Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Nigel W Fraser"'
Autor:
Xin Li, Yafen Yu, Fengchao Lang, Guijun Chen, Erlin Wang, Lihong Li, Zhuoran Li, Liping Yang, Xia Cao, Nigel W. Fraser, Jumin Zhou
Publikováno v:
Virology Journal, Vol 18, Iss 1, Pp 1-11 (2021)
Abstract Background Herpes Simplex Virus type I (HSV-1) is a large double-stranded DNA virus that enters productive infection in epithelial cells and reorganizes the host nucleus. Cohesin, a major constituent of interphase and mitotic chromosomes com
Externí odkaz:
https://doaj.org/article/61d31ec103de41b59bf4fd2642120e23
Autor:
Erlin Wang, Yunshuang Ye, Ke Zhang, Jinlong Yang, Daohua Gong, Jianhua Zhang, Renjun Hong, Huan Zhang, Lihong Li, Guijun Chen, Liping Yang, Jianmei Liu, Hanyu Cao, Ting Du, Nigel W. Fraser, Le Cheng, Xia Cao, Jumin Zhou
Publikováno v:
Virology Journal, Vol 17, Iss 1, Pp 1-13 (2020)
Abstract Background Following acute infection, Herpes Simplex virus-1 (HSV-1) establishes lifelong latency and recurrent reactivation in the sensory neurons of trigeminal ganglia (TG). Infected tree shrew differs from mouse and show characteristics s
Externí odkaz:
https://doaj.org/article/613ffbe4d2774f41a5d56ca8f583f458
Autor:
Erlin Wang, Xinwei Huang, Yunshuang Ye, Shiqing Zou, Guijun Chen, Liping Yang, Nigel W. Fraser, Fukai Bao, Jumin Zhou, Xia Cao
Publikováno v:
Virologica Sinica. 38:108-118
Herpes simplex virus-1 (HSV-1) is a widespread neurotropic virus that can reach the brain and cause a rare but acute herpes simplex encephalitis (HSE) with a high mortality rate. Most patients present with changes in neurological and behavioral statu
Autor:
Erlin Wang, Yunshuang Ye, Ke Zhang, Jinlong Yang, Daohua Gong, Jianhua Zhang, Shijun Hong, Huan Zhang, Lihong Li, Guijun Chen, Liping Yang, Jianmei Liu, Hanyu Cao, Ting Du, Nigel W. Fraser, Le Cheng, Xia Cao, Jumin Zhou
Publikováno v:
Virology Journal, Vol 17, Iss 1, Pp 1-2 (2020)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/162f1a61447b4559baa8aec8db1871fb
Autor:
Fengchao Lang, Xin Li, Olga Vladimirova, Benxia Hu, Guijun Chen, Yu Xiao, Vikrant Singh, Danfeng Lu, Lihong Li, Hongbo Han, J. M. A. S. P. Wickramasinghe, Sheryl T. Smith, Chunfu Zheng, Qihan Li, Paul M. Lieberman, Nigel W. Fraser, Jumin Zhou
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/62e9749c58174ec9b9cb01936740bffa
Autor:
Zhong Deng, Eui Tae Kim, Olga Vladimirova, Jayaraju Dheekollu, Zhuo Wang, Alyshia Newhart, Dongmei Liu, Jaclyn L. Myers, Scott E. Hensley, Jennifer Moffat, Susan M. Janicki, Nigel W. Fraser, David M. Knipe, Matthew D. Weitzman, Paul M. Lieberman
Publikováno v:
Cell Reports, Vol 9, Iss 6, Pp 2263-2278 (2014)
Telomeres protect the ends of cellular chromosomes. We show here that infection with herpes simplex virus 1 (HSV-1) results in chromosomal structural aberrations at telomeres and the accumulation of telomere dysfunction-induced DNA damage foci (TIFs)
Externí odkaz:
https://doaj.org/article/56fc1baaf8bc402da5a02edc00a53327
Autor:
Fengchao Lang, Nigel W. Fraser, Erlin Wang, Yafen Yu, Liping Yang, Lihong Li, Zhuoran Li, Guijun Chen, Xia Cao, Jumin Zhou, Xin Li
Publikováno v:
Virology Journal, Vol 18, Iss 1, Pp 1-11 (2021)
Virology Journal
Virology Journal
Background Herpes Simplex Virus type I (HSV-1) is a large double-stranded DNA virus that enters productive infection in epithelial cells and reorganizes the host nucleus. Cohesin, a major constituent of interphase and mitotic chromosomes comprised of
Autor:
Shengtao Fan, Xingli Xu, Yun Liao, Yongrong Wang, Jianbin Wang, Min Feng, Lichun Wang, Ying Zhang, Zhanlong He, Fengmei Yang, Nigel W. Fraser, Qihan Li
Publikováno v:
Viruses, Vol 10, Iss 5, p 234 (2018)
Herpes simplex virus type 1(HSV-1) presents a conundrum to public health worldwide because of its specific pathogenicity and clinical features. Some experimental vaccines, such as the recombinant viral glycoproteins, exhibit the viral immunogenicity
Externí odkaz:
https://doaj.org/article/ded69b218fb44d019ee193ee7de90ca9
Autor:
Jaewook Oh, Iryna F Sanders, Eric Z Chen, Hongzhe Li, John W Tobias, R Benjamin Isett, Sindura Penubarthi, Hao Sun, Don A Baldwin, Nigel W Fraser
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117471 (2015)
HSV is a large double stranded DNA virus, capable of causing a variety of diseases from the common cold sore to devastating encephalitis. Although DNA within the HSV virion does not contain any histone protein, within 1 h of infecting a cell and ente
Externí odkaz:
https://doaj.org/article/8afcaf0f2bf14eada6985e726a4e8ef6
Autor:
Wenpei Liu, Gerald Griffin, Trena Clarke, Michael K Parente, Rita J Valentino, John H Wolfe, Nigel W Fraser
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
Genetic diseases of the brain usually have pathologic lesions distributed throughout, thus requiring global correction. Herpes simplex virus-1 (HSV-1) vectors may be especially useful for gene delivery in these disorders since they can spread trans-s
Externí odkaz:
https://doaj.org/article/6b25cb0a96534986944aec5ede82ecf5