Dissecting the Knowns for the Unknowns: Refining the Classification of Genomic Variations in Hematological Diseases By the Clingen Hematological Cancer Taskforce (HCT)

Autor: Yuwen Li, Jason Saliba, Nathan Kopp, Coumarane Mani, Heather E Williams, Wenying Zhang, Jianhua Zhao, Kilannin Krysiak, Arpad Danos, Xiangqiang Shao, Rong He, Panieh Terraf, Nikita N Mehta, Shivani Golem, Jie Liu, Destiney Allen, Chimene Kesserwan, Hagop Kantarjian, Torsten Haferlach, Piers Blombery, Madhu M Ouseph, Ella Thompson, Yiming Zhong, Xiaonan Zhao, Yasmina Jaufeerally Fakim, Sheeja T Pullarkat, Obi L. Griffith, Malachi Griffith, Rashmi Kanagal-Shamanna, Xinjie Xu

Publikováno v: Blood. 140:11810-11811

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7cbe5fdabd6edf8a6906631399b16a5d
https://doi.org/10.1182/blood-2022-170989

Universal germline genetic testing in patients with hematologic malignancies using DNA isolated from nail clippings.

Autor: Ceyhan-Birsoy O; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Fiala E; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY., Rana S; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Sheehan M; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Kennedy J; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Yelskaya Z; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Rai V; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Li Y; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Yang C; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Wong D; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Rijo I; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Casanova J; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Somar J; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Mehta N; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Park H; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Ostafi S; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Arora K; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Padunan A; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Ewalt MD; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Aypar U; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Terraf P; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Misyura M; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Haque S; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY., Behr GG; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY., Haque T; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Sulis M; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY., Geyer MB; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Forlenza C; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY., Thompson MC; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Carlo M; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Latham A; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Liu Y; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Zehir A; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Brannon R; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Berger M; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Diaz LA Jr; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Dogan A; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Ladanyi M; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Petrova-Drus K; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Nafa K; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Offit K; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Arcila M; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Stadler ZK; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY. stadlerz@mskcc.org., Walsh MF; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY. walshm2@mskcc.org., Mandelker D; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY. mandelkd@mskcc.org.

Publikováno v: Haematologica [Haematologica] 2024 Oct 01; Vol. 109 (10), pp. 3383-3390. Date of Electronic Publication: 2024 Oct 01.

Genomic Profiling Reveals Germline Predisposition and Homologous Recombination Deficiency in Pancreatic Acinar Cell Carcinoma.

Autor: Mandelker D; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Marra A; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Zheng-Lin B; Gastrointestinal Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Selenica P; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Blanco-Heredia J; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Zhu Y; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Gazzo A; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Wong D; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Yelskaya Z; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Rai V; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Somar J; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Ostafi S; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Mehta N; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Yang C; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Li Y; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Brown DN; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., da Silva EM; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Pei X; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY., Linkov I; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Terraf P; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Misyura M; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Ceyhan-Birsoy O; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Ladanyi M; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Berger M; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Pareja F; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Stadler Z; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Offit K; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Riaz N; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY., Park W; Gastrointestinal Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Chou J; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY., Capanu M; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY., Koehler M; Repare Therapeutics, Cambridge, MA., Rosen E; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., O'Reilly EM; Gastrointestinal Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Weill Cornell Department of Medicine, Weill Cornell Medicine, New York, NY.; David M. Rubenstein Center for Pancreatic Research, Memorial Sloan Kettering Cancer Center, New York, NY., Reis-Filho JS; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2023 Nov 20; Vol. 41 (33), pp. 5151-5162. Date of Electronic Publication: 2023 Aug 22.

Prevalence and Clinical Implications of Mismatch Repair-Proficient Colorectal Cancer in Patients With Lynch Syndrome.

Autor: Ranganathan M; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Sacca RE; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Trottier M; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Maio A; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Kemel Y; Niehaus Center for Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY., Salo-Mullen E; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Catchings A; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Kane S; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Wang C; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY., Ravichandran V; Niehaus Center for Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY., Ptashkin R; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY., Mehta N; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY., Garcia-Aguilar J; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Surgery, Weill Cornell Medical College, New York, NY., Weiser MR; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Surgery, Weill Cornell Medical College, New York, NY., Donoghue MTA; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY., Berger MF; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY.; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY., Mandelker D; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY., Walsh MF; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Niehaus Center for Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Carlo M; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Niehaus Center for Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Liu YL; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Niehaus Center for Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Cercek A; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Yaeger R; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Saltz L; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Segal NH; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Mendelsohn RB; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Markowitz AJ; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Offit K; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Niehaus Center for Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Shia J; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY., Stadler ZK; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Niehaus Center for Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Latham A; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Niehaus Center for Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY.

Publikováno v: JCO precision oncology [JCO Precis Oncol] 2023 May; Vol. 7, pp. e2200675.

Gene-based Confirmatory Germline Testing Following Tumor-only Sequencing of Prostate Cancer.

Autor: Truong H; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Breen K; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Nandakumar S; Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Sjoberg DD; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kemel Y; Niehaus Center for Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Mehta N; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lenis AT; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Reisz PA; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Carruthers J; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Benfante N; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Joseph V; Niehaus Center for Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Khurram A; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gopalan A; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Fine SW; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Reuter VE; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Vickers AJ; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Birsoy O; Niehaus Center for Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Liu Y; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Walsh M; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Niehaus Center for Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Latham A; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Mandelker D; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Stadler ZK; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Niehaus Center for Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Gastrointestinal Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Pietzak E; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ehdaie B; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Touijer KA; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Laudone VP; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Slovin SF; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Autio KA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Danila DC; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Rathkopf DE; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Eastham JA; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chen Y; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Morris MJ; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Offit K; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Niehaus Center for Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Solit DB; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Scher HI; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Abida W; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Robson ME; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Niehaus Center for Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Carlo MI; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Niehaus Center for Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: carlom@mskcc.org.

Publikováno v: European urology [Eur Urol] 2023 Jan; Vol. 83 (1), pp. 29-38. Date of Electronic Publication: 2022 Sep 15.