Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Nikki C. Timmer"'
Autor:
Roberto D. V. S. Morais, Marina Sogorb-González, Citlali Bar, Nikki C. Timmer, M. Leontien Van der Bent, Morgane Wartel, Astrid Vallès
Publikováno v:
Cells, Vol 11, Iss 17, p 2748 (2022)
Huntington’s disease (HD) is a fatal neurodegenerative disorder caused by GAG expansion in exon 1 of the huntingtin (HTT) gene. AAV5-miHTT is an adeno-associated virus serotype 5-based vector expressing an engineered HTT-targeting microRNA (miHTT).
Externí odkaz:
https://doaj.org/article/34d98b50c74a4ed08dd0502971363f9c
Autor:
Eline J ter Steege, Mandy Boer, Nikki C Timmer, Carola ME Ammerlaan, Ji‐Ying Song, Patrick WB Derksen, John Hilkens, Elvira RM Bakker
Publikováno v:
The Journal of pathologyReferences. 258(3)
R-spondins (RSPOs) are influential signaling molecules that promote the Wnt/β-catenin pathway and self-renewal of stem cells. Currently, RSPOs are emerging as clinically relevant oncogenes, being linked to cancer development in multiple organs. Alth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e9d32ac27927dafa28a5c2f53ccc6d
https://pubmed.ncbi.nlm.nih.gov/36106661
https://pubmed.ncbi.nlm.nih.gov/36106661
Autor:
Matthias Schewe, Elvira R. M. Bakker, Nikki C Timmer, Andrea Sacchetti, John Hilkens, Gerjon J. Ikink, Mandy Boer, Ji-Ying Song, Martijn A.J. Koppens
Publikováno v:
Gut, 66(6), 1095-1105. BMJ Publishing Group
Objective The gross majority of colorectal cancer cases results from aberrant Wnt/β-catenin signalling through adenomatous polyposis coli ( APC) or CTNNB1 mutations. However, a subset of human colon tumours harbour, mutually exclusive with APC and C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f33eb0ea6bb8b6b3417fb9ff54cf256
https://hdl.handle.net/1765/96717
https://hdl.handle.net/1765/96717