Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Nikita Pozdeyev"'
Autor:
Madison M. Rose, Veronica L. Espinoza, Katelyn J. Hoff, Laura A. Pike, Vibha Sharma, Marie-Claude Hofmann, Aik Choon Tan, Nikita Pozdeyev, Rebecca E. Schweppe
Publikováno v:
Cancers, Vol 15, Iss 2, p 378 (2023)
Patients with advanced thyroid cancer, including advanced papillary thyroid cancer and anaplastic thyroid cancer (ATC), have low survival rates because of the lack of efficient therapies available that can combat their aggressiveness. A total of 90%
Externí odkaz:
https://doaj.org/article/f96a8b0a8dc0423c8cfa2401f92d2daf
Autor:
Nikita Pozdeyev, Adam Berlinberg, Qiong Zhou, Kelsey Wuensch, Hiroyuki Shibata, William M Wood, Bryan R Haugen
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134901 (2015)
NF-κB signaling plays an important role in tumor cell proliferation, cell survival, angiogenesis, invasion, metastasis and drug/radiation resistance. Combination therapy involving NF-κB pathway inhibition is an attractive strategy for the treatment
Externí odkaz:
https://doaj.org/article/129280423c93467185b7ddc62f3d03e9
Autor:
Martin Barrio, Christopher D. Raeburn, Robert McIntyre, Maria Albuja-Cruz, Bryan R. Haugen, Nikita Pozdeyev
Publikováno v:
Thyroid. 33:547-555
Autor:
Hannah M. Hicks, Nikita Pozdeyev, Sharon B. Sams, Umarani Pugazhenthi, Elise S. Bales, Marie-Claude Hofmann, Logan R. McKenna, Rebecca E. Schweppe
Publikováno v:
Molecular Cancer Research.
Mutations in BRAF are common in advanced papillary and anaplastic thyroid cancer (PTC and ATC). However, BRAF-mutant PTC patients currently lack therapies targeting this pathway. Despite the approved combination of BRAF and MEK1/2 inhibition for pati
Autor:
Nikita Pozdeyev, Manjiri Dighe, Martin Barrio, Christopher Raeburn, Harry Smith, Matthew Fisher, Sameer Chavan, Nicholas Rafaels, Jonathan A. Shortt, Meng Lin, Michael G. Leu, Toshimasa Clark, Carrie Marshall, Bryan R. Haugen, Devika Subramanian, Regeneron Genetics Center, Kristy Crooks, Christopher Gignoux, Trevor Cohen
Evaluating thyroid nodules to rule out malignancy is a very common clinical task. Image-based clinical and machine learning risk stratification schemas rely on the presence of thyroid nodule high-risk sonographic features. However, this approach is l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c854fe7553844c314bc0efc1182c4cc
https://doi.org/10.1101/2023.04.11.23288041
https://doi.org/10.1101/2023.04.11.23288041
Autor:
Lauren Fishbein, Katja Kiseljak-Vassiliades, Margaret E. Wierman, Debbie L. Cohen, Katherine L. Nathanson, Christopher D. Raeburn, Maria Albuja-Cruz, Carrie B. Marshall, Nikita Pozdeyev, Kristin Panwell, Katrina Koc, Nathaniel Alzofon
Metastatic disease in pheochromocytomas and paragangliomas (PCC/PGL) is not well-understood. The Cancer Genome Atlas discovered recurrent MAML3 fusion genes in a subset of tumors that lacked known germline or somatic driver mutations and were associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::674750c2959d14a74db7c61f10663f20
https://doi.org/10.1158/1541-7786.c.6545123.v1
https://doi.org/10.1158/1541-7786.c.6545123.v1
Autor:
Lauren Fishbein, Katja Kiseljak-Vassiliades, Margaret E. Wierman, Debbie L. Cohen, Katherine L. Nathanson, Christopher D. Raeburn, Maria Albuja-Cruz, Carrie B. Marshall, Nikita Pozdeyev, Kristin Panwell, Katrina Koc, Nathaniel Alzofon
MAML3 overexpression has no effect on proliferation or apoptotic signaling. SK-N-SH, QGP-1 and BON-1 transfected with FL or dEx1 MAML3 and showed A) no increase in proliferation by BrdU assay when grown in full serum media for 72 hours and B) no incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce28523047fb39b8d33c486783b1d49
https://doi.org/10.1158/1541-7786.22526531.v1
https://doi.org/10.1158/1541-7786.22526531.v1
Autor:
Bryan R. Haugen, James A. Fagin, Jeffrey A. Knauf, Iñigo Landa, Daniel V. LaBarbera, Philip Reigan, Maria B. Albuja-Cruz, Christopher Raeburn, Umarani Pugazhenthi, Vibha Sharma, Sharon B. Sams, Qiong Zhou, Christopher Korch, Laura A. Pike, Nikita Pozdeyev, Rebecca E. Schweppe
Electropherograms of the CUTC5, CUTC48, CUTC60 and CUTC61 cell line, PDX, and patient samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217c351ac513de8c219d6acdec51feea
https://doi.org/10.1158/1541-7786.22512805.v1
https://doi.org/10.1158/1541-7786.22512805.v1
Autor:
Lauren Fishbein, Katja Kiseljak-Vassiliades, Margaret E. Wierman, Debbie L. Cohen, Katherine L. Nathanson, Christopher D. Raeburn, Maria Albuja-Cruz, Carrie B. Marshall, Nikita Pozdeyev, Kristin Panwell, Katrina Koc, Nathaniel Alzofon
Table S1 has the RNA-Seq sample names and raw counts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11eb49a6bb7f8f13dd356fe0443a1f83
https://doi.org/10.1158/1541-7786.22526510
https://doi.org/10.1158/1541-7786.22526510
Autor:
Bryan R. Haugen, James A. Fagin, Jeffrey A. Knauf, Iñigo Landa, Daniel V. LaBarbera, Philip Reigan, Maria B. Albuja-Cruz, Christopher Raeburn, Umarani Pugazhenthi, Vibha Sharma, Sharon B. Sams, Qiong Zhou, Christopher Korch, Laura A. Pike, Nikita Pozdeyev, Rebecca E. Schweppe
Kinase inhibitor sensitivity of the CUTC cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406fc7355289cc9a71e9fb0294a47e7b
https://doi.org/10.1158/1541-7786.22512796.v1
https://doi.org/10.1158/1541-7786.22512796.v1