Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Nikhilesh N. Singh"'
Publikováno v:
Gastroenterology. 158:S-853
Autor:
Nikhilesh N. Singh, Thomas Roth, Frank Steinberg, David J. Greenblatt, Jerold S. Harmatz, Ram P. Kapil, Stephen C. Harris
Publikováno v:
Drugs & Aging. 31:731-736
Pharmacokinetic parameters of sedative–hypnotic medications can be influenced by age and gender. This study analyzed pharmacokinetic parameters of zolpidem, formulated as a sublingual zolpidem tartrate tablet (ZST; Intermezzo®), in healthy elderly
Autor:
Nikhilesh N. Singh, David J. Greenblatt, Frank Steinberg, M. Moline, Stephen C. Harris, Ram P. Kapil, Jerold S. Harmatz, Thomas Roth
Publikováno v:
The Journal of Clinical Pharmacology. 54:282-290
The effect of dose and gender on the pharmacokinetics (PK) and pharmacodynamics (PD) of zolpidem after administration of a buffered zolpidem sublingual tablet (ZST; Intermezzo®, Purdue Pharma L.P., Stamford, CT, USA) was evaluated in healthy non-eld
Publikováno v:
Human Psychopharmacology: Clinical and Experimental. 29:25-30
Objective Evaluate potential gender effects on efficacy and safety of a buffered zolpidem sublingual tablet (ZST) formulation. Methods Post hoc analysis of the pivotal sleep laboratory and outpatient studies, per gender. Results In the sleep laborato
Publikováno v:
Human Psychopharmacology
Objectives Buffered low-dose sublingual transmucosal zolpidem lozenge hemitartrate (ST zolpidem) is being developed for the treatment of middle-of-the-night insomnia. The objective of this double-blind placebo-controlled cross-over study (n = 24) was
Autor:
David J, Greenblatt, Jerold S, Harmatz, Nikhilesh N, Singh, Frank, Steinberg, Thomas, Roth, Margaret L, Moline, Stephen C, Harris, Ram P, Kapil
Publikováno v:
Journal of clinical pharmacology. 54(3)
The effect of dose and gender on the pharmacokinetics (PK) and pharmacodynamics (PD) of zolpidem after administration of a buffered zolpidem sublingual tablet (ZST; Intermezzo®, Purdue Pharma L.P., Stamford, CT, USA) was evaluated in healthy non-eld
Autor:
David J. Greenblatt, Ram P. Kapil, Jerold S. Harmatz, Thomas Roth, Nikhilesh N. Singh, Stephen C. Harris
Publikováno v:
The Journal of Clinical Pharmacology.
Ingesting food can impact the pharmacokinetics of sedative-hypnotic drugs. A buffered zolpidem sublingual tablet (ZST) recently became available for the treatment of middle-of-the-night awakening. In this randomized, open-label, single-site study, th
Publikováno v:
Human psychopharmacology. 29(1)
Evaluate potential gender effects on efficacy and safety of a buffered zolpidem sublingual tablet (ZST) formulation.Post hoc analysis of the pivotal sleep laboratory and outpatient studies, per gender.In the sleep laboratory study, polysomnography-de
Publikováno v:
Sleep Medicine. 14:e211-e212
Introduction Aside from inducing and maintaining sleep, hypnotic medications also impact sleep stages. Historically, the barbiturates were REM suppressants, while the benzodiazepines were Stage 3–4 (SWS) suppressants. The newer benzodiazepine recep
Autor:
Alicia C. Shillington, Victoria Shahly, Nikhilesh N. Singh, Ronald C. Kessler, Judith J. Stephenson, Thomas Roth, Patricia A. Berglund, Denise Cooke
Publikováno v:
Sleep Medicine. 12:S6