Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Nikita Mukhitov"'
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 10, p e1005143 (2016)
Pancreatic islets manage elevations in blood glucose level by secreting insulin into the bloodstream in a pulsatile manner. Pulsatile insulin secretion is governed by islet oscillations such as bursting electrical activity and periodic Ca2+ entry in
Externí odkaz:
https://doaj.org/article/1f761626d24a441cbba37256639a2ee6
Autor:
Dana Neitzey, Christopher A. Voigt, Damen D. Schaak, Matthew James Lucht, Nikita Mukhitov, De-Chuan Meng
Publikováno v:
Metabolic Engineering. 66:308-318
Achieving a high product titer through pathway optimization often requires screening many combinations of enzymes and genetic parts. Typically, a library is screened in a single chassis that is a model or production organism. Here, we present a techn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5043be86fe1e90bf4a9eaca91c5c40ac
https://doi.org/10.1016/j.ymben.2021.01.006
https://doi.org/10.1016/j.ymben.2021.01.006
Autor:
Michael G. Roper, Radha Krishna Murthy Bulusu, Nikita Mukhitov, Jose L. Mendoza-Cortes, Anna G. Adams
Publikováno v:
Analytical Chemistry
Hepatocytes help to maintain glucose homeostasis in response to a variety of signals, including pancreatic hormones such as insulin. Insulin is released from the pancreas with variable dynamics, yet the role that these play in regulating glucose meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ffad592c21652533d6e40b2885dc39
https://doi.org/10.1021/acs.analchem.8b05798
https://doi.org/10.1021/acs.analchem.8b05798
Publikováno v:
Islets
In vivo levels of insulin are oscillatory with a period of ~5–10 minutes, indicating that the islets of Langerhans within the pancreas are synchronized. While the synchronizing factors are still under investigation, one result of this behavior is e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3610c05b02c1afb3cbf138c3e29d3acc
https://doi.org/10.1080/19382014.2019.1581544
https://doi.org/10.1080/19382014.2019.1581544
Autor:
Ross M. McBee, Christian Munck, Christopher A. Voigt, Andrew Kaufman, Tarun Srinivasan, Nikita Mukhitov, Haorong Chen, Damen D. Schaak, Miles Richardson, Max Reitman, De-Chuan Meng, Matt Lucht, Harris H. Wang
Publikováno v:
Nature materials. 21(4)
Engineered living materials could have the capacity to self-repair and self-replicate, sense local and distant disturbances in their environment, and respond with functionalities for reporting, actuation or remediation. However, few engineered living
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778a3fc85cbcccf3f2ad16ed953a44d6
https://pubmed.ncbi.nlm.nih.gov/34857911
https://pubmed.ncbi.nlm.nih.gov/34857911
Autor:
Cristina R. Hofman, Ellen Wadler, Lindsey D. Handley, Liezelle C Lopez, Laura Hunsicker-Wang, Jennifer R. McKinney, Nikita Mukhitov, Cristina S Hamme, Amani D. Piers, Lindsay Euers
Publikováno v:
Protein Science. 27:1942-1954
The Sco protein from Thermus thermophilus has previously been shown to perform a disulfide bond reduction in the Cu(A) protein from T. thermophilus, which is a soluble protein engineered from subunit II of cytochrome ba (3) oxidase that lacks the tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96cbedc12b9312da79c7a8a15dcefa23
https://doi.org/10.1002/pro.3502
https://doi.org/10.1002/pro.3502
Autor:
Nikita Mukhitov, Aaron L. Glieberman, Qihan Liu, Benjamin D. Pope, Douglas A. Melton, John P. Ferrier, Michael G. Roper, Adrian M. Schrell, Kevin Kit Parker, Adrian Buganza Tepole, John F. Zimmerman, Kevin L. Shores, Jennifer H. R. Kenty
Publikováno v:
Lab Chip
Pancreatic β cell function is compromised in diabetes and is typically assessed by measuring insulin secretion during glucose stimulation. Traditionally, measurement of glucose-stimulated insulin secretion involves manual liquid handling, heterogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2856ca8c11804415eacfa12d9c70a21
https://europepmc.org/articles/PMC6814249/
https://europepmc.org/articles/PMC6814249/
Autor:
Jay D. Huenemann, Rodrigo Ledesma Amaro, Michael J. Smanski, Rashmi Tiwari, Nikita Mukhitov, Shue Wang, Suzie Hsu, Robert C. Moseley, Vishwesh V. Kulkarni
New technologies in DNA synthesis and assembly give genetic engineers complete freedom in genetic design, where virtually any plasmid DNA sequence can be created efficiently and economically. Learning how to design, construct, and test new DNA sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b9b0782a532f4f0405eb7fb45f6ec9
https://doi.org/10.1101/745794
https://doi.org/10.1101/745794
Publikováno v:
Nature chemical biology. 16(2)
Materials can be made multifunctional by embedding them with living cells that perform sensing, synthesis, energy production, and physical movement. A challenge is that the conditions needed for living cells are not conducive to materials processing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::817bbca8f82f7e6c6f7b7cbf36413b8e
https://pubmed.ncbi.nlm.nih.gov/31974525
https://pubmed.ncbi.nlm.nih.gov/31974525
Publikováno v:
bioRxiv
Materials can be made multifunctional by embedding them with living cells that perform sensing, synthesis, energy production, and physical movement. A challenge is that the conditions needed for living cells are not conducive to materials processing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1039a24ee64aca45051cf76ea604bb60
https://hdl.handle.net/1721.1/125336
https://hdl.handle.net/1721.1/125336