Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nikki P Y Lee"'
Autor:
Wen Wen Xu, Bin Li, Xin Yuan Guan, Sookja K. Chung, Yang Wang, Yim Ling Yip, Simon Y. K. Law, Kin Tak Chan, Nikki P. Y. Lee, Kwok Wah Chan, Li Yan Xu, En Min Li, Sai Wah Tsao, Qing-Yu He, Annie L. M. Cheung
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Cancer cells can affect cancer progression by producing systemic effects. Here, the authors show that IGF2 produced by oesophageal cancer cells increases secretion of VEGF from cancer-associated fibroblasts resulting in systemic mobilization of bone
Externí odkaz:
https://doaj.org/article/42f1fba27d344814905048b4a4333e89
Autor:
John R Lamb, Chunsheng Zhang, Tao Xie, Kai Wang, Bin Zhang, Ke Hao, Eugene Chudin, Hunter B Fraser, Joshua Millstein, Mark Ferguson, Christine Suver, Irena Ivanovska, Martin Scott, Ulrike Philippar, Dimple Bansal, Zhan Zhang, Julja Burchard, Ryan Smith, Danielle Greenawalt, Michele Cleary, Jonathan Derry, Andrey Loboda, James Watters, Ronnie T P Poon, Sheung T Fan, Chun Yeung, Nikki P Y Lee, Justin Guinney, Cliona Molony, Valur Emilsson, Carolyn Buser-Doepner, Jun Zhu, Stephen Friend, Mao Mao, Peter M Shaw, Hongyue Dai, John M Luk, Eric E Schadt
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e20090 (2011)
BackgroundIn hepatocellular carcinoma (HCC) genes predictive of survival have been found in both adjacent normal (AN) and tumor (TU) tissues. The relationships between these two sets of predictive genes and the general process of tumorigenesis and di
Externí odkaz:
https://doaj.org/article/b53d4a768873417aa36a0629f6eecc3f
Autor:
Julja Burchard, Chunsheng Zhang, Angela M Liu, Ronnie T P Poon, Nikki P Y Lee, Kwong‐Fai Wong, Pak C Sham, Brian Y Lam, Mark D Ferguson, George Tokiwa, Ryan Smith, Brendan Leeson, Rebecca Beard, John R Lamb, Lee Lim, Mao Mao, Hongyue Dai, John M Luk
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp n/a-n/a (2010)
Tumorigenesis involves multistep genetic alterations. To elucidate the microRNA (miRNA)–gene interaction network in carcinogenesis, we examined their genome‐wide expression profiles in 96 pairs of tumor/non‐tumor tissues from hepatocellular car
Externí odkaz:
https://doaj.org/article/50bc46a5e0da45ebb7e123909cce0639
Autor:
Nikki P Y, Lee, C Yan, Cheng
Publikováno v:
Advances in experimental medicine and biology. 636
Spermatogenesis is a highly complicated process in which functional spermatozoa (haploid, 1n) are generated from primitive mitotic spermatogonia (diploid, 2n). This process involves the differentiation and transformation of several types of germ cell
Publikováno v:
Biology of reproduction. 73(3)
During spermatogenesis, extensive restructuring of cell junctions takes place in the seminiferous epithelium to facilitate germ cell movement. However, the mechanism that regulates this event remains largely unknown. Recent studies have shown that ni
Autor:
Nikki P Y, Lee, C Yan, Cheng
Publikováno v:
Biology of reproduction. 71(2)
Adaptors are component proteins of junctional complexes in all epithelia, including the seminiferous epithelium of the mammalian testis. They recruit other regulatory and structural proteins to the site of both anchoring junctions (such as cell-cell
Autor:
Nikki P Y, Lee, C Yan, Cheng
Publikováno v:
Biology of reproduction. 70(2)
During spermatogenesis, preleptotene and leptotene spermatocytes, residing in the basal compartment of the seminiferous epithelium, must traverse the blood-testis barrier (BTB) to gain entry to the adluminal compartment for further development at lat
Publikováno v:
Biology of reproduction. 69(2)
Fer kinase is a 94-kDa cytoplasmic cell-cell actin-based adherens junction (AJ)-associated nonreceptor protein tyrosine kinase (PTK) found in multiple epithelia including the testis, whereas FerT kinase (51 kDa) is the truncated testis-specific form
Publikováno v:
Biology of reproduction. 68(2)
Much controversy exists regarding the presence of the cadherin/catenin complex and its intracellular attachment site in the testis, which is the functional unit for actin-based cell-cell adherens junctions (AJs) in multiple epithelia. Furthermore, wh
Autor:
Nikki P Y Lee
Publikováno v:
Journal of Endocrinology; Jan2007, Vol. 192 Issue 1, p17-32, 16p