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Cell-cell and cell-matrix adhesion in survival and metastasis: Stat3 versus Akt

Autor: Niit Maximilian, Hoskin Victoria, Carefoot Esther, Geletu Mulu, Arulanandam Rozanne, Elliott Bruce, Raptis Leda

Publikováno v: Biomolecular Concepts, Vol 6, Iss 5-6, Pp 383-399 (2015)

Both cell-cell and cell-matrix adhesion are important for epithelial cell differentiation and function. Classical cadherins mediate cell to cell interactions and are potent activators of the signal transducer and activator of transcription (Stat3), t

Externí odkaz: https://doaj.org/article/00917ca29e434905ab630893fcc1feb9

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Modulation of Akt vs Stat3 activity by the focal adhesion kinase in non-neoplastic mouse fibroblasts.

Autor: Geletu M; Department of Biomedical and Molecular Sciences and Department of Pathology and Molecular Mdicine, Queen's University, Kingston, ON, K7L 3N6, Canada. Electronic address: mulu.geletu@utoronto.ca., Adan H; Department of Biomedical and Molecular Sciences and Department of Pathology and Molecular Mdicine, Queen's University, Kingston, ON, K7L 3N6, Canada., Niit M; Department of Biomedical and Molecular Sciences and Department of Pathology and Molecular Mdicine, Queen's University, Kingston, ON, K7L 3N6, Canada., Arulanandam R; Department of Biomedical and Molecular Sciences and Department of Pathology and Molecular Mdicine, Queen's University, Kingston, ON, K7L 3N6, Canada., Carefoot E; Department of Biomedical and Molecular Sciences and Department of Pathology and Molecular Mdicine, Queen's University, Kingston, ON, K7L 3N6, Canada., Hoskin V; Department of Biomedical and Molecular Sciences and Department of Pathology and Molecular Mdicine, Queen's University, Kingston, ON, K7L 3N6, Canada., Sina D; Department of Biomedical and Molecular Sciences and Department of Pathology and Molecular Mdicine, Queen's University, Kingston, ON, K7L 3N6, Canada., Elliott B; Department of Biomedical and Molecular Sciences and Department of Pathology and Molecular Mdicine, Queen's University, Kingston, ON, K7L 3N6, Canada., Gunning P; Department of Biomedical and Molecular Sciences and Department of Pathology and Molecular Mdicine, Queen's University, Kingston, ON, K7L 3N6, Canada., Raptis L; Department of Biomedical and Molecular Sciences and Department of Pathology and Molecular Mdicine, Queen's University, Kingston, ON, K7L 3N6, Canada.

Publikováno v: Experimental cell research [Exp Cell Res] 2022 Feb 01; Vol. 411 (1), pp. 112731. Date of Electronic Publication: 2021 Jul 14.