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Publikováno v:
Medicinal Chemistry Research. 25:70-82
Synthesis, physicochemical characterization and pharmacological evaluation of mutual prodrugs of aceclofenac with quercetin, vanillin and l-tryptophan have been attempted to develop novel gastrosparing NSAIDs, devoid of ulcerogenic side effects. The
Publikováno v:
Medicinal Chemistry Research; Jan2016, Vol. 25 Issue 1, p70-82, 13p
Recent Advancement in ProdrugsDrugs used as medicines have many limitations like low chemical stability, aqueous solubility, or oral absorption/bioavailability, rapid presystemic metabolism, toxicity, inadequate site specificity, or poor patient acce