Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Nihal Tümer"'
Autor:
Erin Bruce, Christy S. Carter, Drake Morgan, Hale Z. Toklu, Philip J. Scarpace, Colin Sumners, Yasemin Sakarya, Nihal Tümer, Nataliya Kirichenko
Publikováno v:
Experimental Gerontology. 111:133-140
The obesity epidemic is multi-generational and is particularly debilitating in the aging population, necessitating the use of pharmaceutical interventions. Recent evidence suggests that increasing the activity of the angiotensin converting enzyme-2 [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c7cab3e92eb4bc706d842016efd095c
https://doi.org/10.1016/j.exger.2018.07.008
https://doi.org/10.1016/j.exger.2018.07.008
Autor:
Michael Matheny, Kevin K.W. Wang, Zhihui Yang, Hale Z. Toklu, Judy M. Muller-Delp, Yasemin Sakarya, Philip J. Scarpace, Nihal Tümer, Kevin H. Strang, Nataliya Kirichenko, Sehkar Oktay
Publikováno v:
Behavioural Brain Research. 340:14-22
Overpressure blast-wave induced brain injury (OBI) and its long-term neurological outcome pose significant concerns for military personnel. Our aim is to investigate the mechanism of injury due to OBI.Rats were divided into 3 groups: (1) Control, (2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2318869fde7f3a05a78e634cc7073fb
https://doi.org/10.1016/j.bbr.2017.04.025
https://doi.org/10.1016/j.bbr.2017.04.025
Autor:
Isabelle M. Côté, Philip J. Scarpace, Sara M. Green, Nihal Tümer, Drake Morgan, Christy S. Carter
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 96:308-312
Recent evidence indicate that melanotan II (MTII) reduces body mass independently of caloric reduction. Because MTII induces a transient hypophagia, caloric reduction is still considered a primary mechanism for MTII-mediated body mass loss. To examin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce1a3bd3261ce6d615369f99953cd67
https://doi.org/10.1139/cjpp-2017-0440
https://doi.org/10.1139/cjpp-2017-0440
Autor:
Bilgen Basgut, Nataliya Kirichenko, Benedek Erdos, Mary Woods, Melissa A. Whidden, Philip J. Scarpace, Nihal Tümer
Publikováno v:
Pharmacology. 100:105-114
Aim: The aim of this study was to investigate the effect of a high salt (HS) diet on age-related changes in blood pressure (BP) and the possible role played by regulatory central mechanisms. Methods: Young (5 months) and old (27 months) male Fischer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f25069f899b14b0411ae6ebb19e140f1
https://doi.org/10.1159/000472259
https://doi.org/10.1159/000472259
Autor:
Nihal Tümer, Christy S. Carter, Philip J. Scarpace, Hale Z. Toklu, Yasemin Sakarya, Erin Bruce, Nataliya Kirichenko, Drake Morgan, Michael Matheny
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 43:802-807
The authors have previously demonstrated that a low and intermittent peripheral dose of rapamycin (1 mg/kg three times/week) to rats inhibited mTORC1 signalling, but avoided the hyperlipidemia and diabetes-like syndrome associated with higher doses o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a23af31e9308189cf2c2ce90aea0e74c
https://doi.org/10.1111/1440-1681.12601
https://doi.org/10.1111/1440-1681.12601
Publikováno v:
Journal of Exercise Nutrition & Biochemistry
[Purpose] Both aging and the consumption of a high salt diet are associated with clear changes in the vascular system that can lead to the development of cardiovascular disease; however the mechanisms are not clearly understood. Therefore, we examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ca7264cfd39e1e726c12037c98025c
https://doi.org/10.20463/jenb.2016.06.20.2.8
https://doi.org/10.20463/jenb.2016.06.20.2.8
Autor:
Philip J. Scarpace, J. Ignacio Aguirre, Nihal Tümer, Cong Chen, Dana M. Otzel, Hale Z. Toklu, Yasemin Sakarya, Thomas J. Wronski, Joshua F. Yarrow, Ean G. Phillips, Alex Balaez
Publikováno v:
Bone. 85:99-106
Dietary-induced obesity (DIO) resulting from high-fat (HF) or high-sugar diets produces a host of deleterious metabolic consequences including adverse bone development. We compared the effects of feeding standard rodent chow (Control), a 30% moderate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365798b6425a259a9cf614bf3be9b345
https://doi.org/10.1016/j.bone.2016.02.004
https://doi.org/10.1016/j.bone.2016.02.004
Autor:
Nihal Tümer, Tijen Utkan, Yasemin Sakarya, Benedek Erdos, Philip J. Scarpace, Nataliya Kirichenko, Semil Selcen Gocmez, Melissa A. Whidden
Publikováno v:
Journal of Exercise Nutrition & Biochemistry
Purpose To determine whether resveratrol improves the adverse effects age on vascular function in mesenteric arteries (MAs), and diminishes the hyperactivity in adrenal gland with age. Methods Male F344 x Brown Norway rats were assigned to 6-month co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2383aea713bbf8fa05e27b1a69c361ad
https://doi.org/10.20463/jenb.2016.03.20.1.2
https://doi.org/10.20463/jenb.2016.03.20.1.2
Autor:
Hale Z. Toklu, Christy S. Carter, Drake Morgan, Isabelle M. Côté, Philip J. Scarpace, Sara M. Green, Nihal Tümer
Reducing body weight has been shown to lower blood pressure in obesity-related hypertension. However, success of those lifestyle interventions is limited due to poor long-term compliance. Emerging evidence indicates that feeding schedule plays a role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2ddd493bf4b7d73e6da34c2d1a94e1
https://europepmc.org/articles/PMC6230890/
https://europepmc.org/articles/PMC6230890/
Autor:
Kurt J. Sollanek, Hale Z. Toklu, Michael P. Wiggs, Nihal Tümer, Oh Sung Kwon, Ashley J. Smuder, Aaron B. Morton, Stephanie E. Hall, Scott K. Powers, Erin E. Talbert
Publikováno v:
Journal of Applied Physiology. 119:1033-1041
Mechanical ventilation is a life-saving intervention for patients in respiratory failure. Unfortunately, prolonged ventilator support results in diaphragmatic atrophy and contractile dysfunction leading to diaphragm weakness, which is predicted to co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768ea83f246f416be136c99fba9ab88c
https://doi.org/10.1152/japplphysiol.00237.2015
https://doi.org/10.1152/japplphysiol.00237.2015