Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Nigel Yarlett"'
Autor:
Nigel Yarlett, Mary Morada, Deborah A Schaefer, Kevin Ackman, Elizabeth Carranza, Rodrigo de Paula Baptista, Michael W Riggs, Jessica C Kissinger
Publikováno v:
PLoS Pathogens, Vol 20, Iss 2, p e1011992 (2024)
Recent advances in the in vitro cultivation of Cryptosporidium parvum using hollow fiber bioreactor technology (HFB) have permitted continuous growth of parasites that complete all life cycle stages. The method provides access to all stages of the pa
Externí odkaz:
https://doaj.org/article/0e2fb4f6db3040a782fc7aca4017fc3f
Autor:
Kamal El Bissati, Henry Redel, Li-Min Ting, Joseph D. Lykins, Martin J. McPhillie, Rajendra Upadhya, Patrick M. Woster, Nigel Yarlett, Kami Kim, Louis M. Weiss
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Twenty-two compounds belonging to several classes of polyamine analogs have been examined for their ability to inhibit the growth of the human malaria parasite Plasmodium falciparum in vitro and in vivo. Four lead compounds from the thiourea sub-seri
Externí odkaz:
https://doaj.org/article/ef4b5cffc7f242ea9db0685ae8654b83
Autor:
Nigel Yarlett, Mary Morada
Publikováno v:
Bio-Protocol, Vol 8, Iss 15 (2018)
Continuous in vitro growth of Cryptosporidium parvum has proved difficult and conventional in vitro culture techniques result in short-term (2-5 days) growth of the parasite resulting in thin-walled oocysts that fail to propagate using in vitro cultu
Externí odkaz:
https://doaj.org/article/b63354639b474e3dba7254d67a55bdbe
Autor:
Jean J. Vanden Eynde, Annie Mayence, Madhusoodanan Mottamal, Cyrus J. Bacchi, Nigel Yarlett, Marcel Kaiser, Reto Brun, Tien L. Huang
Publikováno v:
Pharmaceuticals, Vol 9, Iss 2, p 20 (2016)
A series of 15 alkanediamide-linked bisbenzamidines and related analogs was synthesized and tested in vitro against two Trypanosoma brucei (T.b.) subspecies: T.b. brucei and T.b. rhodesiense, Trypanosoma cruzi, Leishmania donovani and two Plasmodium
Externí odkaz:
https://doaj.org/article/5058fb26228c47a4bb981b2eea64d1b9
Autor:
Robert T Jacobs, Bakela Nare, Stephen A Wring, Matthew D Orr, Daitao Chen, Jessica M Sligar, Matthew X Jenks, Robert A Noe, Tana S Bowling, Luke T Mercer, Cindy Rewerts, Eric Gaukel, Jennifer Owens, Robin Parham, Ryan Randolph, Beth Beaudet, Cyrus J Bacchi, Nigel Yarlett, Jacob J Plattner, Yvonne Freund, Charles Ding, Tsutomu Akama, Y-K Zhang, Reto Brun, Marcel Kaiser, Ivan Scandale, Robert Don
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 6, p e1151 (2011)
BACKGROUND: Human African trypanosomiasis (HAT) is an important public health problem in sub-Saharan Africa, affecting hundreds of thousands of individuals. An urgent need exists for the discovery and development of new, safe, and effective drugs to
Externí odkaz:
https://doaj.org/article/63cd3700496b42e79618890a16e02bc3
Autor:
Luke Mercer, Tana Bowling, Joe Perales, Jennifer Freeman, Tien Nguyen, Cyrus Bacchi, Nigel Yarlett, Robert Don, Robert Jacobs, Bakela Nare
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 2, p e956 (2011)
BACKGROUND: There is an urgent need to develop new, safe and effective treatments for human African trypanosomiasis (HAT) because current drugs have extremely poor safety profiles and are difficult to administer. Here we report the discovery of 2,4-d
Externí odkaz:
https://doaj.org/article/f33cc944a6f444ecb0c843d60ed2fb7e
Autor:
Nigel Yarlett
Publikováno v:
eLS. :1-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::445a670b0926e965089d9ad0e0d794dd
https://doi.org/10.1002/9780470015902.a0029376
https://doi.org/10.1002/9780470015902.a0029376
Autor:
David, Lloyd, Alan, Chapman, Jayne E, Ellis, Kevin, Hillman, Timothy A, Paget, Nigel, Yarlett, Alan G, Williams
Publikováno v:
Advances in microbial physiology. 79
Publications abound on the physiology, biochemistry and molecular biology of "anaerobic" protozoal parasites as usually grown under "anaerobic" culture conditions. The media routinely used are poised at low redox potentials using techniques that remo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2ced8f91d898252754de69c65103ff8
https://pubmed.ncbi.nlm.nih.gov/34836611
https://pubmed.ncbi.nlm.nih.gov/34836611
Autor:
Rama Subba Rao Vidadala, Grant R. Whitman, Carlie S. Dorr, Molly C. McCloskey, Ryan Choi, Mansi Khatod, Samuel L.M. Arnold, Mary Morada, Wesley C. Van Voorhis, Nigel Yarlett, Dustin J. Maly, Lynn K. Barrett, Matthew A. Hulverson
Publikováno v:
The Journal of Infectious Diseases
Recent studies have illustrated the burden Cryptosporidium infection places on the lives of malnourished children and immunocompromised individuals. Treatment options remain limited, and efforts to develop a new therapeutic are currently underway. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80e44e251c7a29d8d9352914f81a9a9
https://doi.org/10.1093/infdis/jiz269
https://doi.org/10.1093/infdis/jiz269
Autor:
K. Hillman, Alan Chapman, Jayne E. Ellis, Alan G. Williams, David Lloyd, Nigel Yarlett, Timothy A. Paget
Publikováno v:
Advances in Microbial Physiology ISBN: 9780128246023
Publications abound on the physiology, biochemistry and molecular biology of "anaerobic" protozoal parasites as usually grown under "anaerobic" culture conditions. The media routinely used are poised at low redox potentials using techniques that remo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d925f4f68853705a65a6103bb00536b
https://doi.org/10.1016/bs.ampbs.2021.09.001
https://doi.org/10.1016/bs.ampbs.2021.09.001
