Výsledky vyhledávání - "Nihan Korkmaz"

Akademický článek

Sleep Problems and Influencing Factors in Children Aged 0-3 Years

Autor: Merve AZAK, Nihan KORKMAZ, Kadriye ŞAHİN, Serap BALCI

Publikováno v: Bezmiâlem Science, Vol 12, Iss 2, Pp 231-238 (2024)

Objective: The aim of this study was to identify sleep problems in children aged 0-3 years and the factors influencing them. Methods: This descriptive correlational study was conducted online with 366 parents of children aged 0-3 years. Children’s

Externí odkaz: https://doaj.org/article/62a57a09074a4568b1dcc175e7a45010

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Synthesis and Anticancer Potential of New Hydroxamic Acid Derivatives as Chemotherapeutic Agents

Autor: Işıl Nihan Korkmaz, Hasan Özdemir

Publikováno v: Applied Biochemistry and Biotechnology. 194:6349-6366

Histone deacetylase (HDAC) inhibitors have been shown to induce differentiation, cell cycle arrest, and apoptosis due to their low toxicity, inhibiting migration, invasion, and angiogenesis in many cancer cells. Studies show that hydroxamic acids are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e43c0f32780d1c2450edb9e0ea68385
https://doi.org/10.1007/s12010-022-04107-z

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In Vitro Inhibition Effects of 2-Amino Thiazole Derivatives on Lactoperoxidase Enzyme Activity

Autor: Işıl Nihan KORKMAZ

Publikováno v: Volume: 43, Issue: 1 33-37
Cumhuriyet Science Journal

Lactoperoxidase (LPO E.C. 1.11.1.7) is a member of the peroxidase family and is an important glycoprotein containing heme group in its structure and showing the antimicrobial effect on disease causing microorganisms in the digestive system of newborn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02375283c24b9463d12b4e78c7578989
https://doi.org/10.17776/csj.1017247

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YouTube as a source of information about COVID-19 for children: Content quality, reliability, and audience participation analysis

Autor: Nihan Korkmaz, Suzan Yildiz, Kadriye Şahin, Merve Azak

Publikováno v: Journal of Pediatric Nursing

Purpose This study aimed to evaluate the content quality, reliability, and audience participation analysis of YouTube videos as a source of information about COVID-19 for children. Design and methods This study was conducted in a descriptive design.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d44888bf8cd07a76eea91eed7771da6
https://doi.org/10.1016/j.pedn.2021.06.024

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Methyl benzoate derivatives: in vitro Paraoxonase 1 inhibition and in silico studies

Autor: Işıl Nihan Korkmaz, Cüneyt Türkeş, Yeliz Demir, Hasan Özdemir, Şükrü Beydemir

Publikováno v: Journal of biochemical and molecular toxicologyREFERENCES. 36(10)

Paraoxonase 1 (PON1) can metabolize some compounds such as aromatic carboxylic acid and unsaturated aliphatic esters, arylesters, cyclic carbonate, plucuronide drugs, some carbamate insecticide classes, nerve gases, and lactone compounds. Methyl benz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa9525ca6b25f6054b20843a33fe4bf
https://pubmed.ncbi.nlm.nih.gov/35708184

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2-Amino thiazole derivatives as inhibitors of some metabolic enzymes: An in vitro and in silico study

Autor: Işıl Nihan KORKMAZ

Publikováno v: Biotechnology and applied biochemistryREFERENCES.

The thiazole derivatives are desirable compounds in the evaluation of their biological activities such as antiprotozoal antibacterial, antifungal, antituberculosis. Considering the medical application potential of 2-amino thiazole compounds, we aimed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a23d53a16855a5c6e0c722d502abdede
https://pubmed.ncbi.nlm.nih.gov/35857901

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Biological evaluation and in silico study of benzohydrazide derivatives as paraoxonase 1 inhibitors

Autor: Işıl Nihan Korkmaz, Cüneyt Türkeş, Yeliz Demir, Aykut Öztekin, Hasan Özdemir, Şükrü Beydemir

Serum paraoxonase 1 (PON1) is found in all mammalian species and is a calcium-dependent hydrolytic enzyme. PON1 hydrolyze several substrates, including carbonates, esters, and organophosphates. In the current study, we aimed to investigate the effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d03ee2c36be8bba9fffe430cdde15ae
https://hdl.handle.net/20.500.12501/2642

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In vitro Inhibition Profiles and Molecular Docking Analysis of Benzohydrazide Derivatives on Red Blood Cell Carbonic Anhydrases Isozymes

Autor: Pınar Güller, Işıl Nihan Korkmaz, Ramazan Kalın, Aykut Öztekin, Hasan Özdemir

Background: Carbonic anhydrases (CAs, EC 4.2.1.1) are metalloenzymes that contain zinc ions on the active side and convert carbon dioxide to bicarbonate in metabolism. Human CA-I and CA-II, which are the most abundant CA isozymes in erythrocytes, hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f925b953fd70b8931a6c5c8f772a46
https://hdl.handle.net/20.500.12501/3062

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A New Affinity Matrixe Synthesized from Aminobenzohydrazide Derivatives for Purification of Lactoperoxidase Enzyme

Autor: Neslihan Macit Kavaz, Deniz Erel, Işıl Nihan Korkmaz, Serpil Gerni, Nurgül Abul, Songül Bayrak, Zeynep Köksal, Ramazan Kalın, Aykut Öztekin, Hasan Özdemir

In this study, a new affinity process was developed for the purification of Lactoperoxidase with synthesized sixteen aminobenzohydrazide derivatives. For this purpose, ligands were covalently bound to CNBr-activated Sepharose-4B-L-tyrosine matrix and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a88584cf934d18974c47615f3b963a0
https://hdl.handle.net/20.500.12501/2664

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