Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Niki Zacharias Millward"'
Autor:
José S Enriquez, Yan Chu, Shivanand Pudakalakatti, Kang Lin Hsieh, Duncan Salmon, Prasanta Dutta, Niki Zacharias Millward, Eugene Lurie, Steven Millward, Florencia McAllister, Anirban Maitra, Subrata Sen, Ann Killary, Jian Zhang, Xiaoqian Jiang, Pratip K Bhattacharya, Shayan Shams
Publikováno v:
JMIR Medical Informatics, Vol 9, Iss 6, p e26601 (2021)
BackgroundThere is an unmet need for noninvasive imaging markers that can help identify the aggressive subtype(s) of pancreatic ductal adenocarcinoma (PDAC) at diagnosis and at an earlier time point, and evaluate the efficacy of therapy prior to tumo
Externí odkaz:
https://doaj.org/article/d4b6c6b5358444b8ab23efe0bed8fa1d
Autor:
Marina Konopleva, Michael Andreeff, Charles P. Hart, Jorge E. Cortes, James A. Bankson, R. Eric Davis, Joseph R. Marszalek, Pratip K. Bhattacharya, Jaehyuk Lee, Hong Mu, Marina Protopopova, Andrei Volgin, Teresa McQueen, Sergej Konoplev, Helen Ma, Rodrigo Jacamo, Polina Matre, Yue-xi Shi, Hongbo Lu, Karine G. Harutyunyan, Juliana Velez, Niki Zacharias Millward, Marc S. Ramirez, Juliana Benito
Supplementary Figure S1. TH-302 has potent antitumor activity in a 3D in vitro co-culture system of leukemia cells and bone marrow-derived mesenchymal stromal cells that recapitulates the multidimensional BM niche Supplementary Figure S2. Hypoxia is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef732231bc5c4b2a83cc69ca5faf76c
https://doi.org/10.1158/1078-0432.22458932.v1
https://doi.org/10.1158/1078-0432.22458932.v1
Autor:
Marina Konopleva, Michael Andreeff, Charles P. Hart, Jorge E. Cortes, James A. Bankson, R. Eric Davis, Joseph R. Marszalek, Pratip K. Bhattacharya, Jaehyuk Lee, Hong Mu, Marina Protopopova, Andrei Volgin, Teresa McQueen, Sergej Konoplev, Helen Ma, Rodrigo Jacamo, Polina Matre, Yue-xi Shi, Hongbo Lu, Karine G. Harutyunyan, Juliana Velez, Niki Zacharias Millward, Marc S. Ramirez, Juliana Benito
Supplemental Methods and Tables 1) mRNA Hybridization and Gene-expression Profiling. 2) Gene expression analysis by Nanostring technology. 3) Hyperpolarized Magnetic Resonance Spectroscopy. 4) In Vitro 1-13C Pyruvic Acid Feeding Studies and High Reso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6101dc27a129145a1fdb44ed9240c4e4
https://doi.org/10.1158/1078-0432.22458929
https://doi.org/10.1158/1078-0432.22458929
Autor:
Marina Konopleva, Michael Andreeff, Charles P. Hart, Jorge E. Cortes, James A. Bankson, R. Eric Davis, Joseph R. Marszalek, Pratip K. Bhattacharya, Jaehyuk Lee, Hong Mu, Marina Protopopova, Andrei Volgin, Teresa McQueen, Sergej Konoplev, Helen Ma, Rodrigo Jacamo, Polina Matre, Yue-xi Shi, Hongbo Lu, Karine G. Harutyunyan, Juliana Velez, Niki Zacharias Millward, Marc S. Ramirez, Juliana Benito
Purpose: To characterize the prevalence of hypoxia in the leukemic bone marrow, its association with metabolic and transcriptional changes in the leukemic blasts and the utility of hypoxia-activated prodrug TH-302 in leukemia models.Experimental Desi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fc092694b38524573ab9a62029cade
https://doi.org/10.1158/1078-0432.c.6524084
https://doi.org/10.1158/1078-0432.c.6524084
Autor:
Steven W. Millward, Shivanand Pudakalakatti, Anirban Maitra, Xiaoqian Jiang, Jian Zhang, Niki Zacharias Millward, Prasanta Dutta, Subrata Sen, Kang Lin Hsieh, Ann M. Killary, Yan Chu, Duncan Salmon, Eugene Lurie, Florencia McAllister, Pratip K. Bhattacharya, Shayan Shams, José S. Enriquez
Publikováno v:
JMIR Medical Informatics, Vol 9, Iss 6, p e26601 (2021)
JMIR Medical Informatics
JMIR Medical Informatics
Background There is an unmet need for noninvasive imaging markers that can help identify the aggressive subtype(s) of pancreatic ductal adenocarcinoma (PDAC) at diagnosis and at an earlier time point, and evaluate the efficacy of therapy prior to tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe624a1a31b64401d7b6b043cc54b9d
https://medinform.jmir.org/2021/6/e26601
https://medinform.jmir.org/2021/6/e26601
Autor:
José S Enriquez, Yan Chu, Shivanand Pudakalakatti, Kang Lin Hsieh, Duncan Salmon, Prasanta Dutta, Niki Zacharias Millward, Eugene Lurie, Steven Millward, Florencia McAllister, Anirban Maitra, Subrata Sen, Ann Killary, Jian Zhang, Xiaoqian Jiang, Pratip K Bhattacharya, Shayan Shams
BACKGROUND There is an unmet need for noninvasive imaging markers that can help identify the aggressive subtype(s) of pancreatic ductal adenocarcinoma (PDAC) at diagnosis and at an earlier time point, and evaluate the efficacy of therapy prior to tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2c647c70f194ee1ffc252df6f60b82a
https://doi.org/10.2196/preprints.26601
https://doi.org/10.2196/preprints.26601
Autor:
Matthew T. Campbell, Surena F. Matin, Alexandria Childs, Daniel D. Shapiro, Kanishka Sircar, Mary E. Westerman, Alberto C. Pieretti, Priya Rao, Eric Jonasch, Jose A. Karam, Christopher G. Wood, Nizar M. Tannir, Niki Zacharias Millward
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 39:790.e17-790.e23
The presence of sarcomatoid features and/or lymph node-positive disease may be associated with a worse prognosis in chromophobe renal cell carcinoma (ChRCC). We sought to better characterize patients' long-term outcomes with these features compared w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6930119dbd8f4ae22653ba493444a7f0
https://doi.org/10.1016/j.urolonc.2021.06.016
https://doi.org/10.1016/j.urolonc.2021.06.016
Autor:
Jingzhe Hu, Jaehyuk Lee, Joseph Weygand, Travis C. Salzillo, Niki Zacharias Millward, Shivanand Pudakalakatti, Linda Nguyen, Prasanta Dutta, Amy B. Heimberger, Nicholas Whiting, Frederick F. Lang, Pratip K. Bhattacharya, Seth T. Gammon
Publikováno v:
Magnetic Resonance Imaging Clinics of North America. 24:687-703
This article reviews existing and emerging techniques of interrogating metabolism in brain cancer from well-established proton magnetic resonance spectroscopy to the promising hyperpolarized metabolic imaging and chemical exchange saturation transfer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234ef5595caae4368567ef9c06475ba6
https://doi.org/10.1016/j.mric.2016.07.003
https://doi.org/10.1016/j.mric.2016.07.003
Autor:
Young Bok Lee, Niki Zacharias Millward, Hyeonglim Seo, Gijin Jeong, Ikjang Choi, Hyeji Ko, Pratip K. Bhattacharya, Jee Wook Lee, Gyeonghyeon Gong
Publikováno v:
Journal of Industrial and Engineering Chemistry. 36:224-228
We utilized dynamic nuclear polarization to hyperpolarize three metabolic imaging agents as single agents and together (co-polarization with two different organic radicals; OX63 and BDPA). In addition, we describe our initial two slice selective spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::149bd812f284f727995244b5492f52b5
https://doi.org/10.1016/j.jiec.2016.02.002
https://doi.org/10.1016/j.jiec.2016.02.002
Autor:
Nouara C. Sadaoui, Gabriel Lopez-Berestein, Jaehyuk Lee, Jennifer B. Dennison, Cristina Ivan, Rebecca A. Previs, Manuela Ferracin, Cristian Rodriguez-Aguayo, Monika Haemmerle, Pratip K. Bhattacharya, Kshipra M. Gharpure, Anil K. Sood, Rajesha Rupaimoole, Jeffery Kovacs, Sunila Pradeep, Wei Zhang, Sherry Y. Wu, Nidhin Sam, Michael McGuire, Ronny Drapkin, Hui Ling, Niki Zacharias Millward, Archana S. Nagaraja, Gordon B. Mills, Guillermo N. Armaiz-Pena, George A. Calin
Publikováno v:
Cell Reports, Vol 13, Iss 11, Pp 2395-2402 (2015)
SummaryLong noncoding RNAs (lncRNAs) significantly influence the development and regulation of genome expression in cells. Here, we demonstrate the role of lncRNA ceruloplasmin (NRCP) in cancer metabolism and elucidate functional effects leading to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8264f587f0b8ad45be7c267f9967da41