Výsledky vyhledávání - "Nikita Malev"

Akademický článek

Pleiotropic Effects of the P5-Type ATPase SpfA on Stress Response Networks Contribute to Virulence in the Pathogenic Mold Aspergillus fumigatus

Autor: José P. Guirao-Abad, Martin Weichert, Ginés Luengo-Gil, Sarah Sze Wah Wong, Vishukumar Aimanianda, Christina Grisham, Nikita Malev, Shivani Reddy, Laura Woollett, David S. Askew

Publikováno v: mBio, Vol 12, Iss 5 (2021)

The fungal UPR is an adaptive signaling pathway in the ER that buffers fluctuations in ER stress but also serves as a virulence regulatory hub in species of pathogenic fungi that rely on secretory pathway homeostasis for pathogenicity. This study dem

Externí odkaz: https://doaj.org/article/fa945191fa4942a0a1c0c0808abce8b6

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Pleiotropic Effects of the P5-Type ATPase SpfA on Stress Response Networks Contribute to Virulence in the Pathogenic Mold Aspergillus fumigatus

Autor: Ginés Luengo-Gil, Shivani Reddy, David S. Askew, Laura A. Woollett, Vishukumar Aimanianda, Sarah Sze Wah Wong, José P. Guirao-Abad, Nikita Malev, Christina Grisham, Martin Weichert

Publikováno v: mBio, Vol 12, Iss 5 (2021)
mBio
mBio, 2021, 12 (5), pp.e0273521. ⟨10.1128/mBio.02735-21⟩

International audience; Aspergillus fumigatus is a human-pathogenic mold that extracts nutrients from the environment or from host tissues by secreting hydrolytic enzymes. The ability of A. fumigatus to adjust secretion levels in proportion to demand

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed3ed62f3472da3d765c7c07f883d03e
https://journals.asm.org/doi/10.1128/mBio.02735-21

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