Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Niina Bhattarai"'
Rapid and robust patterns of spontaneous locomotor deficits in mouse models of Huntington's disease.
Autor:
Taneli Heikkinen, Timo Bragge, Niina Bhattarai, Teija Parkkari, Jukka Puoliväli, Outi Kontkanen, Patrick Sweeney, Larry C Park, Ignacio Munoz-Sanjuan
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243052 (2020)
Huntington's disease (HD) is an inherited neurodegenerative disorder characterized by severe disruption of cognitive and motor functions, including changes in posture and gait. A number of HD mouse models have been engineered that display behavioral
Externí odkaz:
https://doaj.org/article/07aa52b632ac417abd3cbd33a4065cef
Publikováno v:
Cells, Vol 10, Iss 6, p 1405 (2021)
Age-related macular degeneration (AMD) is a retinal disease leading to impaired vision. Cigarette smoke increases the risk for developing AMD by causing increased reactive oxygen species (ROS) production and damage in the retinal pigment epithelium (
Externí odkaz:
https://doaj.org/article/9ccd415fc8294cdf8b9ba4ab7e7a0326
Autor:
Niina Bhattarai, Niina Piippo, Sofia Ranta-aho, Yashavanthi Mysore, Kai Kaarniranta, Anu Kauppinen
Publikováno v:
Antioxidants, Vol 10, Iss 1, p 67 (2021)
Age-related macular degeneration (AMD) is an eye disease in which retinal pigment epithelium (RPE) cells play a crucial role in maintaining retinal homeostasis and photoreceptors’ functionality. During disease progression, there is increased inflam
Externí odkaz:
https://doaj.org/article/cbc8eee749bb40c09325e97c98cec582
Publikováno v:
Acta Ophthalmologica. 100
Publikováno v:
Acta Ophthalmologica. 100
Autor:
Maria Hytti, Johanna Ruuth, Iiris Kanerva, Niina Bhattarai, Maria L. Pedersen, Carsten U. Nielsen, Anu Kauppinen
Publikováno v:
Molecular and cellular biochemistry.
During age-related macular degeneration (AMD), chronic inflammatory processes, possibly fueled by high glucose levels, cause a breakdown of the retinal pigment epithelium (RPE), leading to vision loss. Phloretin, a natural dihydroxychalcone found in
Autor:
Niina Bhattarai, Maria Hytti, Mika Reinisalo, Kai Kaarniranta, Yashavanthi Mysore, Anu Kauppinen
Publikováno v:
Immunologic research. 70(5)
In addition to hypoxia, inflammation is capable of inducing vascular endothelial growth factor (VEGF) expression in human retinal pigment epithelial (RPE) cells. Excessive levels of VEGF promote choroidal neovascularization and thereby contribute to
Publikováno v:
Acta Ophthalmologica. 100
Publikováno v:
Acta Ophthalmologica. 100
Prolyl oligopeptidase inhibitor KYP‐2047 alleviates inflammation in retinal pigment epithelium cells
Autor:
Maria Hytti, Niina Bhattarai, Eveliina Korhonen, Anu Kauppinen, Sofia Ranta-aho, Maija Toppila
Publikováno v:
Acta Ophthalmologica. 99