Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nikhil Baliram Gaikwad"'
Autor:
Nikhil Baliram Gaikwad, Santosh Kumar Sahoo, Ojaswitha Ommi, Mohammad Naiyaz Ahmad, Afroz Pathan, Grace Kaul, Srinivas Nanduri, Arunava Dasgupta, Sidharth Chopra, Venkata Madhavi Yaddanapudi
Publikováno v:
ChemistrySelect. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f58cfe4ebf33f65d49f3a87222760f22
https://doi.org/10.1002/slct.202203333
https://doi.org/10.1002/slct.202203333
Autor:
Nanduri Srinivas, Shankar Biradar, Nikhil Baliram Gaikwad, Chandraiah Godugu, Venkata Madhavi Yaddanapudi, Mayuri Ban, Sapana Bansode
Publikováno v:
Archiv der PharmazieREFERENCES. 354(11)
A series of 1,2,3-triazole derivatives based on the quinoline-benzimidazole hybrid scaffold was designed, synthesized, and screened against a panel of NCI-60 humanoid cancer cell lines for in vitro cytotoxicity evaluation, which revealed that compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d047e56d564550f6bb285ca7c78ff7
https://pubmed.ncbi.nlm.nih.gov/34346099
https://pubmed.ncbi.nlm.nih.gov/34346099
Autor:
Veera Ganesh Yerra, Nikhil Baliram Gaikwad, Anil Kumar Kalvala, Srinivas Nanduri, Y.V. Madhavi, Ashutosh Kumar
Publikováno v:
Current Medicinal Chemistry. 26:5207-5229
Adenosine 5′-monophosphate activated protein kinase (AMPK) is a key enzymatic protein involved in linking the energy sensing to the metabolic manipulation. It is a serine/threonine kinase activated by several upstream kinases. AMPK is a heterotrime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640ece01bde1ec50fe998adee10be337
https://doi.org/10.2174/0929867325666180406120051
https://doi.org/10.2174/0929867325666180406120051
Autor:
Ramana Garise, Nikhil Baliram Gaikwad, Chandraiah Godugu, Venkata Madhavi Yaddanapudi, Nanduri Srinivas, Sapana Bansod, Alekhya Mara
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 49:128294
A library of new 3-phenylisoxazolo[5,4–d]pyrimidines (8–10) was designed based on a scaffold hybridization technique incorporating the important pharmacophoric features of 4-aminopyrimidine and phenyl isoxazole scaffold which is renowned for its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960d53939cafc1e1801198f2ac61ee36
https://doi.org/10.1016/j.bmcl.2021.128294
https://doi.org/10.1016/j.bmcl.2021.128294
Autor:
Santosh K. Sahoo, Venkata Madhavi Yaddanapudi, Arunava Dasgupta, Mohammad Naiyaz Ahmad, Srinivas Nanduri, G. Kaul, Bandela Rani, Nikhil Baliram Gaikwad, Manjulika Shukla, Sidharth Chopra
Publikováno v:
European Journal of Medicinal Chemistry. 222:113580
In search of novel therapeutic agents active against emerging drug-resistant Mycobacterium tuberculosis and to counter the long treatment protocol of existing drugs, herein we present synthesis and biological evaluation of a new series of 5-phenyl-3-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309ac19e7a2c912fda60b97f68ce6ea5
https://doi.org/10.1016/j.ejmech.2021.113580
https://doi.org/10.1016/j.ejmech.2021.113580
Autor:
Sidharth Chopra, Nikhil Baliram Gaikwad, Pathan Afroz, Srinivas Nanduri, Venkata Madhavi Yaddanapudi, Grace Kaul, Manjulika Shukla, Arunava Dasgupta, Mohammad N. Ahmad
Publikováno v:
Journal of Molecular Structure. 1227:129545
A new series of 3-phenyl-4,5-dihydroisoxazole-5-carboxamides were designed, synthesized, and evaluated for their potency against Mtb H37Rv. Designed molecules were synthesized by one-pot cycloaddition reaction in good to excellent yields. Anti-Tuberc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38bffa3ae4a3934ee5297b41308f2e49
https://doi.org/10.1016/j.molstruc.2020.129545
https://doi.org/10.1016/j.molstruc.2020.129545
Autor:
Krishna Nirmale, Manjulika Shukla, Arunava Das Gupta, Sidharth Chopra, Madhavi Venkata Yaddanapudi, Grace Kaul, Mohammad N. Ahmad, Srinivas Nanduri, Santosh K. Sahoo, Nikhil Baliram Gaikwad
Publikováno v:
Archiv der Pharmazie. 354:2000349
Mycobacterium tuberculosis (Mtb) is one of the most dangerous pathogens affecting immunocompetent and immunocompromised patients worldwide. Novel molecules, which are efficient and can reduce the duration of therapy against drug-resistant strains, ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c18305886e36f18ea1d605b6844a33
https://doi.org/10.1002/ardp.202000349
https://doi.org/10.1002/ardp.202000349
Publikováno v:
European Journal of Medicinal Chemistry. 181:111561
The cinnamamide (cinnamic acid amide and cinnamide) is a privileged scaffold present widely in a number of natural products. The scaffold acts as a useful template for designing and arriving at newly drug-like molecules with potential pharmacological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0b40667df6bcc9cd80284130312de8
https://doi.org/10.1016/j.ejmech.2019.07.064
https://doi.org/10.1016/j.ejmech.2019.07.064