Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nihal Karakas"'
Autor:
Metehan Ilter, Ramazan Kasmer, Farzaneh Jalalypour, Canan Atilgan, Ozan Topcu, Nihal Karakas, Ozge Sensoy
Publikováno v:
eLife, Vol 11 (2022)
Undruggability of RAS proteins has necessitated alternative strategies for the development of effective inhibitors. In this respect, phosphorylation has recently come into prominence as this reversible post-translational modification attenuates sensi
Externí odkaz:
https://doaj.org/article/4e29c60ddede4a0291dd5d0029a210ac
Autor:
Bilgesu Onur Sucu, Elif Beyza Koc, Ozgecan Savlug Ipek, Afranur Mirat, Furkan Almas, Melike Aybala Guzel, Berna Dogan, Damla Uludag, Nihal Karakas, Serdar Durdagi, Mustafa Guzel
Glioblastoma Multiforme (GBM) is the most aggressive brain tumor and classified as one of the deadliest cancers. The current treatment plans for GBM remains to be ineffective because of its rapid progress and inability of the drugs used to cross the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f4e8f713887971e8f5a0a382e20fdc
https://hdl.handle.net/20.500.12511/9120
https://hdl.handle.net/20.500.12511/9120
Autor:
Nihal, Karakas, Mehmet Evren, Okur, Irem, Ozturk, Sule, Ayla, Ayse Esra, Karadag, Derya Çiçek, Polat
Publikováno v:
Medeniyet Medical Journal
Blackthorn (Prunus spinosa L. (Rosaceae) is a shrup whose fruits are consumed as food in Turkey. This study was aimed to evaluate antioxidant activity of methanol extract of P. spinosa and its cytotoxic effects on cancer cell lines.Methanol extract o
Autor:
Güven Çetin, Tuba Kunduraci, Mehmet Taha Yildiz, Merve Zaim, Nihal Karakas, Sevim Isik, Yesim Negis, Gulsum Arikan
Publikováno v:
Annals of Hematology. 94:307-318
Two isoforms of DNA topoisomerase II (topo II) have been identified in mammalian cells, named topo II alpha and topo II beta. Topo II alpha plays an essential role in segregation of daughter chromosomes and thus for cell proliferation in mammalian ce
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 47:484-491
The differentiation of human mesenchymal stem cells (hMSCs) into neural cells in vitro provides a potential tool to be utilized for cell therapy of neurodegenerative disorders. Although previous studies repeated different protocols for the induction
Publikováno v:
Cell Biology International Reports
hMSCs (human mesenchymal stem cells) express two isoforms of DNA topo II (topoisomerase II). Although both isoforms have the same catalytic activity, they are specialized for different functions in the cell: while topo IIα is essential for chromosom
Autor:
Damla Uludağ, Sadık Bay, Bilgesu Onur Sucu, Özgecan Şavluğ İpek, Thomas Mohr, Mustafa Güzel, Nihal Karakaş
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Change in the energy metabolism of cancer cells, which display significant differences compared to normal cells, is a rising phenomenon in developing new therapeutic approaches against cancers. One of the metabolic enzymes, hexokinase-II (HK-II) is i
Externí odkaz:
https://doaj.org/article/2f2e98f9bf9a49a594df53503809c75d
Autor:
Nihal Karakaş, Süleyman Üçüncüoğlu, Damla Uludağ, Birnur Sinem Karaoğlan, Khalid Shah, Gürkan Öztürk
Publikováno v:
Cells, Vol 11, Iss 3, p 465 (2022)
The novel pathogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). Mesenchymal stem cells (MSCs) are currently utilized in clinics for pulmonary inflammatory diseases, including acute respira
Externí odkaz:
https://doaj.org/article/174e434c26244d92a40a5ece1fd256a0
Autor:
Nihal Karakaş, Sadık Bay, Nezaket Türkel, Nurşah Öztunç, Merve Öncül, Hülya Bilgen, Khalid Shah, Fikrettin Şahin, Gürkan Öztürk
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0228510 (2020)
Mesenchymal stem cells have the ability to transdifferentiate into neurons and therefore one of the potential adult stem cell source for neuronal tissue regeneration applications and understanding neurodevelopmental processes. In many studies on huma
Externí odkaz:
https://doaj.org/article/76f9dbe77a6e4f07ae1c857b23c707ed