Zobrazeno 1 - 10 of 76 pro vyhledávání: '"Nikita Kotlov"'
1
Akademický článek
Procrustes is a machine-learning approach that removes cross-platform batch effects from clinical RNA sequencing data
Autor: Nikita Kotlov, Kirill Shaposhnikov, Cagdas Tazearslan, Madison Chasse, Artur Baisangurov, Svetlana Podsvirova, Dawn Fernandez, Mary Abdou, Leznath Kaneunyenye, Kelley Morgan, Ilya Cheremushkin, Pavel Zemskiy, Maxim Chelushkin, Maria Sorokina, Ekaterina Belova, Svetlana Khorkova, Yaroslav Lozinsky, Katerina Nuzhdina, Elena Vasileva, Dmitry Kravchenko, Kushal Suryamohan, Krystle Nomie, John Curran, Nathan Fowler, Alexander Bagaev
Publikováno v: Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract With the increased use of gene expression profiling for personalized oncology, optimized RNA sequencing (RNA-seq) protocols and algorithms are necessary to provide comparable expression measurements between exome capture (EC)-based and poly-
Externí odkaz: https://doaj.org/article/1cf786b5cf964d7491ad4bc80679a979
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3
Akademický článek
Deciphering the origin and therapeutic targets of cancer of unknown primary: a case report that illustrates the power of integrative whole-exome and transcriptome sequencing analysis
Autor: Majd Al Assaad, Nara Shin, Michael Sigouros, Jyothi Manohar, Zoia Antysheva, Nikita Kotlov, Daria Kiriy, Anastasiia Nikitina, Mikhail Kleimenov, Anastasiya Tsareva, Anastasiya Makarova, Victoria Fomchenkova, Julia Dubinina, Alexandra Boyko, Nava Almog, David Wilkes, Joanna G. Escalon, Ashish Saxena, Olivier Elemento, Cora N. Sternberg, David M. Nanus, Juan Miguel Mosquera
Publikováno v: Frontiers in Oncology, Vol 13 (2024)
Cancer of unknown primary (CUP) represents a significant diagnostic and therapeutic challenge, being the third to fourth leading cause of cancer death, despite advances in diagnostic tools. This article presents a successful approach using a novel ge
Externí odkaz: https://doaj.org/article/13acdf4ab307414bb760f79ae7f83824
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9
Akademický článek
B-Cell Infiltrate in the Tumor Microenvironment Is Associated With Improved Survival in Resected Lung Adenocarcinoma
Autor: Ibiayi Dagogo-Jack, MD, Ivan Valiev, MD, Nikita Kotlov, MS, Anna Belozerova, MD, Aleksandra Lopareva, MS, MD, Anna Butusova, MS, Naira Samarina, PhD, Alexandra Boyko, MS, Zhongmin Xiang, PhD, Monique Johnson, BS, Sandrine Degryse, PhD, Florence K. Keane, MD, Lecia V. Sequist, MD, Michael Lanuti, MD, Nathan Fowler, MD, Mari Mino-Kenudson, MD, Alexander Bagaev, PhD
Publikováno v: JTO Clinical and Research Reports, Vol 4, Iss 7, Pp 100527- (2023)
Introduction: Relapse is common after resection of lung adenocarcinoma (LUAD). Features of the tumor microenvironment (TME) which influence postsurgical survival outcomes are poorly characterized. Here, we analyzed the TME of more than 1500 LUAD spec
Externí odkaz: https://doaj.org/article/acbc54d5c39b41eeb5768d2ee56dbc4c
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10
Akademický článek
Doublecortin-Like Kinase 1 (DCLK1) Is a Novel NOTCH Pathway Signaling Regulator in Head and Neck Squamous Cell Carcinoma
Autor: Esther C. Broner, Jonathan A. Trujillo, Michael Korzinkin, Tejaswini Subbannayya, Nishant Agrawal, Ivan V. Ozerov, Alex Zhavoronkov, Lisa Rooper, Nikita Kotlov, Le Shen, Alexander T. Pearson, Ari J. Rosenberg, Peter A. Savage, Vasudha Mishra, Aditi Chatterjee, David Sidransky, Evgeny Izumchenko
Publikováno v: Frontiers in Oncology, Vol 11 (2021)
Despite recent advancements, the 5 year survival of head and neck squamous cell carcinoma (HNSCC) hovers at 60%. DCLK1 has been shown to regulate epithelial-to-mesenchymal transition as well as serving as a cancer stem cell marker in colon, pancreati
Externí odkaz: https://doaj.org/article/2050f94809f344348709fe437dccb6db
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