346
Publikováno v:
ASSAY and Drug Development Technologies. 11:299-307
Drug combinations are commonly used in the treatment of a range of diseases such as cancer, AIDS, and bacterial infections. Such combinations are less likely to be thwarted by resistance, and they have the desirable potential to be synergistic. Syner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb71cf6b021090ae19f37aaa3218d776
https://doi.org/10.1089/adt.2012.503
https://doi.org/10.1089/adt.2012.503
Autor:
Scott W. Simpkins, Eva DeRango-Adem, Karen Kubo, Reika Okamoto, Chad L. Myers, Yoko Yashiroda, Abraham A Gebre, Hiroyuki Hirano, Jolanda van Leeuwen, Mami Yoshimura, Hiroyuki Osada, Hiroki Okada, Michael Costanzo, Kerry Andrusiak, Justin Nelson, Sheena C. Li, Grant W. Brown, Katsuhiko Shirahige, Brenda J. Andrews, Jacqueline M. Barber, Erin H. Wilson, Yoshikazu Ohya, Charles Boone, Anastasia Baryshnikova, Raamesh Deshpande, Jeff S. Piotrowski, Marissa A. LeBlanc, Minoru Yoshida, Hamid Safizadeh, Nikko P. Torres
Publikováno v:
Nature chemical biology
Chemical-genetic approaches offer the potential for unbiased functional annotation of chemical libraries. Mutations can alter the response of cells to a compound, revealing chemical-genetic interactions that can elucidate a compound’s mode of actio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d72c31dd65c859651f75e8a6810362
https://pubmed.ncbi.nlm.nih.gov/29161247
https://pubmed.ncbi.nlm.nih.gov/29161247
Autor:
Xiaoyu Xue, Meret Arter, Jaclyn N. Bonner, Patrick Sung, Koyi Choi, Lei Wei, Nikko P. Torres, Grant W. Brown, Bingbing Wan, Barnabas Szakal, Dana Branzei, Joao Matos, Xiaolan Zhao
Publikováno v:
Cell Reports, 16 (2)
Cell reports
Cell Reports, Vol 16, Iss 2, Pp 368-378 (2016)
Cell reports
Cell Reports, Vol 16, Iss 2, Pp 368-378 (2016)
Timely removal of DNA recombination intermediates is critical for genome stability. The DNA helicase-topoisomerase complex, Sgs1-Top3-Rmi1 (STR), is the major pathway for processing these intermediates to generate conservative products. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4c8f27d643f1f22af85336574de9a3
https://hdl.handle.net/20.500.11850/118713
https://hdl.handle.net/20.500.11850/118713
Publikováno v:
Critical reviews in biochemistry and molecular biology. 51(2)
Proteins directly carry out and regulate cellular functions. As a result, changes in protein levels within a cell directly influence cellular processes. Similarly, it is intuitive that the intracellular localization of proteins is a key component of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ca4172189376d7006f020200a57d37
https://pubmed.ncbi.nlm.nih.gov/26893079
https://pubmed.ncbi.nlm.nih.gov/26893079
Autor:
Jeff S Piotrowski, Sheena C Li, Raamesh Deshpande, Scott W Simpkins, Justin Nelson, Yoko Yashiroda, Jacqueline M Barber, Hamid Safizadeh, Erin Wilson, Hiroki Okada, Abraham A Gebre, Karen Kubo, Nikko P Torres, Marissa A LeBlanc, Kerry Andrusiak, Reika Okamoto, Mami Yoshimura, Eva DeRango-Adem, Jolanda van Leeuwen, Katsuhiko Shirahige, Anastasia Baryshnikova, Grant W Brown, Hiroyuki Hirano, Michael Costanzo, Brenda Andrews, Yoshikazu Ohya, Hiroyuki Osada, Minoru Yoshida, Chad L Myers, Charles Boone
Publikováno v:
Nature Chemical Biology. 13:1286-1286
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ecae56e95a0cee6a3c06bce788c7e4
https://doi.org/10.1038/nchembio1217-1286b
https://doi.org/10.1038/nchembio1217-1286b
Autor:
Nikko P, Torres, Grant W, Brown
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1300
High-throughput imaging of yeast cells expressing fluorescent proteins can be used to understand biological pathways in the context of spatial organization. Here we describe a method for imaging yeast cells expressing proteins tagged with green fluor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d4e04adf536f8ddf8e252e9657f0578
https://pubmed.ncbi.nlm.nih.gov/25916702
https://pubmed.ncbi.nlm.nih.gov/25916702