Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nihal Almuraikhi"'
Publikováno v:
Saudi Dental Journal, Vol 33, Iss 8, Pp 1119-1125 (2021)
Objective: The research was designed to assess silica calcium phosphate nanocomposite (SCPC) biocompatibility and bioactivity as an osteoinductive scaffold and cell carrier. Consequently, the ability of cell seeded SCPC implant to regenerate a critic
Externí odkaz:
https://doaj.org/article/ba7da78597ca448c9f59cb50663184fd
Publikováno v:
Saudi Dental Journal, Vol 33, Iss 5, Pp 248-255 (2021)
Background: The morbidities and complications reported in the reconstruction of large bony defects have inspired progression in the field of bioengineering, with a recent breakthrough for the use of decellularized skeletal muscle grafts (DSMG). Aim:
Externí odkaz:
https://doaj.org/article/8b45e499864b461fbd316d6d0a40564d
Autor:
Nihal AlMuraikhi
Publikováno v:
Journal of Nature and Science of Medicine, Vol 3, Iss 4, Pp 322-328 (2020)
Coronavirus disease 2019 (COVID-19) is a highly contagious respiratory infection that emerges as a serious healthcare problem and becomes a global pandemic. The disease is caused by a novel virus called SARS-CoV-2. The initial site of infection is th
Externí odkaz:
https://doaj.org/article/b290d678e6d94a768682949b9adc6c34
Autor:
Nihal AlMuraikhi, Dalia Ali, Aliah Alshanwani, Radhakrishnan Vishnubalaji, Muthurangan Manikandan, Muhammad Atteya, Abdulaziz Siyal, Musaad Alfayez, Abdullah Aldahmash, Moustapha Kassem, Nehad M. Alajez
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-10 (2018)
Abstract Background Better understanding of the signaling pathways that regulate human bone marrow stromal stem cell (hBMSC) differentiation into bone-forming osteoblasts is crucial for their clinical use in regenerative medicine. Chemical biology ap
Externí odkaz:
https://doaj.org/article/d4c4e1fe6cc84dd89d9ccc33c4630c23
Autor:
Nihal AlMuraikhi, Dalia Ali, Radhakrishnan Vishnubalaji, Muthurangan Manikandan, Muhammad Atteya, Abdulaziz Siyal, Musaad Alfayez, Abdullah Aldahmash, Moustapha Kassem, Nehad M. Alajez
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Background. Chemical biology approaches using small molecule inhibitors targeting specific signaling pathways are useful tools to dissect the molecular mechanisms governing stem cell differentiation and for their possible use in therapeutic intervent
Externí odkaz:
https://doaj.org/article/62dfd20a09014b97bcfeed25b81a45d6
Autor:
Nihal AlMuraikhi, Nuha Almasoud, Sarah Binhamdan, Ghaydaa Younis, Dalia Ali, Muthurangan Manikandan, Radhakrishnan Vishnubalaji, Muhammad Atteya, Abdulaziz Siyal, Musaad Alfayez, Abdullah Aldahmash, Moustapha Kassem, Nehad M. Alajez
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Background. Hedgehog (Hh) signaling is essential for osteoblast differentiation of mesenchymal progenitors during endochondral bone formation. However, the critical role of Hh signaling during adult bone remodeling remains to be elucidated. Methods.
Externí odkaz:
https://doaj.org/article/1f652ce2bc424c3288a264907e42aba6
Autor:
Nuha Almasoud, Sarah Binhamdan, Ghaydaa Younis, Hanouf Alaskar, Amal Alotaibi, Muthurangan Manikandan, Musaad Alfayez, Moustapha Kassem, Nihal AlMuraikhi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/edfafcb60b50430fbc8bc7f2791a627e
Autor:
Nihal AlMuraikhi, Hanouf Alaskar, Sarah Binhamdan, Amal Alotaibi, Moustapha Kassem, Musaad Alfayez
Publikováno v:
Molecules, Vol 26, Iss 3, p 606 (2021)
Several signalling pathways, including the JAK/STAT signalling pathway, have been identified to regulate the differentiation of human bone marrow skeletal (mesenchymal) stem cells (hBMSCs) into bone-forming osteoblasts. Members of the JAK family medi
Externí odkaz:
https://doaj.org/article/b73ba496ecf646eeba5c3bf97bc50e8b
Autor:
Nihal Almuraikhi
Publikováno v:
Cell Biochemistry and Function.
Autor:
Nihal AlMuraikhi, Sarah Binhamdan, Hanouf Alaskar, Amal Alotaibi, Sumaiya Tareen, Manikandan Muthurangan, Musaad Alfayez
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7164
Small-molecule-inhibitor-based bone differentiation has been recently exploited as a novel approach to regulating osteogenesis-related signaling pathways. In this study, we identified 1-Azakenpaullone, a highly selective inhibitor of glycogen synthas