Complex trait susceptibilities and population diversity in a sample of 4,145 Russians

Autor: Dmitrii Usoltsev, Nikita Kolosov, Oxana Rotar, Alexander Loboda, Maria Boyarinova, Ekaterina Moguchaya, Ekaterina Kolesova, Anastasia Erina, Kristina Tolkunova, Valeriia Rezapova, Ivan Molotkov, Olesya Melnik, Olga Freylikhman, Nadezhda Paskar, Asiiat Alieva, Elena Baranova, Elena Bazhenova, Olga Beliaeva, Elena Vasilyeva, Sofia Kibkalo, Rostislav Skitchenko, Alina Babenko, Alexey Sergushichev, Alena Dushina, Ekaterina Lopina, Irina Basyrova, Roman Libis, Dmitrii Duplyakov, Natalya Cherepanova, Kati Donner, Paivi Laiho, Anna Kostareva, Alexandra Konradi, Evgeny Shlyakhto, Aarno Palotie, Mark J. Daly, Mykyta Artomov

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)

Abstract The population of Russia consists of more than 150 local ethnicities. The ethnic diversity and geographic origins, which extend from eastern Europe to Asia, make the population uniquely positioned to investigate the shared properties of inhe

Externí odkaz: https://doaj.org/article/5db0f79709df484e81724be4b4650737

Case Report: Supernormal Vascular Aging in Leningrad Siege Survivors

Autor: Oxana Rotar, Maria Boyarinova, Ekaterina Moguchaya, Kristina Tolkunova, Nikita Kolosov, Valeriia Rezapova, Olga Freylikhman, Dmitrii Usoltsev, Olesya Melnik, Alexey Sergushichev, Vladislav Solntsev, Anna Kostareva, Elena Dubinina, Trudy Voortman, Christine Stevens, Mark J. Daly, Alexandra Konradi, Evgeny Shlyakhto, Mykyta Artomov

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 9 (2022)

Age-related changes in the vascular system play an important role in the biological age and lifespan of a person and maybe affected from an early age onward. One of the indicators of changes in the vascular system is arterial wall stiffness and its m

Externí odkaz: https://doaj.org/article/8592d23bf3ef48c5bd11bfbd3e33ad47

Retroelement-Linked H3K4me1 Histone Tags Uncover Regulatory Evolution Trends of Gene Enhancers and Feature Quickly Evolving Molecular Processes in Human Physiology

Autor: Daniil Nikitin, Nikita Kolosov, Anastasiia Murzina, Karina Pats, Anton Zamyatin, Victor Tkachev, Maxim Sorokin, Philippe Kopylov, Anton Buzdin

Publikováno v: Cells, Vol 8, Iss 10, p 1219 (2019)

Background: Retroelements (REs) are mobile genetic elements comprising ~40% of human DNA. They can reshape expression patterns of nearby genes by providing various regulatory sequences. The proportion of regulatory sequences held by REs can serve a m

Externí odkaz: https://doaj.org/article/0dd8681ce72e4f1fbf0ea6e2eda00928

РАСШИРЕНИЕ ДИАПАЗОНА ОПРЕДЕЛЕНИЯ ЭЛЕМЕНТОВ НА АТОМНО-АБСОРБЦИОННОМ СПЕКТРОМЕТРЕ «ГРАНД-ААС» С ИСПОЛЬЗОВАНИЕМ НЕСКОЛЬКИХ ИХ ЛИНИЙ ПОГЛОЩЕНИЯ

Autor: Vladimir Labusov, Nikita Kolosov, Svetlana Boldova

Publikováno v: Analitika i kontrol` (Analytics and control); Том 25, № 4 (2021): «ВМК-Оптоэлектроника»; P. 318-325
Аналитика и контроль; Том 25, № 4 (2021): «ВМК-Оптоэлектроника»; P. 318-325

One limitation of atomic absorption spectrometry is the narrow range of measurable concentration (1–2 orders of magnitude). In simultaneous multi-element analysis, this may require multiple dilutions of the sample to determine several elements with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a67c6c4138c61bb69b645e73e9fd4f
https://journals.urfu.ru/index.php/analitika/article/view/5556

Prioritization of disease genes from GWAS using ensemble-based positive-unlabeled learning

Autor: Mykyta Artomov, Mark J. Daly, Nikita Kolosov

Publikováno v: Eur J Hum Genet

A primary challenge in understanding disease biology from genome-wide association studies (GWAS) arises from the inability to directly implicate causal genes from association data. Integration of multiple-omics data sources potentially provides impor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90049a76fea6e280d27132158a63b9b6
https://europepmc.org/articles/PMC8484264/