Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Nihan Erginel-Unaltuna"'
Autor:
Gamze Guven, Ebru Ozer, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Ebba Lohmann, Nihan Erginel-Unaltuna
Publikováno v:
Neurological Sciences and Neurophysiology, Vol 37, Iss 3, Pp 134-140 (2020)
Objectives: Several large-scale genome association studies have shown that variants in the “Clusterin”' (CLU) gene are important risk factors for Alzheimer's disease (AD). It has also been shown that plasma CLU levels were elevated in patients wi
Externí odkaz:
https://doaj.org/article/c0e97c767c7b4f3bb106637dbfd735ab
Autor:
Gamze Guven, Ebba Lohmann, Jose Bras, J Raphael Gibbs, Hakan Gurvit, Basar Bilgic, Hasmet Hanagasi, Patrizia Rizzu, Peter Heutink, Murat Emre, Nihan Erginel-Unaltuna, Walter Just, John Hardy, Andrew Singleton, Rita Guerreiro
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162592 (2016)
'Microtubule-associated protein tau' (MAPT), 'granulin' (GRN) and 'chromosome 9 open reading frame72' (C9ORF72) gene mutations are the major known genetic causes of frontotemporal dementia (FTD). Recent studies suggest that mutations in these genes m
Externí odkaz:
https://doaj.org/article/565a694955634103955bf34667d877b8
Autor:
Reijo Laaksonen, Günay Can, Mika Kähönen, Evrim Komurcu-Bayrak, Ayse Berna Yuzbasıogulları, Altan Onat, Nihan Erginel-Unaltuna, Nina Mononen, Terho Lehtimäki
Publikováno v:
Anatolian Journal of Cardiology, Vol 24, Iss 5, Pp 326-333 (2020)
Anatolian Journal of Cardiology
Anatolian Journal of Cardiology
WOS:000583273800010 PubMed ID: 33122478 Objective: TCF7L2 is a repressor and transactivator of genes, and its variants are strongly associated with diabetes. This study aimed to evaluate the sex-specific relationship between the most common TCF7L2 ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b706f5830b654738cd260c0d410365
https://jag.journalagent.com/z4/download_fulltext.asp?pdir=anatoljcardiol&un=AJC-57736
https://jag.journalagent.com/z4/download_fulltext.asp?pdir=anatoljcardiol&un=AJC-57736
Publikováno v:
Biochemical Genetics. 58:935-952
Polymorphisms in the ESR1 gene have been associated with obesity and lipid metabolism. There are also important sex-related differences in the prevalence of obesity and related phenotypes. Therefore, we aimed to interrogate the association of the ESR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b70690a8abfa84009ace15087100d7
https://doi.org/10.1007/s10528-020-09987-6
https://doi.org/10.1007/s10528-020-09987-6
Autor:
Ebru Özer, Hakan Gurvit, Başar Bilgiç, Hasmet Hanagasi, Nihan Erginel-Unaltuna, Gamze Guven, Ebba Lohmann
Publikováno v:
Neurological Sciences and Neurophysiology, Vol 37, Iss 3, Pp 134-140 (2020)
Neurological sciences and neurophysiology 37(3), 134-(2020). doi:10.4103/NSN.NSN_46_20
Neurological sciences and neurophysiology 37(3), 134-(2020). doi:10.4103/NSN.NSN_46_20
Objectives: Several large-scale genome association studies have shown that variants in the “Clusterin”' (CLU) gene are important risk factors for Alzheimer's disease (AD). It has also been shown that plasma CLU levels were elevated in patients wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ea6e2ead7aa71618480f76b35fb828
http://www.nsnjournal.org/article.asp?issn=2636-865X
http://www.nsnjournal.org/article.asp?issn=2636-865X
Autor:
Hasmet Hanagasi, Eren Vurgun, Ebru Özer, Ebba Lohmann, Gamze Guven, Nihan Erginel-Unaltuna, Başar Bilgiç, Hakan Gurvit
Publikováno v:
Molecular biology reports 46(2), 1701-1707 (2019). doi:10.1007/s11033-019-04619-8
Numerous genetic evidence has pointed out that variations in cholesterol-related genes may be associated with an Alzheimer’s disease (AD) risk. We aimed to investigate the association between polymorphisms in several cholesterol-related genes [APOA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8619d870cf38001c58b1b632495d4772
https://doi.org/10.1007/s11033-019-04619-8
https://doi.org/10.1007/s11033-019-04619-8
Publikováno v:
Molecular Biology Reports.
Coronary artery disease (CAD) which is a complex cardiovascular disease is the leading cause of death worldwide. The changing prevalence of the disease in different ethnic groups pointing out the genetic background of CAD. In this study, we aimed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703ce61a8e83d650ba5c8cd062998034
https://doi.org/10.1007/s11033-021-06393-y
https://doi.org/10.1007/s11033-021-06393-y
Autor:
Hasmet Hanagasi, Bedia Samanci, Cagla Donmez, Nihan Erginel-Unaltuna, Hakan Gurvit, Rukiye Aslan, Gamze Guven, Ebba Lohmann, Başar Bilgiç
Publikováno v:
Molecular biology reports 47(8), 5903-5909 (2020). doi:10.1007/s11033-020-05661-7
'Triggering receptor expressed on myeloid cells 2' (TREM2) gene is involved in Alzheimer's disease (AD) and TREM2 mRNA expression is known to be increased in the peripheral blood cells of AD patients. In this study, we examined the expression levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c1dd684fb2ca2d0a5fb2951382b9c5
https://pubmed.ncbi.nlm.nih.gov/32681391
https://pubmed.ncbi.nlm.nih.gov/32681391
Publikováno v:
Volume: 8, Issue: 2 58-61
Experimed
Experimed
DOI: 10.26650/experimed.2018.18004Objectives: Alzheimer’s disease (AD) is anirreversible, neurodegenerative disease with an increasing worldwideprevalence. Several different factors are known to play a role in itspathogenesis and genetic predisposi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d23efc7e44ef9cb2a19e6d7e9b0cb2
https://doi.org/10.26650/experimed.2018.18004
https://doi.org/10.26650/experimed.2018.18004
Autor:
Pekka J. Karhunen, Mika Kähönen, Sirkka Goebeler, Markus Perola, Tiina Luukkaala, Reijo Laaksonen, Nihan Erginel-Unaltuna, Antti Hervonen, Bilge Ozsait-Selcuk, Evrim Komurcu-Bayrak, Mikko Hurme, K. Kristiansson, Terho Lehtimäki, Nina Mononen, Marja Jylhä
Publikováno v:
Annals of Human Genetics. 83:34-45
Upstream transcription factor 1 (USF1) regulates the transcription of many genes related to cell and organism survival processes such as stress and immune response, regulation of cellular senesce, and carcinogenesis. In this study, our aim was to inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ce882635e2d0c6a5aef6941b896ad1
https://doi.org/10.1111/ahg.12282
https://doi.org/10.1111/ahg.12282