Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Nik N. L. Kruisbergen"'
Autor:
Nik N. L. Kruisbergen, Irene Di Ceglie, Yvonne van Gemert, Birgitte Walgreen, Monique M. A. Helsen, Annet W. Slöetjes, Marije I. Koenders, Fons A. J. van de Loo, Johannes Roth, Thomas Vogl, Peter M. van der Kraan, Arjen B. Blom, Peter L. E. M. van Lent, Martijn H. J. van den Bosch
Publikováno v:
Antioxidants, Vol 10, Iss 11, p 1660 (2021)
Osteoarthritis (OA) is a destructive disease of the joint with age and obesity being its most important risk factors. Around 50% of OA patients suffer from inflammation of the synovial joint capsule, which is characterized by increased abundance and
Externí odkaz:
https://doaj.org/article/78cf3de17a744173a88dbeea58163c1d
Autor:
Nik N L Kruisbergen, Yvonne van Gemert, Arjen B Blom, Martijn H J van den Bosch, Peter L E M van Lent
Publikováno v:
Rheumatology, 62, 42-51
Rheumatology, 62, 1, pp. 42-51
Rheumatology, 62, 1, pp. 42-51
Contains fulltext : 287600.pdf (Publisher’s version ) (Open Access) Synovial macrophages are key mediators of OA pathology, and skewing of macrophage phenotype in favour of an M1-like phenotype is thought to underlie the chronicity of synovial infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd9b171a89bf312bebe2734d23b0a6d2
http://hdl.handle.net/2066/287600
http://hdl.handle.net/2066/287600
Autor:
Giuliana, Ascone, Irene, Di Ceglie, Martijn H J, van den Bosch, Nik N L, Kruisbergen, Birgitte, Walgreen, Annet W, Sloetjes, Ernst, Lindhout, Leo A B, Joosten, Fons A J, van de Loo, Marije I, Koenders, Peter M, van der Kraan, Arjen B, Blom, Peter L E M, van Lent
Publikováno v:
Clinical and experimental rheumatology. 37(6)
In this study, we used hypercholesterolaemic apolipoprotein E-deficient (Apoe-/-) mice to investigate LDL/oxLDL effect on synovial inflammation and cartilage destruction during antigen-induced arthritis (AIA). Further, as macrophage FcγRs are crucia