Dietary LPC-Bound n -3 LCPUFA Protects against Neonatal Brain Injury in Mice but Does Not Enhance Stem Cell Therapy.

Autor: Hermans EC; Department for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, 3508 AB Utrecht, The Netherlands., van Gerven CCE; Department for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, 3508 AB Utrecht, The Netherlands., Johnsen L; Aker BioMarine Human Ingredients AS, Oksenøyveien 10, 1327 Lysaker, Norway., Tungen JE; Aker BioMarine Human Ingredients AS, Oksenøyveien 10, 1327 Lysaker, Norway., Nijboer CH; Department for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, 3508 AB Utrecht, The Netherlands., de Theije CGM; Department for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, 3508 AB Utrecht, The Netherlands.

Publikováno v: Nutrients [Nutrients] 2024 Jul 12; Vol. 16 (14). Date of Electronic Publication: 2024 Jul 12.

Modifying the Secretome of Mesenchymal Stem Cells Prolongs the Regenerative Treatment Window for Encephalopathy of Prematurity.

Autor: Vaes JEG; Department for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, 3508 AB Utrecht, The Netherlands.; Department of Neonatology, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, 3508 AB Utrecht, The Netherlands., Onstwedder SM; Department for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, 3508 AB Utrecht, The Netherlands., Trayford C; Department of Instructive Biomaterials Engineering, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, 6229 ER Maastricht, The Netherlands., Gubbins E; Department of Instructive Biomaterials Engineering, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, 6229 ER Maastricht, The Netherlands., Maas M; Department for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, 3508 AB Utrecht, The Netherlands., van Rijt SH; Department of Instructive Biomaterials Engineering, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, 6229 ER Maastricht, The Netherlands., Nijboer CH; Department for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, 3508 AB Utrecht, The Netherlands.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 12; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 12.

Feasibility and safety of intranasally administered mesenchymal stromal cells after perinatal arterial ischaemic stroke in the Netherlands (PASSIoN): a first-in-human, open-label intervention study.

Autor: Baak LM; Department of Neonatology, University Medical Center, Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, Netherlands., Wagenaar N; Department of Neonatology, University Medical Center, Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, Netherlands., van der Aa NE; Department of Neonatology, University Medical Center, Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, Netherlands., Groenendaal F; Department of Neonatology, University Medical Center, Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, Netherlands., Dudink J; Department of Neonatology, University Medical Center, Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, Netherlands., Tataranno ML; Department of Neonatology, University Medical Center, Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, Netherlands., Mahamuud U; Department of Neonatology, University Medical Center, Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, Netherlands., Verhage CH; Child Development and Exercise Center, University Medical Center, Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, Netherlands., Eijsermans RMJC; Child Development and Exercise Center, University Medical Center, Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, Netherlands., Smit LS; Department of Neurology, Erasmus MC-Sophia Children's Hospital, Rotterdam, Netherlands., Jellema RK; Department of Neonatology, Maastricht University Medical Center, Maastricht, Netherlands., de Haan TR; Department of Neonatology, Emma Children's Hospital, Academic Medical Center, Amsterdam University Medical Center, Amsterdam, Netherlands., Ter Horst HJ; Department of Neonatology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, Netherlands., de Boode WP; Department of Neonatology, Radboud University Medical Center, Radboud Institute for Health Sciences, Amalia Children's Hospital, Nijmegen, Netherlands., Steggerda SJ; Department of Neonatology, Willem-Alexander Children's Hospital, Leiden University Medical Center, Leiden, Netherlands., Prins HJ; Cell Therapy Facility, Pharmacy Department, University Medical Center Utrecht, Utrecht, Netherlands., de Haar CG; Cell Therapy Facility, Pharmacy Department, University Medical Center Utrecht, Utrecht, Netherlands., de Vries LS; Department of Neonatology, University Medical Center, Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, Netherlands., van Bel F; Department of Neonatology, University Medical Center, Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, Netherlands., Heijnen CJ; Department of Symptom Research, Division of Internal Medicine, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Nijboer CH; Department for Developmental Origins of Disease, University Medical Center, Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, Netherlands., Benders MJNL; Department of Neonatology, University Medical Center, Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, Netherlands. Electronic address: m.benders@umcutrecht.nl.

Publikováno v: The Lancet. Neurology [Lancet Neurol] 2022 Jun; Vol. 21 (6), pp. 528-536.

Nutritional Supplementation Reduces Lesion Size and Neuroinflammation in a Sex-Dependent Manner in a Mouse Model of Perinatal Hypoxic-Ischemic Brain Injury.

Autor: Brandt MJV; Department for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, 3508 AB Utrecht, The Netherlands., Nijboer CH; Department for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, 3508 AB Utrecht, The Netherlands., Nessel I; Centre for Neuroscience, Surgery and Trauma, Blizard Institute, Queen Mary University of London, London E1 2AD, UK., Mutshiya TR; Centre for Neuroscience, Surgery and Trauma, Blizard Institute, Queen Mary University of London, London E1 2AD, UK., Michael-Titus AT; Centre for Neuroscience, Surgery and Trauma, Blizard Institute, Queen Mary University of London, London E1 2AD, UK., Counotte DS; Danone Nutricia Research, 3508 TC Utrecht, The Netherlands., Schipper L; Danone Nutricia Research, 3508 TC Utrecht, The Netherlands., van der Aa NE; Department of Neonatology, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, 3508 AB Utrecht, The Netherlands., Benders MJNL; Department of Neonatology, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, 3508 AB Utrecht, The Netherlands., de Theije CGM; Department for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, 3508 AB Utrecht, The Netherlands.

Publikováno v: Nutrients [Nutrients] 2021 Dec 30; Vol. 14 (1). Date of Electronic Publication: 2021 Dec 30.

The impact of trophic and immunomodulatory factors on oligodendrocyte maturation: Potential treatments for encephalopathy of prematurity.

Autor: Vaes JEG; Department for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, The Netherlands.; Department of Neonatology, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, The Netherlands., Brandt MJV; Department for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, The Netherlands., Wanders N; Department for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, The Netherlands., Benders MJNL; Department of Neonatology, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, The Netherlands., de Theije CGM; Department for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, The Netherlands., Gressens P; Université de Paris, NeuroDiderot, INSERM, Paris, France., Nijboer CH; Department for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, Utrecht, The Netherlands.

Publikováno v: Glia [Glia] 2021 Jun; Vol. 69 (6), pp. 1311-1340. Date of Electronic Publication: 2020 Nov 30.