Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nihan Kavaslar"'
Autor:
Martin F. Gerrits, Sujoy Ghosh, Nihan Kavaslar, Benjamin Hill, Anastasia Tour, Erin L. Seifert, Brittany Beauchamp, Shelby Gorman, Joan Stuart, Robert Dent, Ruth McPherson, Mary-Ellen Harper
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 8, Pp 2394-2404 (2010)
Inter-individual variability in weight gain and loss under energy surfeit and deficit conditions, respectively, are well recognized but poorly understood phenomena. We documented weight loss variability in an intensively supervised clinical weight lo
Externí odkaz:
https://doaj.org/article/26fc79bb8a5248e388f5d32acb63e61e
Autor:
Sheila R Costford, Nihan Kavaslar, Nadav Ahituv, Shehla N Chaudhry, Wendy S Schackwitz, Robert Dent, Len A Pennacchio, Ruth McPherson, Mary-Ellen Harper
Publikováno v:
PLoS ONE, Vol 2, Iss 9, p e903 (2007)
BACKGROUND: AMP-activated protein kinase (AMPK) is a heterotrimeric enzyme that is evolutionarily conserved from yeast to mammals and functions to maintain cellular and whole body energy homeostasis. Studies in experimental animals demonstrate that a
Externí odkaz:
https://doaj.org/article/22da3f04b3e14d769dfdc61b330d197c
Autor:
Sujoy Ghosh, Benjamin Hill, Ruth McPherson, Erin L. Seifert, Brittany Beauchamp, Shelby A. Gorman, Nihan Kavaslar, Martin F. Gerrits, Joan S. Stuart, Anastasia Tour, Robert Dent, Mary-Ellen Harper
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 8, Pp 2394-2404 (2010)
Inter-individual variability in weight gain and loss under energy surfeit and deficit conditions, respectively, are well recognized but poorly understood phenomena. We documented weight loss variability in an intensively supervised clinical weight lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef2f75df7bab0e198f44c28aab5bdb1
https://doi.org/10.1194/jlr.p005298
https://doi.org/10.1194/jlr.p005298
Autor:
Robert S. Kiss, Nihan Kavaslar, Keiichiro Okuhira, Yves L. Marcel, Ross W. Milne, Stephanie Walter, Mason W. Freeman, Ruth McPherson
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 27:1139-1145
Objective— We have used a multitiered approach to identify genetic and cellular contributors to high-density lipoprotein (HDL) deficiency in 124 human subjects. Methods and Results— We resequenced 4 candidate genes for HDL regulation and identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb824d10bd4106a954de3024c67696a3
https://doi.org/10.1161/atvbaha.106.137646
https://doi.org/10.1161/atvbaha.106.137646
Autor:
Ruth McPherson, Jonathan Cohen, Heather Doelle, Sybil Hébert, Li Weng, Wendy Schackwitz, Anna Ustaszewska, Len A. Pennacchio, Nihan Kavaslar
Publikováno v:
Journal of Clinical Investigation. 115:1016-1020
Mutations in MEF2A have been implicated in an autosomal dominant form of coronary artery disease (adCAD1). In this study we sought to determine whether severe mutations in MEF2A might also explain sporadic cases of coronary artery disease (CAD). To d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19d3bf4d6cd3cf90ba5b3457c8e6c40e
https://doi.org/10.1172/jci24186
https://doi.org/10.1172/jci24186
Publikováno v:
Journal of Biological Chemistry. 276:48823-48830
The concept that selective transfer of high density lipoprotein (HDL)-derived cholesteryl esters (CE) does not require lipoprotein internalization has been challenged recently by evidence that implicates HDL recycling during the selective uptake proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc3df617095e8c983e1beef9a0d33b8
https://doi.org/10.1074/jbc.m103954200
https://doi.org/10.1074/jbc.m103954200
Publikováno v:
The American Journal of Human Genetics. 66:1705-1709
We studied a large consanguineous Anatolian family with children who exhibited hydranencephaly associated with microcephaly. The children were severely affected. This novel genetic disorder is autosomal recessive. We used autozygosity mapping to iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afebbbc9ba15586a9c90f6eef9b0bac5
https://doi.org/10.1086/302898
https://doi.org/10.1086/302898
Autor:
Alexandre F Stewart, Ruth McPherson, Li Chen, Kathryn Williams, Heather Doelle, Robbie Davies, Sonny Dandona, Nihan Kavaslar, Julie Ruthberg, Gwen Ewart, Rosemary LaRose, Lan Vo, Yanquing Wang, Paulina Lau, Marino Labinaz, Benjamin Chow, George A Wells, Robert Roberts
Publikováno v:
Circulation. 118
Background : Coronary artery disease (CAD) is the leading cause of death in the western world. The only common genetic risk locus identified to date by us and others in genome wide association studies (GWAS) resides at 9p21.3. Methods: The Ottawa Hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca5a701d2384841867aee358f4a2d7f0
https://doi.org/10.1161/circ.118.suppl_18.s_427-a
https://doi.org/10.1161/circ.118.suppl_18.s_427-a
Autor:
Alexandre F.R. Stewart, Robert Roberts, Ruth McPherson, George A. Wells, Kathryn Williams, Nihan Kavaslar
Publikováno v:
The Canadian journal of cardiology. 23
Background Coronary artery disease (CAD) remains the number one killer in the western world. Genetics accounts for greater than 50% of the risk for CAD. Genetic screening and early prevention in individuals identified as being at increased risk could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceeeb466fbfd45facdba88f744a0d5fe
https://pubmed.ncbi.nlm.nih.gov/17668082
https://pubmed.ncbi.nlm.nih.gov/17668082
Autor:
Alexandre F Stewart, Ruth McPherson, Kathryn Williams, Nihan Kavaslar, Julie Rutberg, Heather Doelle, Gwen Ewart, George Wells, Robert Roberts
Publikováno v:
Circulation. 116
Purpose: To identify genes predisposing to Coronary Artery Disease (CAD). Methods: We selected the unbiased approach of using the genome wide scan association case control method. Using the Affymetrix 500K SNP array that that average a marker every 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d6eb6b1cc7e792aad2122c666d410e2
https://doi.org/10.1161/circ.116.suppl_16.ii_56
https://doi.org/10.1161/circ.116.suppl_16.ii_56