Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Nikita A. Sakhanenko"'
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background Permutation testing is often considered the “gold standard” for multi-test significance analysis, as it is an exact test requiring few assumptions about the distribution being computed. However, it can be computationally very
Externí odkaz:
https://doaj.org/article/3a77b291e81c46bcac08e9557dd8db84
Autor:
Theresa A. Lusardi, Ursula S. Sandau, Nikita A. Sakhanenko, Sarah Catherine B. Baker, Jack T. Wiedrick, Jodi A. Lapidus, Murray A. Raskind, Ge Li, Elaine R. Peskind, David J. Galas, Joseph F. Quinn, Julie A. Saugstad
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
A history of traumatic brain injury (TBI) increases the odds of developing Alzheimer’s disease (AD). The long latent period between injury and dementia makes it difficult to study molecular changes initiated by TBI that may increase the risk of dev
Externí odkaz:
https://doaj.org/article/04934a033db94acca68861ee751f4e26
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 7, Pp 2071-2088 (2019)
We describe an information-theory-based method and associated software for computationally identifying sister spores derived from the same meiotic tetrad. The method exploits specific DNA sequence features of tetrads that result from meiotic centrome
Externí odkaz:
https://doaj.org/article/d7624589b0994064baef2e63b4daddf3
Autor:
David J. Galas, Nikita A. Sakhanenko
Publikováno v:
Entropy, Vol 21, Iss 1, p 88 (2019)
Relations between common information measures include the duality relations based on Möbius inversion on lattices, which are the direct consequence of the symmetries of the lattices of the sets of variables (subsets ordered by inclusion). In this pa
Externí odkaz:
https://doaj.org/article/6176b8efb1304e6ba68c58c77fa976ab
Publikováno v:
Axioms, Vol 6, Iss 2, p 8 (2017)
Inferring and comparing complex, multivariable probability density functions is fundamental to problems in several fields, including probabilistic learning, network theory, and data analysis. Classification and prediction are the two faces of this cl
Externí odkaz:
https://doaj.org/article/53cff497cc5440bc868ff5c7e120f21d
Publikováno v:
Entropy, Vol 19, Iss 3, p 104 (2017)
We apply a network complexity measure to the gap junction network of the somatic nervous system of C. elegans and find that it possesses a much higher complexity than we might expect from its degree distribution alone. This “excess” complexity is
Externí odkaz:
https://doaj.org/article/45c52acc149f4fd49a51b2a8bcd6bf3e
Publikováno v:
Journal of Computational Biology. 30:323-336
Publikováno v:
Journal of Computational Biology
Quantitative genetics has evolved dramatically in the past century, and the proliferation of genetic data, in quantity as well as type, enables the characterization of complex interactions and mechanisms beyond the scope of its theoretical foundation
Publikováno v:
Journal of Computational Biology
Missing values in complex biological data sets have significant impacts on our ability to correctly detect and quantify interactions in biological systems and to infer relationships accurately. In this article, we propose a useful metaphor to show th
Publikováno v:
Proceedings of Entropy 2021: The Scientific Tool of the 21st Century.
Developing an information theory of quantitative genetics David J. Galas, James Kunert-Graf and Nikita A. Sakhanenko Pacific Northwest Research Institute, Seattle Washington, 98122 USA Quantitative genetics has evolved dramatically in the century sin