Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Nikki A Delk"'
Autor:
Haley C Dahl, Mohammed Kanchwala, Shayna E Thomas-Jardin, Amrit Sandhu, Preethi Kanumuri, Afshan F Nawas, Chao Xing, Chenchu Lin, Daniel E Frigo, Nikki A Delk
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0242970 (2020)
Chronic inflammation promotes prostate cancer (PCa) initiation and progression. We previously reported that acute intereluekin-1 (IL-1) exposure represses androgen receptor (AR) accumulation and activity, providing a possible mechanism for IL-1-media
Externí odkaz:
https://doaj.org/article/cc3a459f52fd4a74a232424063330a37
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Cancer cells recruit neutrophils from the bloodstream into the tumor tissue, where these immune cells promote the progression of numerous solid tumors. Studies in mice suggest that blocking neutrophil recruitment to tumors by inhibition of n
Externí odkaz:
https://doaj.org/article/6b19897f60404810a1f315a9ef3e98a3
Supplementary Figure 1 from Altered Subcellular Localization of Tumor-Specific Cyclin E Isoforms Affects Cyclin-Dependent Kinase 2 Complex Formation and Proteasomal Regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a62163abeeafcc0f995ffa772c0ea87
https://doi.org/10.1158/0008-5472.22381280.v1
https://doi.org/10.1158/0008-5472.22381280.v1
Supplementary Figure Legends 1-3 from Altered Subcellular Localization of Tumor-Specific Cyclin E Isoforms Affects Cyclin-Dependent Kinase 2 Complex Formation and Proteasomal Regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae91d74f4ce3f94dc8d589f8aa3f2b3
https://doi.org/10.1158/0008-5472.22381271.v1
https://doi.org/10.1158/0008-5472.22381271.v1
In tumors, alternative translation and posttranslational proteolytic cleavage of full-length cyclin E (EL) produces tumorigenic low molecular weight cyclin E (LMW-E) isoforms that lack a portion of the EL amino-terminus containing a nuclear localizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3a3eea63c0eee2f4d12c879ade5c295
https://doi.org/10.1158/0008-5472.c.6499814.v1
https://doi.org/10.1158/0008-5472.c.6499814.v1
Supplementary Figure 3 from Altered Subcellular Localization of Tumor-Specific Cyclin E Isoforms Affects Cyclin-Dependent Kinase 2 Complex Formation and Proteasomal Regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb6e4d8a1a1e93e1d0a9b9fab166843
https://doi.org/10.1158/0008-5472.22381274.v1
https://doi.org/10.1158/0008-5472.22381274.v1
Supplementary Figure 2 from Altered Subcellular Localization of Tumor-Specific Cyclin E Isoforms Affects Cyclin-Dependent Kinase 2 Complex Formation and Proteasomal Regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524aa30d1836751a9160a1cbe67f771d
https://doi.org/10.1158/0008-5472.22381277.v1
https://doi.org/10.1158/0008-5472.22381277.v1
Autor:
Haley Christine Dahl, Anisha R. Konakalla, Preethi Kanumuri, Basir Mansoor, Anastasia Kelley, Riya Shipurkar, Nikki A. Delk
Publikováno v:
Cancer Research. 83:287-287
Prostate cancer (PCa) is the second most common cause of cancer-related death among American men. Androgen Receptor (AR) transcriptional activity is required for PCa tumor growth. Thus, androgen deprivation therapy (ADT) is a first line PCa therapy.
Autor:
Monica Bautista, Chao Xing, Afshan Fathima Nawas, Nikki A. Delk, Haley Dahl, Shayna E. Thomas-Jardin, Ally Wong, Nicole Roos, Mohammed Kanchwala
Publikováno v:
Cancer Research. 80:P4-07
Breast cancer (BCa) and prostate cancer (PCa) are both hormone receptor (HR) driven cancers with similar etiology, where tumor microenvironment inflammation promotes both BCa and PCa progression. Interleukin-1 (IL-1) is an inflammatory cytokine prese
Autor:
Vanessa Anunobi, Monica Bautista, Kelly Daescu, Nikki A. Delk, Rachel Meade, Haley Dahl, Chao Xing, Felix Bayerl, Ally Wong, Nisha Ghatwai, Ragini Mistry, Mohammed Kanchwala, Afshan Fathima Nawas, Shayna E. Thomas-Jardin
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-15 (2020)
Background Breast (BCa) and prostate (PCa) cancers are hormone receptor (HR)-driven cancers. Thus, BCa and PCa patients are given therapies that reduce hormone levels or directly block HR activity; but most patients eventually develop treatment resis