Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Nikhil Reddy Madadi"'
Autor:
Narsimha Reddy Penthala, Nikhil Reddy Madadi, Shobanbabu Bommagani, Sean Parkin, Peter A. Crooks
Publikováno v:
Acta Crystallographica Section E, Vol 70, Iss 11, Pp 392-395 (2014)
The title compound, C19H17N3O3S (I), was prepared by a [3 + 2]cycloaddition azide condensation reaction using sodium azide and l-proline as a Lewis base catalyst. N-Methylation of compound (I) using CH3I gave compound (II), C20H19N3O3S. The benzothio
Externí odkaz:
https://doaj.org/article/ce281d44e6794c01830abda69376dfc7
Autor:
Nikhil Reddy Madadi, Narsimha Reddy Penthala, Shobanbabu Bommagani, Sean Parkin, Peter A. Crooks
Publikováno v:
Acta Crystallographica Section E, Vol 70, Iss 10, Pp o1128-o1129 (2014)
The title compound, C20H23N3O6·CH3OH, was synthesized by [3 + 2] cycloaddition of (Z)-2,3-bis(3,4,5-trimethoxyphenyl)acrylonitrile with sodium azide and ammonium chloride in DMF/water. The central nitrogen of the triazole ring is protonated. The dih
Externí odkaz:
https://doaj.org/article/f39f8ce9d1fd46b885c73d0a002c719b
Autor:
Venumadhav Janganati, Narsimha Reddy Penthala, Nikhil Reddy Madadi, Sean Parkin, Peter A. Crooks
Publikováno v:
Acta Crystallographica Section E, Vol 70, Iss 3, Pp o372-o373 (2014)
The title monosuccinate derivative of melampomagnolide B [systematic name: 4-(((1aR,7aS,10aS,10bS,E)-1a-methyl-8-methylene-9-oxo-1a,2,3,6,7,7a,8,9,10a,10b-decahydrooxireno[2′,3′:9,10]cyclodeca[1,2-b]furan-5-yl)methoxy)-4-oxobutanoic acid], C19H24
Externí odkaz:
https://doaj.org/article/f1f1a0c3e08943f68d3ce7c613f5b904
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 3, Pp o730-o730 (2012)
The crystal structure of the title compound, C25H27NO4, shows the presence of a double bond with Z geometry which connects the quinuclidin-3-one ring and the trimethoxyresveratrol moiety. The dihedral angle between the two benzene rings in the stilbe
Externí odkaz:
https://doaj.org/article/778ecb47a3074f00b35a2b07484d8289
Autor:
Nikhil Reddy Madadi, Thirupathi Reddy Yerram Reddy, Narsimha Reddy Penthala, Sean Parkin, Peter A. Crooks
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 7, Pp o1792-o1792 (2010)
In the crystal structure of the title compound, C21H20N2O4S·CH3OH, molecules are linked into chains by a series of intermolecular N—H...O, N—H...N and O—H...O hydrogen bonds. The molecular structure shows a double bond with Z geometry, connect
Externí odkaz:
https://doaj.org/article/d7eab6b373bd4b6195c016ccf30996a0
Autor:
Narsimha Reddy Penthala, Venumadhav Janganati, Hongliang Zong, Robert L. Eoff, Peter A. Crooks, Amit Ketkar, Nikhil Reddy Madadi, Monica L. Guzman
Publikováno v:
European Journal of Medicinal Chemistry. 92:212-220
A series of heterocyclic combretastatin analogues have been synthesized and evaluated for their anticancer activity against a panel of 60 human cancer cell lines. The most potent compounds were two 3,4,5-trimethoxy phenyl analogues containing either
Autor:
Robert L. Eoff, Shraddha Thakkar, Leena Madhukuri, Gauri Lamture, Narsimha Reddy Penthala, Nikhil Reddy Madadi, Peter A. Crooks
Publikováno v:
MedChemComm. 6:1535-1543
trans-Cyanocombretastatin A-4 (trans-CA-4) analogues have been structurally modified to afford their more stable CA-4-(2H)-1,2,3-triazole analogues. Fifteen novel, stable 4-heteroaryl-5-aryl-(2H)-1,2,3-triazole CA-4 analogues (8a-i, 9 and 11a-e) were
Autor:
Robert L. Eoff, Shobanbabu Bommagani, Hongliang Zong, Amit Ketkar, Chen Zheng, Narsimha Reddy Penthala, Nikhil Reddy Madadi, Peter A. Crooks, Venumadhav Janganati, Monica L. Guzman
Publikováno v:
MedChemComm. 6:788-794
A series of novel diarylacrylonitrile and trans-stilbene analogues of resveratrol has been synthesized and evaluated for their anticancer activities against a panel of 60 human cancer cell lines. The diarylacrylonitrile analogues 3b and 4a exhibited
Autor:
Narsimha Reddy Penthala, Nikhil Reddy Madadi, Peter A. Crooks, Sean Parkin, Shobanbabu Bommagani
Publikováno v:
Acta Crystallographica Section E: Structure Reports
Acta Crystallographica Section E, Vol 70, Iss 11, Pp 392-395 (2014)
Acta Crystallographica Section E, Vol 70, Iss 11, Pp 392-395 (2014)
In the crystal structure of (I), the molecules are linked into chains by N—H⋯O hydrogen bonds with (5) ring motifs. After the N-methylation of structure (I), no hydrogen-bonding interactions were observed for structure (II).
The title
The title
Publikováno v:
Tetrahedron Letters. 55:5562-5565
Use of a novel reagent has been established for the synthesis of a series of 4,5-diaryl-2H-1,2,3-triazoles (6a-i and 9a-e) from cyanostilbene analogs of benzo[b]thiophene, benzo[b]furan and indole, catalyzed by L-proline via Lewis base-catalyzed one-