Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Nihan ÇARÇAK"'
Autor:
Aylin Toplu, Nursima Mutlu, Elif Tuğçe Erdeve, Özge Sariyildiz, Musa Çelik, Devrim Öz-Arslan, Özlem Akman, Zoltan Molnár, Nihan Çarçak, Filiz Onat
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionOrexin is a neuropeptide neurotransmitter that regulates the sleep/wake cycle produced by the lateral hypothalamus neurons. Recent studies have shown the involvement of orexin system in epilepsy. Limited data is available about the possib
Externí odkaz:
https://doaj.org/article/34af1394138e4e5db5a066643e6cfa71
Autor:
Şura Akat Pişkin, Hande Yüceer Korkmaz, Canan Aysel Ulusoy, Elif Şanlı, Cem Ismail Küçükali, Filiz Onat, Erdem Tüzün, Nihan Çarçak
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ObjectiveAutoimmune encephalitis (AE) is a distinct neuro-immunological disorder associated with the production of autoantibodies against neuronal proteins responsible for pharmacoresistant seizures, cognitive decline and behavioral problems. To esta
Externí odkaz:
https://doaj.org/article/acc5fa0a3b784607867755de3cac6cfe
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Astrocytes are specialized non-neuronal glial cells of the central nervous system, contributing to neuronal excitability and synaptic transmission (gliotransmission). Astrocytes play a key roles in epileptogenesis and seizure generation. Epilepsy, as
Externí odkaz:
https://doaj.org/article/3f49c45af86e42d0ae4e143a1ebc7c77
Autor:
Nihan Çarçak, Melike Sahiner, Özlem Akman, Medine Gulcebi Idrizoglu, Miguel Angel Cortez, O. Carter Snead, Esat Eşkazan, Filiz Onat
Publikováno v:
İstanbul Kuzey Klinikleri, Vol 7, Iss 1, Pp 25-34 (2020)
OBJECTIVE: This study aimed to investigate the effects of γ-butyrolactone (GBL), a prodrug of gamma-Hydroxybutyric acid -induced absence seizures on the development of kindling in Wistar rats. METHODS: Three groups of adult male Wistar rats under an
Externí odkaz:
https://doaj.org/article/847e34ff8d694b588b60683233506799
Publikováno v:
İstanbul Medical Journal, Vol 20, Iss 6, Pp 563-567 (2019)
Introduction:Clopidogrel treatment is one of the standard treatments in terms of reducing mortality and morbidity in patients with cerebrovascular disease diagnosed with large artery atherosclerosis. However, resistance to clopidogrel treatment is a
Externí odkaz:
https://doaj.org/article/7834f042d3aa4e91a37dd1d0271a32a2
Autor:
Nihan ÇARÇAK, Melis YAVUZ, Tuğba ERYİĞİT, Akif Hakan KURT, Meral URHAN KÜÇÜK, Filiz ONAT, Kansu BÜYÜKAFŞAR
Publikováno v:
Archives of Epilepsy, Vol 25, Iss 1, Pp 1-7 (2019)
Objectives:Rho/Rho-kinase (ROCK) signaling has been shown to contribute to neuroinflammation, epileptogenesis, and seizures in convulsivetype epilepsy models. However, this pathway has not been investigated in the pathophysiology of absence epilepsy.
Externí odkaz:
https://doaj.org/article/542ae60d968f49da938e37c1da8bcf61
Publikováno v:
Neurobiology of Disease, Vol 32, Iss 3, Pp 355-363 (2008)
Genetic Absence Epilepsy Rats from Strasbourg (GAERS) are resistant to amygdaloid kindling. Since in GAERS the characteristics of spike-and-wave discharges (SWDs) change with age, we have studied the relation between SWD maturation and the developmen
Externí odkaz:
https://doaj.org/article/c1e5bf6f09e84d458f34ca40c1d19e91
Publikováno v:
Pharmacology. 107:227-234
Introduction: Hyperpolarization-activated cyclic nucleotide-gated (HCN) channel currents of Ih and absence epilepsy seizures are associated, but studies reveal differential results. Objective: In our study, we aimed to investigate the role of the HCN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::436d2dd40082726438981c0572667ced
https://doi.org/10.1159/000520059
https://doi.org/10.1159/000520059
Publikováno v:
Epilepsia. 61:2825-2835
Objective The role of α2A adrenergic receptors (α2A ARs) in absence epilepsy is not well characterized. Therefore, we investigated the outcomes of the specific antagonism of α2A ARs on the spike-and-wave discharges (SWDs) in genetic absence epilep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd16912cf1aa3bdaa9334de276a422b2
https://doi.org/10.1111/epi.16728
https://doi.org/10.1111/epi.16728
Automatic Detection Of Seizure Activity From EEG Recordings Of Genetic Rat Model Of Absence Epilepsy
Autor:
Filiz Onat, Melis Yavuz, Besir Ozmen, Zoltán Molnár, Rifat Koray Ciftci, Nihan Çarçak, Medine Gülçebi İdriz Oğlu
Publikováno v:
SIU
Spike-and-wave discharge is a phenomenon that occurs during absence epilepsy. The detection of these waveforms can provide an important tool for the different aspects of epilepsy. However, the manual detection of these seizures is not simple as it ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::578fdc328c37f2730afdbc1a0b82f3fa
https://doi.org/10.1109/siu53274.2021.9478005
https://doi.org/10.1109/siu53274.2021.9478005