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pro vyhledávání: '"Nihar J. Mehta"'
Publikováno v:
Cells, Vol 8, Iss 1, p 59 (2019)
Parkinson’s disease, like other neurodegenerative diseases, exhibits two common features: Proteinopathy and oxidative stress, leading to protein aggregation and mitochondrial damage respectively. Because both protein aggregates and dysfunctional mi
Externí odkaz:
https://doaj.org/article/76a1e2455e1e4efd967c04cb8acd1e5e
Autor:
Meredith M. Njus, Ashraf H. Saleh, Karen A. Beningo, David Njus, Karam Asmaro, Nihar J. Mehta, David J. Hermiz
Publikováno v:
Free Radical Biology and Medicine. 101:44-52
The dopamine oxidation product cysteinyl-dopamine has attracted attention as a contributor to the death of dopaminergic neurons in Parkinson's disease. Treatment of cysteinyl-dopamine with hypochlorite yields an even more cytotoxic product. This prod
Publikováno v:
Cells
Cells, Vol 8, Iss 1, p 59 (2019)
Cells, Vol 8, Iss 1, p 59 (2019)
Parkinson’s disease, like other neurodegenerative diseases, exhibits two common features: Proteinopathy and oxidative stress, leading to protein aggregation and mitochondrial damage respectively. Because both protein aggregates and dysfunctional mi
Autor:
Nihar J. Mehta, David Njus
Publikováno v:
Biophysical Journal. (2):184a
Parkinson's disease is a progressive neurodegenerative disorder caused by the loss of dopaminergic neurons, but what causes the death of these neurons is unknown. Although oxidative stress, mitochondrial dysfunction, dopamine oxidation and microglial