Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nikita Ikon"'
Autor:
Rena A. Mizrahi, Wendy Y. Lin, Ashley Gras, Ariel R. Niedecken, Ellen K. Wagner, Sheila M. Keating, Nikita Ikon, Vishal A. Manickam, Michael A. Asensio, Jackson Leong, Angelica V. Medina-Cucurella, Emily Benzie, Kyle P. Carter, Yao Chiang, Robert C. Edgar, Renee Leong, Yoong Wearn Lim, Jan Fredrik Simons, Matthew J. Spindler, Kacy Stadtmiller, Nicholas Wayham, Dirk Büscher, Jose Vicente Terencio, Clara Di Germanio, Steven M. Chamow, Charles Olson, Paula A. Pino, Jun-Gyu Park, Amberlee Hicks, Chengjin Ye, Andreu Garcia-Vilanova, Luis Martinez-Sobrido, Jordi B. Torrelles, David S. Johnson, Adam S. Adler
Publikováno v:
Pathogens, Vol 11, Iss 7, p 806 (2022)
Conventionally, hyperimmune globulin drugs manufactured from pooled immunoglobulins from vaccinated or convalescent donors have been used in treating infections where no treatment is available. This is especially important where multi-epitope neutral
Externí odkaz:
https://doaj.org/article/30fbcf61da8b46ddab93ba7e247ee57f
Publikováno v:
Biochim Biophys Acta Biomembr
Miniature membranes comprised of tetramyristoylcardiolipin (CL) and apolipoprotein (apo) A-I, termed nanodisks (ND), are stable, aqueous soluble, reconstituted high density lipoproteins. When CL ND, but not dimyristoylphosphatidylcholine (PC) ND, wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af670fe077dc3f67b8417fd3b323cb8d
https://doi.org/10.1016/j.bbamem.2019.03.005
https://doi.org/10.1016/j.bbamem.2019.03.005
Publikováno v:
Biochemical and Biophysical Research Communications. 464:580-585
The concentration and composition of cardiolipin (CL) in mitochondria are altered in age-related heart disease, Barth Syndrome, and other rare genetic disorders, resulting in mitochondrial dysfunction. To explore whether exogenous CL can be delivered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd0867b9c6df69ab13181c8a9f1c926
https://doi.org/10.1016/j.bbrc.2015.07.012
https://doi.org/10.1016/j.bbrc.2015.07.012
Autor:
Ayako Kamei, Jesse J. Tran, Robert O. Ryan, Robert S. Kiss, Jennifer A. Beckstead, Gang Ren, Paul M.M. Weers, Jennifer Shearer, Jianfang Liu, Nikita Ikon, ShiBo Feng
Publikováno v:
Ikon, N; Shearer, J; Liu, J; Tran, JJ; Feng, SB; Kamei, A; et al.(2017). A facile method for isolation of recombinant human apolipoprotein A-I from E. coli. Protein Expression and Purification, 134, 18-24. doi: 10.1016/j.pep.2017.03.015. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/1g08b4st
© 2017 Elsevier Inc. Apolipoprotein (apo) A-I is the major protein component of high-density lipoprotein (HDL) and plays key roles in the Reverse Cholesterol Transport pathway. In the past decade, reconstituted HDL (rHDL) has been employed as a ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b31dc34f2293c58be1a6bd1df73306c
https://escholarship.org/uc/item/1g08b4st
https://escholarship.org/uc/item/1g08b4st
Autor:
Robert O. Ryan, Nikita Ikon
A fundamental question in cell biology, under investigation for over six decades, is the structural organization of mitochondrial cristae. Long known to harbor electron transport chain proteins, crista membrane integrity is key to establishment of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f73944bd91256ea0bf94676e62775d1
https://europepmc.org/articles/PMC5426559/
https://europepmc.org/articles/PMC5426559/
Autor:
Nikita Ikon, Robert O. Ryan
The Barth syndrome (BTHS) is caused by an inborn error of metabolism that manifests characteristic phenotypic features including altered mitochondrial membrane phospholipids, lactic acidosis, organic acid-uria, skeletal muscle weakness and cardiomyop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8efdd9a7d5e345a0356e59c56add57
https://europepmc.org/articles/PMC5288132/
https://europepmc.org/articles/PMC5288132/
Publikováno v:
Journal of Biomedical Research
Barth syndrome (BTHS) is a mitochondrial disorder characterized by cardiomyopathy and skeletal muscle weakness. Disease results from mutations in the tafazzin (TAZ) gene, encoding a phospholipid transacylase. Defective tafazzin activity results in an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::011948ca9616dcced9d203e5997c79d3
https://doi.org/10.7555/jbr.32.20170094
https://doi.org/10.7555/jbr.32.20170094
Publikováno v:
ResearcherID
The mammalian target of rapamycin (mTOR) kinase is a master regulator of cellular, developmental, and metabolic processes. Deregulation of mTOR signaling is implicated in numerous human diseases including cancer and diabetes. mTOR functions as part o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dfb1a7e069f8bb6e3c72e683b3ce833
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=CCC&KeyUT=CCC:000346366500053&KeyUID=CCC:000346366500053
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=CCC&KeyUT=CCC:000346366500053&KeyUID=CCC:000346366500053