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of 5
pro vyhledávání: '"Niki Fortune"'
Autor:
Anna Hemnes, Niki Fortune, Katie Simon, Irina A. Trenary, Sheila Shay, Eric Austin, Jamey D. Young, Evan Britain, James West, Megha Talati
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundIn PAH metabolic abnormalities in multiple pathways are well-recognized features of right ventricular dysfunction, however, prior work has focused mainly on the use of a single “omic” modality to describe a single deranged pathway. We i
Externí odkaz:
https://doaj.org/article/22d6d48498684b8396f4cc91e68694e9
Autor:
Megha Talati, Evan Brittain, Vineet Agrawal, Niki Fortune, Katie Simon, Sheila Shay, Xiaofang Zeng, Michael L. Freeman, James West, Anna Hemnes
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionPulmonary arterial hypertension is a fatal cardiopulmonary disease. Leptin, a neuroendocrine hormone released by adipose tissue, has a complex relationship with cardiovascular diseases, including PAH. Leptin is thought to be an important
Externí odkaz:
https://doaj.org/article/18126b69c87e4ec29b237f8c7e6df4a2
Autor:
Vineet Agrawal, Anna R. Hemnes, Nicholas J. Shelburne, Niki Fortune, Julio L. Fuentes, Dan Colvin, Marion W. Calcutt, Megha Talati, Emily Poovey, James D. West, Evan L. Brittain
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 3, Pp n/a-n/a (2022)
Abstract Pulmonary arterial hypertension (PAH) is a fatal vasculopathy that ultimately leads to elevated pulmonary pressure and death by right ventricular (RV) failure, which occurs in part due to decreased fatty acid oxidation and cytotoxic lipid ac
Externí odkaz:
https://doaj.org/article/5f982da54b464a12a0b70bc83b5a374f
Autor:
Vineet Agrawal, Niki Fortune, Sheeline Yu, Julio Fuentes, Fubiao Shi, David Nichols, Linda Gleaves, Emily Poovey, Thomas J. Wang, Evan L. Brittain, Sheila Collins, James D. West, Anna R. Hemnes
Publikováno v:
Pulmonary Circulation, Vol 9 (2019)
Heart failure with preserved ejection fraction (HFpEF) currently has no therapies that improve mortality. Right ventricular dysfunction and pulmonary hypertension are common in HFpEF, and thought to be driven by obesity and metabolic syndrome. Thus,
Externí odkaz:
https://doaj.org/article/5d105d71b22f48f3af7f3fc4cde41f3d
Autor:
Evan L. Brittain, Megha Talati, Niki Fortune, Vineet Agrawal, David F. Meoli, James West, Anna R. Hemnes
Publikováno v:
Pulmonary Circulation, Vol 9 (2018)
Little is known about the impact of metabolic syndrome (MS) on right ventricular (RV) structure and function. We hypothesized that mice fed a Western diet (WD) would develop RV lipid accumulation and impaired RV function, which would be ameliorated w
Externí odkaz:
https://doaj.org/article/c7ad4f5fd05b48039ada68cc7678f67d