Impact of Fermentable Protein, by Feeding High Protein Diets, on Microbial Composition, Microbial Catabolic Activity, Gut Health and beyond in Pigs

Autor: Hanlu Zhang, Nikkie van der Wielen, Bart van der Hee, Junjun Wang, Wouter Hendriks, Myrthe Gilbert

Publikováno v: Microorganisms, Vol 8, Iss 11, p 1735 (2020)

In pigs, high protein diets have been related to post-weaning diarrhoea, which may be due to the production of protein fermentation metabolites that were shown to have harmful effects on the intestinal epithelium in vitro. In this review, we discusse

Externí odkaz: https://doaj.org/article/1c41be51e73b4b92b85035f18e568159

Effect of whole foods on the microbial production of tryptophan-derived aryl hydrocarbon receptor agonists in growing pigs

Autor: Zhan Huang, Sonja de Vries, Vincenzo Fogliano, Jerry M. Wells, Nikkie van der Wielen, Edoardo Capuano

Publikováno v: Food Chemistry, 416
Food Chemistry 416 (2023)

Effects of whole foods on the microbial production of tryptophan-derived aryl hydrocarbon receptor (AhR) ligands in the intestine were investigated in a pig model. Ileal digesta and faeces of pigs after feeding of eighteen different foods were analyz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6994ef99306c4d7fad4a1256fc833a
https://research.wur.nl/en/publications/effect-of-whole-foods-on-the-microbial-production-of-tryptophan-d

Comparison of True Ileal Amino Acid Digestibility between Adult Humans and Growing Pigs

Autor: Suzanne M Hodgkinson, Natascha Stroebinger, Nikkie van der Wielen, Marco Mensink, Carlos Montoya, Wouter H Hendriks, Sonja de Vries, Hans H Stein, Paul J Moughan

Publikováno v: The Journal of Nutrition 152 (2022) 7
The Journal of Nutrition, 152(7), 1635-1646

Background: It is not feasible to determine the true ileal amino acid (AA) digestibility of protein sources in humans on a routine basis, and the growing pig has been recommended as an animal model for this purpose but requires further validation.Obj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2414a56f0fb08a0e4702226ea0dd4bf6
https://pubmed.ncbi.nlm.nih.gov/35349701

Blood 15N:13C Enrichment Ratios Are Proportional to the Ingested Quantity of Protein with the Dual-Tracer Approach for Determining Amino Acid Bioavailability in Humans

Autor: Nikkie van der Wielen, Daniel Tomé, Claire Gaudichon, Juliane Calvez, Walter J. J. Gerrits, Nadezda Khodorova, Marco Mensink

Publikováno v: The Journal of Nutrition 150 (2020) 9
The Journal of Nutrition, 150(9), 2346-2352
Journal of Nutrition
Journal of Nutrition, American Society for Nutrition, 2020, 150 (9), pp.2346-2352. ⟨10.1093/jn/nxaa205⟩
The Journal of Nutrition

International audience; Background: Assessment of amino acid bioavailability is of key importance for the evaluation of protein quality; however, measuring ileal digestibility of dietary proteins in humans is challenging. Therefore, a less-invasive d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc072c5cdbaeffe5de319f0d139e3f3e
https://research.wur.nl/en/publications/blood-15n13c-enrichment-ratios-are-proportional-to-the-ingested-q

Nutrient-induced glucagon like peptide-1 release is modulated by serotonin

Autor: Nikkie van der Wielen, Jocelijn Meijerink, Dina Ripken, Henk F. J. Hendriks, Renger F. Witkamp, Heleen M. Wortelboer

Publikováno v: Journal of Nutritional Biochemistry 32 (2016)
Journal of Nutritional Biochemistry, 32, 142-150

Glucagon like peptide-1 (GLP-1) and serotonin are both involved in food intake regulation. GLP-1 release is stimulated upon nutrient interaction with G-protein coupled receptors by enteroendocrine cells (EEC), whereas serotonin is released from enter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7d1efa532427a6de182c67a2ea3eac
https://doi.org/10.1016/j.jnutbio.2016.03.006