Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nikko Brix"'
Autor:
Leon Emanuel Schnöller, Daniel Piehlmaier, Peter Weber, Nikko Brix, Daniel Felix Fleischmann, Alexander Edward Nieto, Martin Selmansberger, Theresa Heider, Julia Hess, Maximilian Niyazi, Claus Belka, Kirsten Lauber, Kristian Unger, Michael Orth
Publikováno v:
Radiation Oncology, Vol 18, Iss 1, Pp 1-17 (2023)
Abstract Despite intensive basic scientific, translational, and clinical efforts in the last decades, glioblastoma remains a devastating disease with a highly dismal prognosis. Apart from the implementation of temozolomide into the clinical routine,
Externí odkaz:
https://doaj.org/article/c26cb10a07c6433199767a70dbfa306c
Autor:
Leon Emanuel Schnöller, Valerie Albrecht, Nikko Brix, Alexander Edward Nieto, Daniel Felix Fleischmann, Maximilian Niyazi, Julia Hess, Claus Belka, Kristian Unger, Kirsten Lauber, Michael Orth
Publikováno v:
Radiation Oncology, Vol 17, Iss 1, Pp 1-11 (2022)
Abstract Background Inherent resistance to radio/chemotherapy is one of the major reasons for early recurrence, treatment failure, and dismal prognosis of glioblastoma. Thus, the identification of resistance driving regulators as prognostic and/or pr
Externí odkaz:
https://doaj.org/article/f6855d1686394c15a76931f9485152f0
Publikováno v:
Radiation Oncology, Vol 15, Iss 1, Pp 1-12 (2020)
Abstract Background The clonogenic assay is a versatile and frequently used tool to quantify reproductive cell survival in vitro. Current state-of-the-art analysis relies on plating efficiency-based calculations which assume a linear correlation betw
Externí odkaz:
https://doaj.org/article/3133d81f038a4e748fe949c2b4d25198
Autor:
Anne Ernst, Roman Hennel, Julia Krombach, Heidi Kapfhammer, Nikko Brix, Gabriele Zuchtriegel, Bernd Uhl, Christoph A. Reichel, Benjamin Frey, Udo S. Gaipl, Nicolas Winssinger, Senji Shirasawa, Takehiko Sasazuki, Markus Sperandio, Claus Belka, Kirsten Lauber
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Radiotherapy is an essential part of multi-modal cancer therapy. Nevertheless, for certain cancer entities such as colorectal cancer (CRC) the indications of radiotherapy are limited due to anatomical peculiarities and high radiosensitivity of the su
Externí odkaz:
https://doaj.org/article/9ff4f87e978c409a88587d16d172b09f
Autor:
Julia Krombach, Roman Hennel, Nikko Brix, Michael Orth, Ulrike Schoetz, Anne Ernst, Jessica Schuster, Gabriele Zuchtriegel, Christoph A. Reichel, Susanne Bierschenk, Markus Sperandio, Thomas Vogl, Steffen Unkel, Claus Belka, Kirsten Lauber
Publikováno v:
OncoImmunology, Vol 8, Iss 1 (2019)
The major goal of radiotherapy is the induction of tumor cell death. Additionally, radiotherapy can function as in situ cancer vaccination by exposing tumor antigens and providing adjuvants for anti-tumor immune priming. In this regard, the mode of t
Externí odkaz:
https://doaj.org/article/90e51b19a2dc42efa094bb4b946d8d53
Autor:
Nikko Brix, Kirsten Lauber
Publikováno v:
Critical Issues in Head and Neck Oncology ISBN: 9783031231742
Immune checkpoint inhibition has emerged as an integral part of the standard-of-care for head and neck squamous cell carcinoma (HNSCC) in recurrent and/or metastatic stages. Clinical responses are impressive but remain limited to a minority of patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68431f2444cff9677f9845a59d85f88c
https://doi.org/10.1007/978-3-031-23175-9_2
https://doi.org/10.1007/978-3-031-23175-9_2
Publikováno v:
Nat. Protoc. 16, 4963-4991 (2021)
The clonogenic assay measures the capacity of single cells to form colonies in vitro. It is widely used to identify and quantify self-renewing mammalian cells derived from in vitro cultures as well as from ex vivo tissue preparations of different ori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c024866d3ffc69198b7f24ec97a6d7
https://doi.org/10.1038/s41596-021-00615-0
https://doi.org/10.1038/s41596-021-00615-0
Publikováno v:
Internist 61, 682-689 (2020)
HintergrundDas Therapieportfolio für rekurrente und/oder metastasierte Kopf-Hals-Plattenepithelkarzinome („Head and neck squamous cell carcinoma“ [HNSCC]) hat sich mit der klinischen Implementierung der Immuntherapie erweitert: Die einzige molek
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f73b647c9e877c298fbc148e3c30266c
https://doi.org/10.1007/s00108-020-00816-x
https://doi.org/10.1007/s00108-020-00816-x
Autor:
Peter Weber, Martin Selmansberger, Andreas Blutke, Horst Zitzelsberger, Elena Stauffer, Kristian Unger, Kirsten Lauber, Gerald Burgstaller, Claudia Dalke, Theresa Heider, Axel Walch, Nikko Brix
Publikováno v:
Endocr. Relat. Cancer 28, 213-224 (2021)
Thyroid carcinoma incidence rates in western societies are among the fastest rising, compared to all malignant tumors over the past two decades. While risk factors such as age and exposure to ionizing radiation are known, early-state carcinogenic pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbbd55150e7df4833802f55529b56bf1
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=61493
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=61493
Autor:
Nikko Brix, Samaga, Daniel, Hennel, Roman, Gehr, Katharina, Zitzelsberger, Horst, Lauber, Kirsten
Additional file 1: Table S1. Short tandem repeat profiling of cell lines used in this study (Service provided by DSMZ, Braunschweig). Table S2. Overview on cell lines and culture media used in this study. FCS (fetal calf serum), P/S (100 U/ml penicil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e5b9b932e8648c793c4effe23958a8