Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Niki C Carty"'
Autor:
Pradeep Kurup, Stephanie M. Fernandez, Niki C. Carty, Constantinos D. Paspalas, Susan M. Goebel-Goody, Matthew L. Baum, Paul J. Lombroso
Publikováno v:
Pharmacological Reviews. 64:65-87
Striatal-enriched protein tyrosine phosphatase (STEP) is a brain-specific phosphatase that modulates key signaling molecules involved in synaptic plasticity and neuronal function. Targets include extracellular-regulated kinase 1 and 2 (ERK1/2), stres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2fc3bc2b642caa2cc47f336b04a12d
https://doi.org/10.1124/pr.110.003053
https://doi.org/10.1124/pr.110.003053
Autor:
Marcia N. Gordon, Paul E. Gottschall, Dave Morgan, Niki C Carty, Nicholas Muzyczka, Mary Mercer, Craig Meyers, Daniel C. Lee, Kevin Nash
Publikováno v:
Molecular Therapy. 16:1580-1586
Reduction of Aβ deposition is a major therapeutic strategy in Alzheimer's disease (AD). The concentration of Aβ in the brain is modulated not only by Aβ production but also by its degradation. One of the proteases involved in the degradation of A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae22b7f2392391714cf275a7f46ed0c
https://doi.org/10.1038/mt.2008.148
https://doi.org/10.1038/mt.2008.148
Autor:
Dave Morgan, Milene Brownlow, Niki C Carty, Marcia N. Gordon, Maj-Linda B. Selenica, Dana Cruite, Kevin Nash
Publikováno v:
Alzheimer's & Dementia. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a47eb03baee9c9af514569ca13dffc6
https://doi.org/10.1016/j.jalz.2010.05.1806
https://doi.org/10.1016/j.jalz.2010.05.1806
Publikováno v:
Alzheimer's & Dementia. 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::510150951bd8438b73f75645726911f1
https://doi.org/10.1016/j.jalz.2008.05.1504
https://doi.org/10.1016/j.jalz.2008.05.1504
Autor:
Niki C Carty, Arnon Rosenthal, Dave Morgan, Jaume Pons, Donna M. Wilcock, Paul E. Gottschall, Marcia N. Gordon, Jan Grimm, Victoria Ronan
Publikováno v:
Journal of Neuroinflammation, Vol 3, Iss 1, p 11 (2006)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Antibodies against the Aß peptide clear Aß deposits when injected intracranially. Deglycosylated antibodies have reduced effector functions compared to their intact counterparts, potentially avoiding immune activation. Methods Deglycosyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3499ff2dd19f2c225fa5e620218b2c2c
https://doi.org/10.1186/1742-2094-3-11
https://doi.org/10.1186/1742-2094-3-11