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pro vyhledávání: '"Nikki Robert"'
Publikováno v:
Journal of Medical Microbiology. 60:1213-1217
The kinetics of bacterial killing for fidaxomicin and its major metabolite, OP-1118, were investigated against Clostridium difficile strains, including two clinical strains belonging to the restriction endonuclease analysis group BI (ORG 1687 and 169
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:4427-4429
Fidaxomicin (FDX), a narrow-spectrum antibiotic recently shown to be superior to vancomycin in providing sustained clinical response to Clostridium difficile infection, was investigated along with its major metabolite, OP-1118, with regard to their p
Publikováno v:
Antimicrobial agents and chemotherapy. 54(6)
The effects of the inoculum, pH, cation concentrations, and different lots of commercial media on the in vitro susceptibility of Clostridium difficile to fidaxomicin were examined. Of the factors evaluated, only pH alterations influenced the activity