Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Niharika Gaur"'
Autor:
Bisrat T. Woldemichael, Ali Jawaid, Eloïse A. Kremer, Niharika Gaur, Jacek Krol, Antonin Marchais, Isabelle M. Mansuy
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Protein phosphatase1 (PP1), a signalling and transcriptional regulator, and epigenetic modulator is known to be a memory suppressor. Here the authors show that memory control by PP1 involves the microRNA cluster miR-183/96/182, and that this cluster
Externí odkaz:
https://doaj.org/article/5816002235934ac5bb09374f878e2f62
Autor:
Eric A. Miska, Pierre-Luc Germain, Niharika Gaur, Katharina Gapp, Isabelle M. Mansuy, Anastasiia Efimova, Ali Jawaid, Deepak K. Tanwar, Nicola Zamboni, Gretchen van Steenwyk, Francesca Manuella, Kristina M. Thumfart
Publikováno v:
The EMBO Journal
The EMBO Journal, 39 (23)
The EMBO Journal, 39 (23)
Environmental factors can change phenotypes in exposed individuals and offspring and involve the germline, likely via biological signals in the periphery that communicate with germ cells. Here, using a mouse model of paternal exposure to traumatic st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f932882279fa18f4b83b13b8199619
https://doi.org/10.5167/uzh-194069
https://doi.org/10.5167/uzh-194069
Publikováno v:
bioRxiv
In mammals, spermatogonial cells exit quiescence immediately after birth and initiate a life-long equilibrium between proliferation and differentiation for the production of spermatogenic cells and functional sperm. Although it is generally accepted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e317e50e57c7050bbfa25bbe885644
https://www.zora.uzh.ch/id/eprint/214465/
https://www.zora.uzh.ch/id/eprint/214465/
Autor:
Olivia Engmann, Niharika Gaur, Johannes Bohacek, Isabelle M. Mansuy, Eloïse A. Kremer, Melissa A. Lee
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, 8 (1)
Scientific Reports
Scientific Reports, 8 (1)
Scientific Reports
5-hydroxymethylation (5-hmC) is an epigenetic modification on DNA that results from the conversion of 5-methylcytosine by Ten-Eleven Translocation (TET) proteins. 5-hmC is widely present in the brain and is subjected to dynamic regulation during deve
Autor:
Isabelle M. Mansuy, Ali Jawaid, Magdalini Polymenidou, Niharika Gaur, Tariq Afroz, Florent Laferrière, Bisrat T. Woldemichael, Eloïse A. Kremer
Publikováno v:
Molecular Neurobiology
Molecular Neurobiology, Humana Press, 2019, 56 (5), pp.3451-3462. ⟨10.1007/s12035-018-1314-3⟩
Molecular Neurobiology, Humana Press, 2019, 56 (5), pp.3451-3462. ⟨10.1007/s12035-018-1314-3⟩
International audience; Aging is characterized by progressive memory decline that can lead to dementia when associated with neurodegeneration. Here, we show in mice that aging-related memory decline involves defective biogenesis of microRNAs (miRNAs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004224d0fa7bd199ee16940f6c61344f
https://hal.archives-ouvertes.fr/hal-03403398
https://hal.archives-ouvertes.fr/hal-03403398
Autor:
Ali Jawaid, Eloïse A. Kremer, Bisrat T. Woldemichael, Jacek Krol, Niharika Gaur, Antonin Marchais, Isabelle M. Mansuy
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nature Communications, 7
Nature Communications
Nature Communications, 7
Nature Communications
Memory formation is a complex cognitive function regulated by coordinated synaptic and nuclear processes in neurons. In mammals, it is controlled by multiple molecular activators and suppressors, including the key signalling regulator, protein phosph
Publikováno v:
2018 Second International Conference on Computing Methodologies and Communication (ICCMC).
Advent of Cyber has converted the entire World into a Global village. But, due to vurneabilites in SCADA architecture [1] national assests are more prone to cyber attacks.. Cyber invasions have a catastrophic effect in the minds of the civilian popul
Autor:
Niharika Gaur, Emmanuel Karouzakis, Selene Glück, Edvardas Bagdonas, Astrid Jüngel, Beat A Michel, Renate E Gay, Steffen Gay, Mojca Frank-Bertoncelj, Michel Neidhart
Publikováno v:
RMD Open
Background The DNA of rheumatoid arthritis synovial fibroblasts (RASF) is globally hypomethylated; this contributes to an aggressive behaviour. In an attempt to remethylate these cells, we supplemented with methyl donors. We investigated the possible
Autor:
Andrea Morger, Fredrik Svensson, Staffan Arvidsson McShane, Niharika Gauraha, Ulf Norinder, Ola Spjuth, Andrea Volkamer
Publikováno v:
Journal of Cheminformatics, Vol 13, Iss 1, Pp 1-14 (2021)
Abstract Machine learning methods are widely used in drug discovery and toxicity prediction. While showing overall good performance in cross-validation studies, their predictive power (often) drops in cases where the query samples have drifted from t
Externí odkaz:
https://doaj.org/article/8fe425216aae4b26b97229dddbe63ab8